 Protein Carbonylation
"Protein Carbonylation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The appearance of carbonyl groups (such as aldehyde or ketone groups) in PROTEINS as the result of several oxidative modification reactions. It is a standard marker for OXIDATIVE STRESS. Carbonylated proteins tend to be more hydrophobic and resistant to proteolysis.
| Descriptor ID |
D050050
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| MeSH Number(s) |
G02.111.087.682 G02.149.115.682 G03.495.710.690
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| Concept/Terms |
Protein Carbonylation- Protein Carbonylation
- Carbonylations, Protein
- Protein Carbonylations
- Carbonylation, Protein
- Protein Carbonyl Formation
- Carbonyl Formation, Protein
- Formation, Protein Carbonyl
- Carbonylated Protein Formation
- Formation, Carbonylated Protein
- Protein Formation, Carbonylated
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Below are MeSH descriptors whose meaning is more general than "Protein Carbonylation".
Below are MeSH descriptors whose meaning is more specific than "Protein Carbonylation".
This graph shows the total number of publications written about "Protein Carbonylation" by people in UAMS Profiles by year, and whether "Protein Carbonylation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 1 | 0 | 1 | | 2016 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 |
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Below are the most recent publications written about "Protein Carbonylation" by people in Profiles over the past ten years.
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Shearn CT, Pulliam CF, Pedersen K, Meredith K, Mercer KE, Saba LM, Orlicky DJ, Ronis MJ, Petersen DR. Knockout of the Gsta4 Gene in Male Mice Leads to an Altered Pattern of Hepatic Protein Carbonylation and Enhanced Inflammation Following Chronic Consumption of an Ethanol Diet. Alcohol Clin Exp Res. 2018 07; 42(7):1192-1205.
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Shearn CT, Orlicky DJ, McCullough RL, Jiang H, Maclean KN, Mercer KE, Stiles BL, Saba LM, Ronis MJ, Petersen DR. Liver-Specific Deletion of Phosphatase and Tensin Homolog Deleted on Chromosome 10 Significantly Ameliorates Chronic EtOH-Induced Increases in Hepatocellular Damage. PLoS One. 2016; 11(4):e0154152.
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Shearn CT, Fritz KS, Shearn AH, Saba LM, Mercer KE, Engi B, Galligan JJ, Zimniak P, Orlicky DJ, Ronis MJ, Petersen DR. Deletion of GSTA4-4 results in increased mitochondrial post-translational modification of proteins by reactive aldehydes following chronic ethanol consumption in mice. Redox Biol. 2016 Apr; 7:68-77.
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