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Edward Yeh

TitleDepartment Chairperson
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentDepartment Chairs, College of Medicine
Address324 UAMS Campus Dr.
Mail Slot # 832
Little Rock AR 72205
ORCID ORCID Icon0000-0001-8184-7294 Additional info
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    Collapse Affiliation 
    Collapse member of
    American Society of Clinical Investigation
    American Association of Physicians
    American Association for the Advancement of Science
    American Clinical and Climatology Association

    Collapse Biography 
    Collapse Leadership and Administrative Roles
    Chairman, Department of Internal Medicine

    Collapse education and training
    UC Berkeley, Berkeley CAA.B.05/1976Biochemistry
    UC Davis, Davis CAMD06/1980Medicine
    Collapse awards and honors
    2021 - 2024Scholar, Arkansas Research Alliances

    Collapse Research 
    Collapse research activities and funding
    7R01HL151993     (CHANG, HUI-MING)Jun 1, 2021 - May 31, 2025
    NIH/Nat. Heart, Lung & Blood Institute
    Prevention of Heart Failure induced by Doxorubicin with Early Administration of Dexrazoxane
    Role: Co-Investigator
    7R01HL126916     (YEH, EDWARD)Feb 1, 2021 - Aug 31, 2021
    NIH/Nat. Heart, Lung & Blood Institute
    Doxorubicin-induced Cardiotoxicity: The Role of Topoisomerase 2b
    Role: Principal Investigator
    7R01HL126916-06     (YEH, EDWARD)Feb 1, 2021 - Aug 31, 2021
    NIH/Nat. Heart, Lung & Blood Institute
    Doxorubicin-induced Cardiotoxicity: The Role of Topoisomerase 2b
    Role: Principal Investigator
    R01HL126916     (YEH, EDWARD T.H.)Apr 1, 2015 - Aug 31, 2021
    NIH
    Doxorubicin-induced Cardiotoxicity: the Role of Topoisomerase 2b
    Role: Principal Investigator
    R01CA139520     (YEH, EDWARD T.H.)Mar 1, 2009 - Dec 31, 2014
    NIH
    De-SUMOylation and the Hypoxic Response
    Role: Principal Investigator
    R01CA080089     (YEH, EDWARD T.H.)Feb 1, 2000 - Jan 31, 2006
    NIH
    PATHOBIOCHEMISTRY OF ACUTE PROMYELOCYTIC LEUKEMIA
    Role: Principal Investigator
    R21GM057502     (YEH, EDWARD T.H.)Sep 1, 1999 - Aug 31, 2001
    NIH
    STUDIES OF THE SENTRIN FAMILY OF UBIQUITIN-LIKE PROTEINS
    Role: Principal Investigator
    R01HL045851     (YEH, EDWARD T.H.)Feb 1, 1991 - Jul 31, 1999
    NIH
    PATHOBIOLOGY OF PAROXYSMAL NOCTURNAL HEMOGLOBINURIA
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse additional bibliographic sources
    The links below are provided by the researcher to provide access to external online bibliographies that they keep independently from the Profiles System.
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Chang HM, Hsu JY, Ahn C, Yeh ETH. Prevention of Heart Failure Induced by Doxorubicin with Early Administration of Dexrazoxane (PHOENIX Study): dose response and time course of dexrazoxane-induced degradation of topoisomerase 2b. Cardiooncology. 2025 May 02; 11(1):42. PMID: 40317097.
      View in: PubMed
    2. Wu YC, Su BH, Cheng WH, Zou CT, Yeh ETH, Yang FM. CYLD links the TRAF6/sNASP axis to TLR4 signaling in sepsis-induced acute lung injury. Cell Mol Life Sci. 2025 Mar 20; 82(1):124. PMID: 40108019.
      View in: PubMed
    3. Gautam N, Mounsey JP, Yeh ETH, Al'Aref SJ. Promises and challenges of machine learning for device therapy in heart failure. Eur Heart J. 2023 05 07; 44(18):1583-1585. PMID: 36806933.
      View in: PubMed
    4. Cheng J, Yeh ETH. Lactate: an intracellular metabolite regulates cell cycle progression. Life Metab. 2023 Aug; 2(4):load017. PMID: 39872246.
