 RNA
"RNA" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A polynucleotide consisting essentially of chains with a repeating backbone of phosphate and ribose units to which nitrogenous bases are attached. RNA is unique among biological macromolecules in that it can encode genetic information, serve as an abundant structural component of cells, and also possesses catalytic activity. (Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
| Descriptor ID |
D012313
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| MeSH Number(s) |
D13.444.735
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| Concept/Terms |
RNA- RNA
- Gene Products, RNA
- RNA Gene Products
- RNA, Non-Polyadenylated
- RNA, Non Polyadenylated
- Non-Polyadenylated RNA
- Non Polyadenylated RNA
- Ribonucleic Acid
- Acid, Ribonucleic
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Below are MeSH descriptors whose meaning is more general than "RNA".
Below are MeSH descriptors whose meaning is more specific than "RNA".
- RNA
- RNA Isoforms
- RNA Precursors
- RNA, Algal
- RNA, Antisense
- RNA, Archaeal
- RNA, Bacterial
- RNA, Chloroplast
- RNA, Complementary
- RNA, Double-Stranded
- RNA, Fungal
- RNA, Helminth
- RNA, Messenger
- RNA, Neoplasm
- RNA, Nuclear
- RNA, Plant
- RNA, Protozoan
- RNA, Ribosomal
- RNA, Satellite
- RNA, Transfer
- RNA, Untranslated
- RNA, Viral
This graph shows the total number of publications written about "RNA" by people in UAMS Profiles by year, and whether "RNA" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2024 | 1 | 1 | 2 | | 2023 | 2 | 6 | 8 | | 2022 | 3 | 6 | 9 | | 2021 | 2 | 1 | 3 | | 2020 | 0 | 2 | 2 | | 2019 | 1 | 2 | 3 | | 2018 | 1 | 2 | 3 | | 2017 | 1 | 0 | 1 | | 2016 | 2 | 1 | 3 | | 2015 | 3 | 1 | 4 | | 2014 | 1 | 1 | 2 | | 2013 | 1 | 2 | 3 | | 2012 | 0 | 6 | 6 | | 2011 | 1 | 2 | 3 | | 2010 | 3 | 1 | 4 | | 2009 | 0 | 3 | 3 | | 2008 | 1 | 5 | 6 | | 2007 | 0 | 4 | 4 | | 2006 | 3 | 6 | 9 | | 2005 | 1 | 6 | 7 | | 2004 | 0 | 3 | 3 | | 2003 | 0 | 3 | 3 | | 2002 | 0 | 4 | 4 | | 2001 | 0 | 2 | 2 | | 2000 | 0 | 2 | 2 | | 1999 | 1 | 0 | 1 | | 1998 | 1 | 0 | 1 | | 1996 | 0 | 1 | 1 | | 1995 | 0 | 1 | 1 | | 1992 | 0 | 1 | 1 | | 1991 | 0 | 1 | 1 | | 1990 | 2 | 1 | 3 | | 1989 | 0 | 1 | 1 |
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Below are the most recent publications written about "RNA" by people in Profiles over the past ten years.
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Biedka S, Alkam D, Washam CL, Yablonska S, Storey A, Byrum SD, Minden JS. One-pot method for preparing DNA, RNA, and protein for multiomics analysis. Commun Biol. 2024 Mar 14; 7(1):324.
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Zhang W, Huckaby B, Talburt J, Weissman S, Yang MQ. cnnImpute: missing value recovery for single cell RNA sequencing data. Sci Rep. 2024 02 16; 14(1):3946.
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Sziraki A, Zhong Y, Neltner AM, Niedowicz DM, Rogers CB, Wilcock DM, Nehra G, Neltner JH, Smith RR, Hartz AM, Cao J, Nelson PT. A high-throughput single-cell RNA expression profiling method identifies human pericyte markers. Neuropathol Appl Neurobiol. 2023 Dec; 49(6):e12942.
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Zbieranski N, Insuasti-Beltran G. Analytical Validation of an Automated Semiconductor-Based Next-Generation Sequencing Assay for Detection of DNA and RNA Alterations in Myeloid Neoplasms. J Mol Diagn. 2024 01; 26(1):29-36.
