DNA Glycosylases
"DNA Glycosylases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of DNA repair enzymes that recognize damaged nucleotide bases and remove them by hydrolyzing the N-glycosidic bond that attaches them to the sugar backbone of the DNA molecule. The process called BASE EXCISION REPAIR can be completed by a DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE which excises the remaining RIBOSE sugar from the DNA.
Descriptor ID |
D045647
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MeSH Number(s) |
D08.811.074.249 D08.811.277.450.430.099
|
Concept/Terms |
DNA Glycosylases- DNA Glycosylases
- Glycosylases, DNA
- DNA Glycosylase
- Glycosylase, DNA
- DNA N-glycosidase
- DNA N glycosidase
|
Below are MeSH descriptors whose meaning is more general than "DNA Glycosylases".
Below are MeSH descriptors whose meaning is more specific than "DNA Glycosylases".
This graph shows the total number of publications written about "DNA Glycosylases" by people in UAMS Profiles by year, and whether "DNA Glycosylases" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2020 | 0 | 1 | 1 |
2014 | 0 | 1 | 1 |
2013 | 0 | 1 | 1 |
2011 | 1 | 0 | 1 |
2009 | 1 | 0 | 1 |
2008 | 2 | 0 | 2 |
2007 | 1 | 1 | 2 |
2003 | 1 | 0 | 1 |
1999 | 1 | 0 | 1 |
1997 | 1 | 0 | 1 |
1995 | 1 | 0 | 1 |
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Below are the most recent publications written about "DNA Glycosylases" by people in Profiles over the past ten years.
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Treas J, Roy P, Singh KP. Chronic coexposure to arsenic and estrogen potentiates genotoxic estrogen metabolic pathway and hypermethylation of DNA glycosylase MBD4 in human prostate epithelial cells. Prostate. 2022 09; 82(13):1273-1283.
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Daley JM, Tomimatsu N, Hooks G, Wang W, Miller AS, Xue X, Nguyen KA, Kaur H, Williamson E, Mukherjee B, Hromas R, Burma S, Sung P. Specificity of end resection pathways for double-strand break regions containing ribonucleotides and base lesions. Nat Commun. 2020 06 18; 11(1):3088.