      View in: PubMed
    5. Wang C, Nistala R, Cao M, Pan Y, Behrens M, Doll D, Hammer RD, Nistala P, Chang HM, Yeh ETH, Kang X. Dipeptidylpeptidase 4 promotes survival and stemness of acute myeloid leukemia stem cells. Cell Rep. 2023 02 28; 42(2):112105. PMID: 36807138.
      View in: PubMed
    6. Dufour D, Dumontet T, Sahut-Barnola I, Carusi A, Onzon M, Pussard E, Wilmouth JJ, Olabe J, Lucas C, Levasseur A, Damon-Soubeyrand C, Pointud JC, Roucher-Boulez F, Tauveron I, Bossis G, Yeh ET, Breault DT, Val P, Lefran?ois-Martinez AM, Martinez A. Loss of SUMO-specific protease 2 causes isolated glucocorticoid deficiency by blocking adrenal cortex zonal transdifferentiation in mice. Nat Commun. 2022 12 21; 13(1):7858. PMID: 36543805.
      View in: PubMed
    7. Li J, Chang HM, Banchs J, Araujo DM, Hassan SA, Wagar EA, Yeh ETH, Meng QH. Detection of subclinical cardiotoxicity in sarcoma patients receiving continuous doxorubicin infusion or pre-treatment with dexrazoxane before bolus doxorubicin. Cardiooncology. 2020; 6:1. PMID: 32154027.
      View in: PubMed
    8. Yeh ETH, Ewer MS, Moslehi J, Dlugosz-Danecka M, Banchs J, Chang HM, Minotti G. Mechanisms and clinical course of cardiovascular toxicity of cancer treatment I. Oncology. Semin Oncol. 2019 12; 46(6):397-402. PMID: 31753424.
      View in: PubMed
    9. Jiang L, Han X, Wang J, Wang C, Sun X, Xie J, Wu G, Phan H, Liu Z, Yeh ETH, Zhang C, Zhao M, Kang X. Correction: SHP-1 regulates hematopoietic stem cell quiescence by coordinating TGF-? signaling. J Exp Med. 2018 08 06; 215(8):2227. PMID: 30006358.
      View in: PubMed
    10. Yang FM, Zuo Y, Zhou W, Xia C, Hahm B, Sullivan M, Cheng J, Chang HM, Yeh ET. sNASP inhibits TLR signaling to regulate immune response in sepsis. J Clin Invest. 2018 06 01; 128(6):2459-2472. PMID: 29733298.
      View in: PubMed
    11. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 29669741.
      View in: PubMed
    12. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 26065991.
      View in: PubMed
    13. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 25689261.
      View in: PubMed
    14. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 29321472.
      View in: PubMed
    15. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 29145955.
      View in: PubMed
    16. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 24344126.
      View in: PubMed
    17. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 19008217.
      View in: PubMed
    18. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 33512443.
      View in: PubMed
    19. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 32666886.
      View in: PubMed
    20. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 1829456.
      View in: PubMed
    21. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 1447204.
      View in: PubMed
    22. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 20181954.
      View in: PubMed
    23. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 10673031.
      View in: PubMed
    24. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 20841360.
      View in: PubMed
    25. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 22135400.
      View in: PubMed
    26. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 18708358.
      View in: PubMed
    27. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 18319102.
      View in: PubMed
    28. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 16961584.
      View in: PubMed
    29. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 16925949.
      View in: PubMed
    30. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 16409162.
      View in: PubMed
    31. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 16195483.
      View in: PubMed
    32. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 1594603.
      View in: PubMed
    33. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 11071919.
      View in: PubMed
    34. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 9029107.
      View in: PubMed
    35. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 9396466.
      View in: PubMed
    36. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 35386914.
      View in: PubMed
    37. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 37041718.
      View in: PubMed
    38. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 34509475.
      View in: PubMed
    39. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 10217437.
      View in: PubMed
    40. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 14557241.
      View in: PubMed
    41. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 14568894.
      View in: PubMed
    42. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 15199155.
      View in: PubMed
    43. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 15596566.
      View in: PubMed
    44. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 24091715.