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Abe Y, Kofman ER, Almeida M, Ouyang Z, Ponte F, Mueller JR, Cruz-Becerra G, Sakai M, Prohaska TA, Spann NJ, Resende-Coelho A, Seidman JS, Stender JD, Taylor H, Fan W, Link VM, Cobo I, Schlachetzki JCM, Hamakubo T, Jepsen K, Sakai J, Downes M, Evans RM, Yeo GW, Kadonaga JT, Manolagas SC, Rosenfeld MG, Glass CK. RANK ligand converts the NCoR/HDAC3 co-repressor to a PGC1?- and RNA-dependent co-activator of osteoclast gene expression. Mol Cell. 2023 10 05; 83(19):3421-3437.e11.
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Chen M, Li J, Zhang L, Wang L, Cheng C, Ji H, Altilia S, Ding X, Cai G, Altomare D, Shtutman M, Byrum SD, Mackintosh SG, Feoktistov A, Soshnikova N, Mogila VA, Tatarskiy V, Erokhin M, Chetverina D, Prawira A, Ni Y, Urban S, McInnes C, Broude EV, Roninson IB. CDK8 and CDK19: positive regulators of signal-induced transcription and negative regulators of Mediator complex proteins. Nucleic Acids Res. 2023 08 11; 51(14):7288-7313.
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Reddy PH, Kshirsagar S, Bose C, Pradeepkiran JA, Hindle A, Singh SP, Reddy AP, Baig J. Rlip Reduction Induces Oxidative Stress and Mitochondrial Dysfunction in Mutant Tau-Expressed Immortalized Hippocampal Neurons: Mechanistic Insights. Cells. 2023 06 16; 12(12).
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Reddy PH, Kshirsagar S, Bose C, Pradeepkiran JA, Hindle A, Singh SP, Reddy AP. Rlip overexpression reduces oxidative stress and mitochondrial dysfunction in Alzheimer's disease: Mechanistic insights. Biochim Biophys Acta Mol Basis Dis. 2023 10; 1869(7):166759.
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Nau A, Shen Y, Sanchorawala V, Prokaeva T, Morgan GJ. Complete variable domain sequences of monoclonal antibody light chains identified from untargeted RNA sequencing data. Front Immunol. 2023; 14:1167235.
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Holloway KN, Pinson MR, Douglas JC, Rafferty TM, Kane CJM, Miranda RC, Drew PD. Cerebellar Transcriptomic Analysis in a Chronic plus Binge Mouse Model of Alcohol Use Disorder Demonstrates Ethanol-Induced Neuroinflammation and Altered Glial Gene Expression. Cells. 2023 02 25; 12(5).
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Wang G, Zeng D, Sweren E, Miao Y, Chen R, Chen J, Wang J, Liao W, Hu Z, Kang S, Garza LA. N6-methyladenosine RNA Methylation Correlates with Immune Microenvironment and Immunotherapy Response of Melanoma. J Invest Dermatol. 2023 08; 143(8):1579-1590.e5.
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Voinsky I, Fridland OY, Aran A, Frye RE, Gurwitz D. Machine Learning-Based Blood RNA Signature for Diagnosis of Autism Spectrum Disorder. Int J Mol Sci. 2023 Jan 20; 24(3).
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Allen RM, Michell DL, Cavnar AB, Zhu W, Makhijani N, Contreras DM, Raby CA, Semler EM, DeJulius C, Castleberry M, Zhang Y, Ramirez-Solano M, Zhao S, Duvall C, Doran AC, Sheng Q, Linton MF, Vickers KC. LDL delivery of microbial small RNAs drives atherosclerosis through macrophage TLR8. Nat Cell Biol. 2022 12; 24(12):1701-1713.
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Yeager C, Carter G, Gohara DW, Yennawar NH, Enemark EJ, Arnold JJ, Cameron CE. Enteroviral 2C protein is an RNA-stimulated ATPase and uses a two-step mechanism for binding to RNA and ATP. Nucleic Acids Res. 2022 11 11; 50(20):11775-11798.
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He S, Bhatt R, Brown C, Brown EA, Buhr DL, Chantranuvatana K, Danaher P, Dunaway D, Garrison RG, Geiss G, Gregory MT, Hoang ML, Khafizov R, Killingbeck EE, Kim D, Kim TK, Kim Y, Klock A, Korukonda M, Kutchma A, Lewis ZR, Liang Y, Nelson JS, Ong GT, Perillo EP, Phan JC, Phan-Everson T, Piazza E, Rane T, Reitz Z, Rhodes M, Rosenbloom A, Ross D, Sato H, Wardhani AW, Williams-Wietzikoski CA, Wu L, Beechem JM. High-plex imaging of RNA and proteins at subcellular resolution in fixed tissue by spatial molecular imaging. Nat Biotechnol. 2022 12; 40(12):1794-1806.
