 RecQ Helicases
"RecQ Helicases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of structurally-related DNA helicases that play an essential role in the maintenance of genome integrity. RecQ helicases were originally discovered in E COLI and are highly conserved across both prokaryotic and eukaryotic organisms. Genetic mutations that result in loss of RecQ helicase activity gives rise to disorders that are associated with CANCER predisposition and premature aging.
| Descriptor ID |
D053484
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| MeSH Number(s) |
D08.811.277.040.025.159.249 D08.811.277.040.025.800 D08.811.399.340.249
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| Concept/Terms |
RecQ Helicases- RecQ Helicases
- Helicases, RecQ
- RecQ Family of DNA Helicases
- RecQ Protein
RecQ4 Helicase- RecQ4 Helicase
- ATP-Dependent DNA Helicase Q4
- ATP Dependent DNA Helicase Q4
- RTS Helicase
- Helicase, RTS
- DNA Helicase RecQL4
- RecQL4 Helicase
- Helicase, RecQL4
RecQ2 Helicase- RecQ2 Helicase
- Helicase, RecQ2
- RecQL3 Helicase
- Helicase, RecQL3
- DNA Helicase, RecQ-like type 2
- DNA Helicase, RecQ like type 2
RecQL Helicase- RecQL Helicase
- Helicase, RecQL
- DNA Helicase RecQL
- ATP-Dependent DNA Helicase Q1
- ATP Dependent DNA Helicase Q1
- DNA Helicase Q1
- DNA-Dependent ATPase Q1
- DNA Dependent ATPase Q1
- RECQL1 Helicase
- Helicase, RECQL1
RecQ3 Helicase- RecQ3 Helicase
- Helicase, RecQ3
- RecQL2 Helicase
- Helicase, RecQL2
RecQ5 Helicase- RecQ5 Helicase
- Helicase, RecQ5
- RecQ5L Helicase
- Helicase, RecQ5L
- ATP-Dependent DNA Helicase Q5
- ATP Dependent DNA Helicase Q5
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Below are MeSH descriptors whose meaning is more general than "RecQ Helicases".
Below are MeSH descriptors whose meaning is more specific than "RecQ Helicases".
This graph shows the total number of publications written about "RecQ Helicases" by people in UAMS Profiles by year, and whether "RecQ Helicases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 1 | 0 | 1 | | 2020 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2012 | 1 | 1 | 2 | | 2009 | 0 | 1 | 1 | | 2008 | 1 | 0 | 1 | | 2007 | 0 | 1 | 1 | | 2002 | 0 | 1 | 1 |
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Below are the most recent publications written about "RecQ Helicases" by people in Profiles over the past ten years.
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Salunkhe S, Daley JM, Kaur H, Tomimatsu N, Xue C, Raina VB, Jasper AM, Rogers CM, Li W, Zhou S, Mojidra R, Kwon Y, Fang Q, Ji JH, Badamchi Shabestari A, Fitzgerald O, Dinh H, Mukherjee B, Habib AA, Hromas R, Mazin AV, Wasmuth EV, Olsen SK, Libich DS, Zhou D, Zhao W, Greene EC, Burma S, Sung P. Promotion of DNA end resection by BRCA1-BARD1 in homologous recombination. Nature. 2024 Oct; 634(8033):482-491.
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Daley JM, Tomimatsu N, Hooks G, Wang W, Miller AS, Xue X, Nguyen KA, Kaur H, Williamson E, Mukherjee B, Hromas R, Burma S, Sung P. Specificity of end resection pathways for double-strand break regions containing ribonucleotides and base lesions. Nat Commun. 2020 06 18; 11(1):3088.
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Wang W, Daley JM, Kwon Y, Xue X, Krasner DS, Miller AS, Nguyen KA, Williamson EA, Shim EY, Lee SE, Hromas R, Sung P. A DNA nick at Ku-blocked double-strand break ends serves as an entry site for exonuclease 1 (Exo1) or Sgs1-Dna2 in long-range DNA end resection. J Biol Chem. 2018 11 02; 293(44):17061-17069.
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Byrd AK, Raney KD. Fine tuning of a DNA fork by the RecQ helicase. Proc Natl Acad Sci U S A. 2015 Dec 15; 112(50):15263-4.
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