 Interleukin-1 Receptor-Associated Kinases
"Interleukin-1 Receptor-Associated Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of intracellular signaling kinases that were identified by their ability to signal from the activated INTERLEUKIN-1 RECEPTORS. Signaling from these kinases involves their interaction with SIGNAL TRANSDUCING ADAPTOR PROTEINS such as MYELOID DIFFERENTIATION FACTOR 88 and TNF RECEPTOR-ASSOCIATED FACTOR 6.
| Descriptor ID |
D053592
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| MeSH Number(s) |
D08.811.913.696.620.682.700.526 D12.644.360.379 D12.776.476.384
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| Concept/Terms |
Interleukin-1 Receptor-Associated Kinases- Interleukin-1 Receptor-Associated Kinases
- Interleukin 1 Receptor Associated Kinases
- Kinases, Interleukin-1 Receptor-Associated
- Receptor-Associated Kinases, Interleukin-1
- IRAK Kinases
- Kinases, IRAK
- IL-1 Receptor-Associated Kinase
- IL 1 Receptor Associated Kinase
- Kinase, IL-1 Receptor-Associated
- Receptor-Associated Kinase, IL-1
- Interleukin-1 Receptor-Associated Kinase
- Interleukin 1 Receptor Associated Kinase
- Kinase, Interleukin-1 Receptor-Associated
- Receptor-Associated Kinase, Interleukin-1
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Below are MeSH descriptors whose meaning is more general than "Interleukin-1 Receptor-Associated Kinases".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-1 Receptor-Associated Kinases".
This graph shows the total number of publications written about "Interleukin-1 Receptor-Associated Kinases" by people in UAMS Profiles by year, and whether "Interleukin-1 Receptor-Associated Kinases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 | | 2015 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2011 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 |
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Below are the most recent publications written about "Interleukin-1 Receptor-Associated Kinases" by people in Profiles over the past ten years.
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Yang FM, Zuo Y, Zhou W, Xia C, Hahm B, Sullivan M, Cheng J, Chang HM, Yeh ET. sNASP inhibits TLR signaling to regulate immune response in sepsis. J Clin Invest. 2018 06 01; 128(6):2459-2472.
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Bagchi AK, Akolkar G, Mandal S, Ayyappan P, Yang X, Singal PK. Toll-like receptor 2 dominance over Toll-like receptor 4 in stressful conditions for its detrimental role in the heart. Am J Physiol Heart Circ Physiol. 2017 Jun 01; 312(6):H1238-H1247.
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Ryu S, Johnson A, Park Y, Kim B, Norris D, Armstrong CA, Song PI. The Alpha-Melanocyte-Stimulating Hormone Suppresses TLR2-Mediated Functional Responses through IRAK-M in Normal Human Keratinocytes. PLoS One. 2015; 10(8):e0136887.
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Lin KM, Hu W, Troutman TD, Jennings M, Brewer T, Li X, Nanda S, Cohen P, Thomas JA, Pasare C. IRAK-1 bypasses priming and directly links TLRs to rapid NLRP3 inflammasome activation. Proc Natl Acad Sci U S A. 2014 Jan 14; 111(2):775-80.
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Dilley MA, Jones SM, Perry TT, Scurlock AM, Brodie-Fowler M, Bufford JD, Pesek RD. Pneumococcal meningitis in a patient with IL-1 receptor-associated kinase-4 deficiency: a case of failed prophylaxis. J Allergy Clin Immunol Pract. 2013 Nov-Dec; 1(6):700-3.
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