      View in: PubMed
    45. Li J, Lu D, Dou H, Liu H, Weaver K, Wang W, Li J, Yeh ETH, Williams BO, Zheng L, Yang T. Publisher Correction: Desumoylase SENP6 maintains osteochondroprogenitor homeostasis by suppressing the p53 pathway. Nat Commun. 2018 02 08; 9(1):646. PMID: 29422621.
      View in: PubMed
    46. Lao Y, Yang K, Wang Z, Sun X, Zou Q, Yu X, Cheng J, Tong X, Yeh ETH, Yang J, Yi J. DeSUMOylation of MKK7 kinase by the SUMO2/3 protease SENP3 potentiates lipopolysaccharide-induced inflammatory signaling in macrophages. J Biol Chem. 2018 03 16; 293(11):3965-3980. PMID: 29352108.
      View in: PubMed
    47. Chang HM, Moudgil R, Scarabelli T, Okwuosa TM, Yeh ETH. Cardiovascular Complications of Cancer?Therapy: Best Practices in Diagnosis, Prevention, and Management: Part 1. J Am Coll Cardiol. 2017 Nov 14; 70(20):2536-2551. PMID: 29145954.
      View in: PubMed
    48. Yeh ETH, Chang HM. Cancer and Clot: Between a Rock and a Hard Place. J Am Coll Cardiol. 2017 08 22; 70(8):939-941. PMID: 28818203.
      View in: PubMed
    49. Wang R, Liu F, Zhao Y, Wu D, Chen L, Yeh ETH, Huang C. Reversible regulation of ORC2 SUMOylation by PIAS4 and SENP2. Oncotarget. 2017 Sep 19; 8(41):70142-70155. PMID: 29050267.
      View in: PubMed
    50. Chang HM, Yeh ETH. Potential of Oncocardiology-Reply. JAMA Cardiol. 2017 07 01; 2(7):818. PMID: 28273313.
      View in: PubMed
    51. Bawa-Khalfe T, Yang FM, Ritho J, Lin HK, Cheng J, Yeh ET. SENP1 regulates PTEN stability to dictate prostate cancer development. Oncotarget. 2017 Mar 14; 8(11):17651-17664. PMID: 27852060.
      View in: PubMed
    52. Abe J, Martin JF, Yeh ET. The Future of Onco-Cardiology: We Are Not Just "Side Effect Hunters". Circ Res. 2016 09 30; 119(8):896-9. PMID: 27688305.
      View in: PubMed
    53. Lenihan DJ, Stevens PL, Massey M, Plana JC, Araujo DM, Fanale MA, Fayad LE, Fisch MJ, Yeh ET. The Utility of Point-of-Care Biomarkers to Detect Cardiotoxicity During Anthracycline Chemotherapy: A Feasibility Study. J Card Fail. 2016 Jun; 22(6):433-8. PMID: 27079675.
      View in: PubMed
    54. Moudgil R, Yeh ET. Mechanisms of Cardiotoxicity of Cancer Chemotherapeutic Agents: Cardiomyopathy and Beyond. Can J Cardiol. 2016 07; 32(7):863-870.e5. PMID: 27117975.
      View in: PubMed
    55. Ferdaoussi M, Dai X, Jensen MV, Wang R, Peterson BS, Huang C, Ilkayeva O, Smith N, Miller N, Hajmrle C, Spigelman AF, Wright RC, Plummer G, Suzuki K, Mackay JP, van de Bunt M, Gloyn AL, Ryan TE, Norquay LD, Brosnan MJ, Trimmer JK, Rolph TP, Kibbey RG, Manning Fox JE, Colmers WF, Shirihai OS, Neufer PD, Yeh ET, Newgard CB, MacDonald PE. Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional ? cells. J Clin Invest. 2015 Oct 01; 125(10):3847-60. PMID: 26389676.
      View in: PubMed
    56. Ritho J, Arold ST, Yeh ET. A Critical SUMO1 Modification of LKB1 Regulates AMPK Activity during Energy Stress. Cell Rep. 2015 Aug 04; 12(5):734-42. PMID: 26212320.
      View in: PubMed
    57. Cai R, Gu J, Sun H, Liu X, Mei W, Qi Y, Xue S, Ren S, Rabinowitz JE, Wang Y, Yeh ET, Cheng J. Induction of SENP1 in myocardium contributes to abnormities of mitochondria and cardiomyopathy. J Mol Cell Cardiol. 2015 Feb; 79:115-22. PMID: 25446185.
