Pantothenate Kinase-Associated Neurodegeneration

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Pantothenate Kinase-Associated Neurodegeneration

"Pantothenate Kinase-Associated Neurodegeneration" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A rare autosomal recessive degenerative disorder which usually presents in late childhood or adolescence. Clinical manifestations include progressive MUSCLE SPASTICITY; hyperreflexia; MUSCLE RIGIDITY; DYSTONIA; DYSARTHRIA; and intellectual deterioration which progresses to severe dementia over several years. (From Adams et al., Principles of Neurology, 6th ed, p972; Davis & Robertson, Textbook of Neuropathology, 2nd ed, pp972-929)

Descriptor ID	D006211
MeSH Number(s)	C10.228.140.079.800 C10.228.140.744.320 C10.228.662.575 C10.574.500.700 C16.320.400.650
Concept/Terms	Pantothenate Kinase-Associated Neurodegeneration Pantothenate Kinase-Associated Neurodegeneration Neurodegeneration, Pantothenate Kinase-Associated Pantothenate Kinase Associated Neurodegeneration Hallervorden-Spatz Syndrome Hallervorden Spatz Syndrome PKAN Neuroaxonal Dystrophy, Juvenile-Onset PKAN Neuroaxonal Dystrophy, Juvenile Onset Pigmentary Pallidal Atrophy Pallidal Atrophy, Pigmentary Pigmentary Pallidal Degeneration Degeneration, Pigmentary Pallidal Hallervorden-Spatz Disease Hallervorden Spatz Disease Neurodegeneration With Brain Iron Accumulation 1

Below are MeSH descriptors whose meaning is more general than "Pantothenate Kinase-Associated Neurodegeneration".

Diseases [C]
Nervous System Diseases [C10]
Central Nervous System Diseases [C10.228]
Brain Diseases [C10.228.140]
Basal Ganglia Diseases [C10.228.140.079]
Pantothenate Kinase-Associated Neurodegeneration [C10.228.140.079.800]
Neuroaxonal Dystrophies [C10.228.140.744]
Pantothenate Kinase-Associated Neurodegeneration [C10.228.140.744.320]
Movement Disorders [C10.228.662]
Pantothenate Kinase-Associated Neurodegeneration [C10.228.662.575]
Neurodegenerative Diseases [C10.574]
Heredodegenerative Disorders, Nervous System [C10.574.500]
Pantothenate Kinase-Associated Neurodegeneration [C10.574.500.700]
Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
Genetic Diseases, Inborn [C16.320]
Heredodegenerative Disorders, Nervous System [C16.320.400]
Pantothenate Kinase-Associated Neurodegeneration [C16.320.400.650]

Below are MeSH descriptors whose meaning is related to "Pantothenate Kinase-Associated Neurodegeneration".

Below are MeSH descriptors whose meaning is more specific than "Pantothenate Kinase-Associated Neurodegeneration".

publications

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