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Huang BJ, Smith JL, Farrar JE, Wang YC, Umeda M, Ries RE, Leonti AR, Crowgey E, Furlan SN, Tarlock K, Armendariz M, Liu Y, Shaw TI, Wei L, Gerbing RB, Cooper TM, Gamis AS, Aplenc R, Kolb EA, Rubnitz J, Ma J, Klco JM, Ma X, Alonzo TA, Triche T, Meshinchi S. Integrated stem cell signature and cytomolecular risk determination in pediatric acute myeloid leukemia. Nat Commun. 2022 09 19; 13(1):5487.
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Wada NI, Breen EC, Post WS, Stosor V, Macatangay BJ, Margolick JB. Long-term Trajectories of C-Reactive Protein Among Men Living With and Without HIV Infection in the Multicenter AIDS Cohort Study. J Gerontol A Biol Sci Med Sci. 2022 07 05; 77(7):1382-1388.
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Nehme R, Pietil?inen O, Artomov M, Tegtmeyer M, Valakh V, Lehtonen L, Bell C, Singh T, Trehan A, Sherwood J, Manning D, Peirent E, Malik R, Guss EJ, Hawes D, Beccard A, Bara AM, Hazelbaker DZ, Zuccaro E, Genovese G, Loboda AA, Neumann A, Lilliehook C, Kuismin O, Hamalainen E, Kurki M, Hultman CM, K?hler AK, Paulo JA, Ganna A, Madison J, Cohen B, McPhie D, Adolfsson R, Perlis R, Dolmetsch R, Farhi S, McCarroll S, Hyman S, Neale B, Barrett LE, Harper W, Palotie A, Daly M, Eggan K. The 22q11.2 region regulates presynaptic gene-products linked to schizophrenia. Nat Commun. 2022 06 27; 13(1):3690.
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Treas J, Roy P, Singh KP. Chronic coexposure to arsenic and estrogen potentiates genotoxic estrogen metabolic pathway and hypermethylation of DNA glycosylase MBD4 in human prostate epithelial cells. Prostate. 2022 09; 82(13):1273-1283.
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Ozaslan D, Byrd AK, Belachew B, Raney KD. Alignment of helicases on single-stranded DNA increases activity. Methods Enzymol. 2022; 672:29-54.
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Yang K, Han J, Asada M, Gill JG, Park JY, Sathe MN, Gattineni J, Wright T, Wysocki CA, de la Morena MT, Garza LA, Yan N. Cytoplasmic RNA quality control failure engages mTORC1-mediated autoinflammatory disease. J Clin Invest. 2022 01 18; 132(2).
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Wongsurawat T, Jenjaroenpun P, Nookaew I. Direct Sequencing of RNA and RNA Modification Identification Using Nanopore. Methods Mol Biol. 2022; 2477:71-77.
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Ferrone CK, Wong H, Semenuk L, Werunga B, Snetsinger B, Zhang X, Zhang G, Lui J, Richard-Carpentier G, Crocker S, Good D, Hay AE, Quest G, Carson N, Feilotter HE, Rauh MJ. Validation, Implementation, and Clinical Impact of the Oncomine Myeloid Targeted-Amplicon DNA and RNA Ion Semiconductor Sequencing Assay. J Mol Diagn. 2021 10; 23(10):1292-1305.
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Gao J, Gao Z, Putnam AA, Byrd AK, Venus SL, Marecki JC, Edwards AD, Lowe HM, Jankowsky E, Raney KD. G-quadruplex DNA inhibits unwinding activity but promotes liquid-liquid phase separation by the DEAD-box helicase Ded1p. Chem Commun (Camb). 2021 Jul 27; 57(60):7445-7448.
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Kiaei L, Kiaei M. RNA as a source of biomarkers for amyotrophic lateral sclerosis. Metab Brain Dis. 2022 08; 37(6):1697-1702.
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Shmookler Reis RJ, Atluri R, Balasubramaniam M, Johnson J, Ganne A, Ayyadevara S. "Protein aggregates" contain RNA and DNA, entrapped by misfolded proteins but largely rescued by slowing translational elongation. Aging Cell. 2021 05; 20(5):e13326.