      View in: PubMed
    58. Qi Y, Wang J, Bomben VC, Li DP, Chen SR, Sun H, Xi Y, Reed JG, Cheng J, Pan HL, Noebels JL, Yeh ET. Hyper-SUMOylation of the Kv7 potassium channel diminishes the M-current leading to seizures and sudden death. Neuron. 2014 Sep 03; 83(5):1159-71. PMID: 25189211.
      View in: PubMed
    59. Vejpongsa P, Yeh ET. Prevention of anthracycline-induced cardiotoxicity: challenges and opportunities. J Am Coll Cardiol. 2014 Sep 02; 64(9):938-45. PMID: 25169180.
      View in: PubMed
    60. Ren YH, Liu KJ, Wang M, Yu YN, Yang K, Chen Q, Yu B, Wang W, Li QW, Wang J, Hou ZY, Fang JY, Yeh ET, Yang J, Yi J. De-SUMOylation of FOXC2 by SENP3 promotes the epithelial-mesenchymal transition in gastric cancer cells. Oncotarget. 2014 Aug 30; 5(16):7093-104. PMID: 25216525.
      View in: PubMed
    61. Ewer M, Gianni L, Pane F, Sandri MT, Steiner RK, Wojnowski L, Yeh ET, Carver JR, Lipshultz SE, Minotti G, Armstrong GT, Cardinale D, Colan SD, Darby SC, Force TL, Kremer LC, Lenihan DJ, Sallan SE, Sawyer DB, Suter TM, Swain SM, van Leeuwen FE. Report on the international colloquium on cardio-oncology (rome, 12-14 march 2014). Ecancermedicalscience. 2014; 8:433. PMID: 24932213.
      View in: PubMed
    62. Vejpongsa P, Yeh ET. Wrestling with heart failure: SUMO-1 to the rescue. Circ Res. 2014 May 09; 114(10):1561-3. PMID: 24812349.
      View in: PubMed
    63. Simari RD, Pepine CJ, Traverse JH, Henry TD, Bolli R, Spoon DB, Yeh E, Hare JM, Schulman IH, Anderson RD, Lambert C, Sayre SL, Taylor DA, Ebert RF, Moy? LA. Bone marrow mononuclear cell therapy for acute myocardial infarction: a perspective from the cardiovascular cell therapy research network. Circ Res. 2014 May 09; 114(10):1564-8. PMID: 24812350.
      View in: PubMed
    64. Said R, Banchs J, Wheler J, Hess KR, Falchook G, Fu S, Naing A, Hong D, Piha-Paul S, Ye Y, Yeh E, Wolff RA, Tsimberidou AM. The prognostic significance of left ventricular ejection fraction in patients with advanced cancer treated in phase I clinical trials. Ann Oncol. 2014 Jan; 25(1):276-82. PMID: 24356639.
      View in: PubMed
    65. Ky B, Vejpongsa P, Yeh ET, Force T, Moslehi JJ. Emerging paradigms in cardiomyopathies associated with cancer therapies. Circ Res. 2013 Aug 30; 113(6):754-64. PMID: 23989717.
      View in: PubMed
    66. Heo KS, Chang E, Le NT, Cushman H, Yeh ET, Fujiwara K, Abe J. De-SUMOylation enzyme of sentrin/SUMO-specific protease 2 regulates disturbed flow-induced SUMOylation of ERK5 and p53 that leads to endothelial dysfunction and atherosclerosis. Circ Res. 2013 Mar 15; 112(6):911-23. PMID: 23381569.
      View in: PubMed
    67. Lee YC, Jin JK, Cheng CJ, Huang CF, Song JH, Huang M, Brown WS, Zhang S, Yu-Lee LY, Yeh ET, McIntyre BW, Logothetis CJ, Gallick GE, Lin SH. Targeting constitutively activated ?1 integrins inhibits prostate cancer metastasis. Mol Cancer Res. 2013 Apr; 11(4):405-17. PMID: 23339185.
      View in: PubMed
    68. Cai R, Yu T, Huang C, Xia X, Liu X, Gu J, Xue S, Yeh ET, Cheng J. SUMO-specific protease 1 regulates mitochondrial biogenesis through PGC-1a. J Biol Chem. 2012 Dec 28; 287(53):44464-70. PMID: 23152500.
