DNA, Circular
"DNA, Circular" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Any of the covalently closed DNA molecules found in bacteria, many viruses, mitochondria, plastids, and plasmids. Small, polydisperse circular DNA's have also been observed in a number of eukaryotic organisms and are suggested to have homology with chromosomal DNA and the capacity to be inserted into, and excised from, chromosomal DNA. It is a fragment of DNA formed by a process of looping out and deletion, containing a constant region of the mu heavy chain and the 3'-part of the mu switch region. Circular DNA is a normal product of rearrangement among gene segments encoding the variable regions of immunoglobulin light and heavy chains, as well as the T-cell receptor. (Riger et al., Glossary of Genetics, 5th ed & Segen, Dictionary of Modern Medicine, 1992)
Descriptor ID |
D004270
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MeSH Number(s) |
D13.444.308.283 G02.111.570.790.486.212 G05.360.580.156
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Concept/Terms |
DNA, Circular- DNA, Circular
- Circular DNAs
- DNAs, Circular
- Circular DNA
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Below are MeSH descriptors whose meaning is more general than "DNA, Circular".
Below are MeSH descriptors whose meaning is more specific than "DNA, Circular".
This graph shows the total number of publications written about "DNA, Circular" by people in UAMS Profiles by year, and whether "DNA, Circular" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2022 | 1 | 0 | 1 | 2021 | 1 | 0 | 1 | 2017 | 1 | 0 | 1 | 2012 | 0 | 1 | 1 | 2006 | 0 | 1 | 1 | 1990 | 1 | 0 | 1 |
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Below are the most recent publications written about "DNA, Circular" by people in Profiles over the past ten years.
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Wanchai V, Jenjaroenpun P, Leangapichart T, Arrey G, Burnham CM, T?mmler MC, Delgado-Calle J, Regenberg B, Nookaew I. CReSIL: accurate identification of extrachromosomal circular DNA from long-read sequences. Brief Bioinform. 2022 11 19; 23(6).
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Henriksen RA, Jenjaroenpun P, Sj?str?m IB, Jensen KR, Prada-Luengo I, Wongsurawat T, Nookaew I, Regenberg B. Circular DNA in the human germline and its association with recombination. Mol Cell. 2022 01 06; 82(1):209-217.e7.
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Wagner-Johnston ND, Lensing S, Noy A, Ratner L, Henry D, Lee JY, Silver S, Faham M, Ambinder RF. High frequency of identical clonal immunoglobulin DNA in pre-treatment tumor and plasma from untreated patients with HIV-associated lymphoma: prospective multicenter trial of the AIDS malignancies consortium (AMC 064). Leuk Lymphoma. 2017 12; 58(12):2939-2942.
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