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Marecki JC, Byrd AK, Raney KD. Identifying RNA Helicase Inhibitors Using Duplex Unwinding Assays. Methods Mol Biol. 2021; 2209:53-72.
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Rosa F, Busato S, Avaroma FC, Mohan R, Carpinelli N, Bionaz M, Osorio JS. Short communication: Molecular markers for epithelial cells across gastrointestinal tissues and fecal RNA in preweaning dairy calves. J Dairy Sci. 2021 Jan; 104(1):1175-1182.
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Pisu D, Huang L, Rin Lee BN, Grenier JK, Russell DG. Dual RNA-Sequencing of Mycobacterium tuberculosis-Infected Cells from a Murine Infection Model. STAR Protoc. 2020 12 18; 1(3):100123.
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Wen Y, Vechetti IJ, Alimov AP, Hoffman JF, Vergara VB, Kalinich JF, McCarthy JJ, Peterson CA. Time-course analysis of the effect of embedded metal on skeletal muscle gene expression. Physiol Genomics. 2020 12 01; 52(12):575-587.
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Chakraborty A, Jenjaroenpun P, Li J, El Hilali S, McCulley A, Haarer B, Hoffman EA, Belak A, Thorland A, Hehnly H, Schildkraut CL, Chen CL, Kuznetsov VA, Feng W. Replication Stress Induces Global Chromosome Breakage in the Fragile X Genome. Cell Rep. 2020 09 22; 32(12):108179.
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Saad AG, Grada Z, Bishop B, Abulsayen H, Hassan M, Firpo-Betancourt A, Teruya-Feldstein J, Fraig M, El Jamal SM. nCounter NanoString Assay Shows Variable Concordance With Immunohistochemistry-based Algorithms in Classifying Cases of Diffuse Large B-Cell Lymphoma According to the Cell-of-Origin. Appl Immunohistochem Mol Morphol. 2019 10; 27(9):644-648.
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Feng H, Bao S, Rahman MA, Weyn-Vanhentenryck SM, Khan A, Wong J, Shah A, Flynn ED, Krainer AR, Zhang C. Modeling RNA-Binding Protein Specificity In?Vivo by Precisely Registering Protein-RNA Crosslink Sites. Mol Cell. 2019 06 20; 74(6):1189-1204.e6.
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Gericke A, Wolff I, Musayeva A, Zadeh JK, Manicam C, Pfeiffer N, Li H, Xia N. Retinal arteriole reactivity in mice lacking the endothelial nitric oxide synthase (eNOS) gene. Exp Eye Res. 2019 04; 181:150-156.
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Gust KA, Chaitankar V, Ghosh P, Wilbanks MS, Chen X, Barker ND, Pham D, Scanlan LD, Rawat A, Talent LG, Quinn MJ, Vulpe CD, Elasri MO, Johnson MS, Perkins EJ, McFarland CA. Multiple environmental stressors induce complex transcriptomic responses indicative of phenotypic outcomes in Western fence lizard. BMC Genomics. 2018 Dec 05; 19(1):877.
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Aguilar-Lozano A, Baier S, Grove R, Shu J, Giraud D, Leiferman A, Mercer KE, Cui J, Badger TM, Adamec J, Andres A, Zempleni J. Concentrations of Purine Metabolites Are Elevated in Fluids from Adults and Infants and in Livers from Mice Fed Diets Depleted of Bovine Milk Exosomes and their RNA Cargos. J Nutr. 2018 12 01; 148(12):1886-1894.
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Kuznetsov VA, Bondarenko V, Wongsurawat T, Yenamandra SP, Jenjaroenpun P. Toward predictive R-loop computational biology: genome-scale prediction of R-loops reveals their association with complex promoter structures, G-quadruplexes and transcriptionally active enhancers. Nucleic Acids Res. 2018 09 06; 46(15):7566-7585.
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Zhou R, Wang G, Kim D, Kim S, Islam N, Chen R, Wang Z, Li A, McCarthy EF, Li L, Hu Z, Garza LA. dsRNA Sensing Induces Loss of Cell Identity. J Invest Dermatol. 2019 01; 139(1):91-99.
