DNA Ligases
"DNA Ligases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Poly(deoxyribonucleotide):poly(deoxyribonucleotide)ligases. Enzymes that catalyze the joining of preformed deoxyribonucleotides in phosphodiester linkage during genetic processes during repair of a single-stranded break in duplex DNA. The class includes both EC 6.5.1.1 (ATP) and EC 6.5.1.2 (NAD).
| Descriptor ID |
D011088
|
| MeSH Number(s) |
D08.811.074.500 D08.811.464.754.600
|
| Concept/Terms |
DNA Ligases- DNA Ligases
- Ligases, DNA
- Polydeoxyribonucleotide Ligases
- Ligases, Polydeoxyribonucleotide
- Polydeoxyribonucleotide Synthetases
- Synthetases, Polydeoxyribonucleotide
- DNA Joinases
- Joinases, DNA
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Below are MeSH descriptors whose meaning is more general than "DNA Ligases".
Below are MeSH descriptors whose meaning is more specific than "DNA Ligases".
This graph shows the total number of publications written about "DNA Ligases" by people in UAMS Profiles by year, and whether "DNA Ligases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
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Below are the most recent publications written about "DNA Ligases" by people in Profiles over the past ten years.
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Bhandari SK, Wiest N, Sallmyr A, Du R, Tomkinson AE. Redundant but essential functions of PARP1 and PARP2 in DNA ligase I-independent DNA replication. Nucleic Acids Res. 2024 Sep 23; 52(17):10341-10354.
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Bhandari SK, Wiest N, Sallmyr A, Du R, Ferry L, Defossez PA, Tomkinson AE. Unchanged PCNA and DNMT1 dynamics during replication in DNA ligase I-deficient cells but abnormal chromatin levels of non-replicative histone H1. Sci Rep. 2023 03 16; 13(1):4363.