RNA, Double-Stranded
"RNA, Double-Stranded" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
RNA consisting of two strands as opposed to the more prevalent single-stranded RNA. Most of the double-stranded segments are formed from transcription of DNA by intramolecular base-pairing of inverted complementary sequences separated by a single-stranded loop. Some double-stranded segments of RNA are normal in all organisms.
Descriptor ID |
D012330
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MeSH Number(s) |
D13.444.735.490 G02.111.570.790.486.775 G05.360.580.775
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "RNA, Double-Stranded".
Below are MeSH descriptors whose meaning is more specific than "RNA, Double-Stranded".
This graph shows the total number of publications written about "RNA, Double-Stranded" by people in UAMS Profiles by year, and whether "RNA, Double-Stranded" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2022 | 0 | 1 | 1 | 2020 | 1 | 0 | 1 | 2019 | 2 | 0 | 2 | 2018 | 1 | 1 | 2 | 2017 | 1 | 1 | 2 | 2015 | 1 | 0 | 1 | 2012 | 0 | 1 | 1 | 2008 | 0 | 1 | 1 | 2007 | 1 | 0 | 1 | 2006 | 1 | 0 | 1 | 2002 | 2 | 0 | 2 |
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Below are the most recent publications written about "RNA, Double-Stranded" by people in Profiles over the past ten years.
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van Ee A, Kim D, Prizmic V, Rho H, Park Y, Evans B, Kim S, Lee S, Wang G, Yu J, Kane MA, Garza LA. CD14 Is Induced by Retinoic Acid and Is Required for Double Stranded Noncoding RNA-Induced Regeneration. J Invest Dermatol. 2022 08; 142(8):2291-2294.e7.
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Petitjean O, Girardi E, Ngondo RP, Lupashin V, Pfeffer S. Genome-Wide CRISPR-Cas9 Screen Reveals the Importance of the Heparan Sulfate Pathway and the Conserved Oligomeric Golgi Complex for Synthetic Double-Stranded RNA Uptake and Sindbis Virus Infection. mSphere. 2020 11 11; 5(6).
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Greene E, Flees J, Dhamad A, Alrubaye A, Hennigan S, Pleimann J, Smeltzer M, Murray S, Kugel J, Goodrich J, Robertson A, Wideman R, Rhoads D, Dridi S. Double-Stranded RNA Is a Novel Molecular Target in Osteomyelitis Pathogenesis: A Translational Avian Model for Human Bacterial Chondronecrosis with Osteomyelitis. Am J Pathol. 2019 10; 189(10):2077-2089.
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Kim D, Chen R, Sheu M, Kim N, Kim S, Islam N, Wier EM, Wang G, Li A, Park A, Son W, Evans B, Yu V, Prizmic VP, Oh E, Wang Z, Yu J, Huang W, Archer NK, Hu Z, Clemetson N, Nelson AM, Chien A, Okoye GA, Miller LS, Ghiaur G, Kang S, Jones JW, Kane MA, Garza LA. Noncoding dsRNA induces retinoic acid synthesis to stimulate hair follicle regeneration via TLR3. Nat Commun. 2019 06 26; 10(1):2811.
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Zhou R, Wang G, Kim D, Kim S, Islam N, Chen R, Wang Z, Li A, McCarthy EF, Li L, Hu Z, Garza LA. dsRNA Sensing Induces Loss of Cell Identity. J Invest Dermatol. 2019 01; 139(1):91-99.
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Stuart JD, Holm GH, Boehme KW. Differential Delivery of Genomic Double-Stranded RNA Causes Reovirus Strain-Specific Differences in Interferon Regulatory Factor 3 Activation. J Virol. 2018 05 01; 92(9).
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Zhu AS, Li A, Ratliff TS, Melsom M, Garza LA. After Skin Wounding, Noncoding dsRNA Coordinates Prostaglandins and Wnts to Promote Regeneration. J Invest Dermatol. 2017 07; 137(7):1562-1568.
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Stuart JD, Phillips MB, Boehme KW. Reverse Genetics for Mammalian Orthoreovirus. Methods Mol Biol. 2017; 1602:1-10.
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Nelson AM, Reddy SK, Ratliff TS, Hossain MZ, Katseff AS, Zhu AS, Chang E, Resnik SR, Page C, Kim D, Whittam AJ, Miller LS, Garza LA. dsRNA Released by Tissue Damage Activates TLR3 to Drive Skin Regeneration. Cell Stem Cell. 2015 Aug 06; 17(2):139-51.
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