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Hughes MW, Jiang TX, Plikus MV, Guerrero-Juarez CF, Lin CH, Schafer C, Maxson R, Widelitz RB, Chuong CM. Msx2 Supports Epidermal Competency?during Wound-Induced Hair?Follicle Neogenesis. J Invest Dermatol. 2018 09; 138(9):2041-2050.
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Alonso A, Lasseigne BN, Williams K, Nielsen J, Ramaker RC, Hardigan AA, Johnston B, Roberts BS, Cooper SJ, Marsal S, Myers RM. aRNApipe: a balanced, efficient and distributed pipeline for processing RNA-seq data in high-performance computing environments. Bioinformatics. 2017 Jun 01; 33(11):1727-1729.
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Jenjaroenpun P, Wongsurawat T, Sutheeworapong S, Kuznetsov VA. R-loopDB: a database for R-loop forming sequences (RLFS) and R-loops. Nucleic Acids Res. 2017 01 04; 45(D1):D119-D127.
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Liu Y, Bailey JC, Helwa I, Dismuke WM, Cai J, Drewry M, Brilliant MH, Budenz DL, Christen WG, Chasman DI, Fingert JH, Gaasterland D, Gaasterland T, Gordon MO, Igo RP, Kang JH, Kass MA, Kraft P, Lee RK, Lichter P, Moroi SE, Realini A, Richards JE, Ritch R, Schuman JS, Scott WK, Singh K, Sit AJ, Song YE, Vollrath D, Weinreb R, Medeiros F, Wollstein G, Zack DJ, Zhang K, Pericak-Vance MA, Gonzalez P, Stamer WD, Kuchtey J, Kuchtey RW, Allingham RR, Hauser MA, Pasquale LR, Haines JL, Wiggs JL. A Common Variant in MIR182 Is Associated With Primary Open-Angle Glaucoma in the NEIGHBORHOOD Consortium. Invest Ophthalmol Vis Sci. 2016 08 01; 57(10):4528-4535.
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Stupnikov A, Tripathi S, de Matos Simoes R, McArt D, Salto-Tellez M, Glazko G, Dehmer M, Emmert-Streib F. samExploreR: exploring reproducibility and robustness of RNA-seq results based on SAM files. Bioinformatics. 2016 11 01; 32(21):3345-3347.
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Leach JC, Wang A, Ye K, Jin S. A RNA-DNA Hybrid Aptamer for Nanoparticle-Based Prostate Tumor Targeted Drug Delivery. Int J Mol Sci. 2016 Mar 14; 17(3):380.
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Rahmatallah Y, Emmert-Streib F, Glazko G. Gene set analysis approaches for RNA-seq data: performance evaluation and application guideline. Brief Bioinform. 2016 05; 17(3):393-407.
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Stupnikov A, Glazko GV, Emmert-Streib F. Effects of subsampling on characteristics of RNA-seq data from triple-negative breast cancer patients. Chin J Cancer. 2015 Aug 08; 34(10):427-38.
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Jenjaroenpun P, Wongsurawat T, Yenamandra SP, Kuznetsov VA. QmRLFS-finder: a model, web server and stand-alone tool for prediction and analysis of R-loop forming sequences. Nucleic Acids Res. 2015 Jul 01; 43(W1):W527-34.
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Walworth N, Pfreundt U, Nelson WC, Mincer T, Heidelberg JF, Fu F, Waterbury JB, Glavina del Rio T, Goodwin L, Kyrpides NC, Land ML, Woyke T, Hutchins DA, Hess WR, Webb EA. Trichodesmium genome maintains abundant, widespread noncoding DNA in situ, despite oligotrophic lifestyle. Proc Natl Acad Sci U S A. 2015 Apr 07; 112(14):4251-6.
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Epling LB, Grace CR, Lowe BR, Partridge JF, Enemark EJ. Cancer-associated mutants of RNA helicase DDX3X are defective in RNA-stimulated ATP hydrolysis. J Mol Biol. 2015 May 08; 427(9):1779-1796.
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Sinha S, Shukla S, Khan S, Farhan M, Kamal MA, Meeran SM. Telomeric Repeat Containing RNA (TERRA): Aging and Cancer. CNS Neurol Disord Drug Targets. 2015; 14(7):936-46.
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Rahmatallah Y, Emmert-Streib F, Glazko G. Comparative evaluation of gene set analysis approaches for RNA-Seq data. BMC Bioinformatics. 2014 Dec 05; 15:397.
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