      View in: PubMed
    69. Zhang S, Liu X, Bawa-Khalfe T, Lu LS, Lyu YL, Liu LF, Yeh ET. Identification of the molecular basis of doxorubicin-induced cardiotoxicity. Nat Med. 2012 Nov; 18(11):1639-42. PMID: 23104132.
      View in: PubMed
    70. Willerson JT, Yeh ET, Perin EC. Cytokine profile and ST-elevation myocardial infarction. Circ Res. 2012 Oct 26; 111(10):1256-7. PMID: 23104875.
      View in: PubMed
    71. Bawa-Khalfe T, Lu LS, Zuo Y, Huang C, Dere R, Lin FM, Yeh ET. Differential expression of SUMO-specific protease 7 variants regulates epithelial-mesenchymal transition. Proc Natl Acad Sci U S A. 2012 Oct 23; 109(43):17466-71. PMID: 23045645.
      View in: PubMed
    72. Yeh ET, Willerson JT. Heparin and bone marrow-derived cell therapy: friend or foe? Circ Res. 2012 Sep 14; 111(7):819-20. PMID: 22982868.
      View in: PubMed
    73. Wang Q, Xia N, Li T, Xu Y, Zou Y, Zuo Y, Fan Q, Bawa-Khalfe T, Yeh ET, Cheng J. SUMO-specific protease 1 promotes prostate cancer progression and metastasis. Oncogene. 2013 May 09; 32(19):2493-8. PMID: 22733136.
      View in: PubMed
    74. Yeh ET. Microphthalmia-associated transcription factor, melanoma, and renal carcinoma: the small ubiquitin-like modifier connection. Pigment Cell Melanoma Res. 2011 Dec; 24(6):1079-80. PMID: 22216437.
      View in: PubMed
    75. Yeh ET, Lau SC, Su WJ, Tsai DJ, Tu YY, Lai YL. An examination of cancer-related fatigue through proposed diagnostic criteria in a sample of cancer patients in Taiwan. BMC Cancer. 2011 Sep 06; 11:387. PMID: 21896191.
      View in: PubMed
    76. Lin FM, Yeh ET. Balancing act during development: lessons from a SUMO-less SF-1. Dev Cell. 2011 Aug 16; 21(2):191-2. PMID: 21839916.
      View in: PubMed
    77. Chen CT, Yamaguchi H, Lee HJ, Du Y, Lee HH, Xia W, Yu WH, Hsu JL, Yen CJ, Sun HL, Wang Y, Yeh ET, Hortobagyi GN, Hung MC. Dual targeting of tumor angiogenesis and chemotherapy by endostatin-cytosine deaminase-uracil phosphoribosyltransferase. Mol Cancer Ther. 2011 Aug; 10(8):1327-36. PMID: 21610170.
      View in: PubMed
    78. McGoogan KE, Haafiz AB, Gonz?lez Peralta RP. Herpes simplex virus hepatitis in infants: clinical outcomes and correlates of disease severity. J Pediatr. 2011 Oct; 159(4):608-11. PMID: 21470166.
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    188. Pan YT, Kamitani T, Bhuvaneswaran C, Hallaq Y, Warren CD, Yeh ET, Elbein AD. Inhibition of glycosylphosphatidylinositol anchor formation by mannosamine. J Biol Chem. 1992 Oct 15; 267(29):21250-5. PMID: 1400435.
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    189. Yeh ET, Chang HM. Pathophysiology and principles of pain management in rheumatic diseases. Curr Opin Rheumatol. 1992 Jun; 4(3):332-6. PMID: 1599812.
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    190. Urakaze M, Kamitani T, DeGasperi R, Sugiyama E, Chang HM, Warren CD, Yeh ET. Identification of a missing link in glycosylphosphatidylinositol anchor biosynthesis in mammalian cells. J Biol Chem. 1992 Apr 05; 267(10):6459-62. PMID: 1313004.
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    191. Thomas LJ, Urakaze M, DeGasperi R, Kamitani T, Sugiyama E, Chang HM, Warren CD, Yeh ET. Differential expression of glycosylphosphatidylinositol-anchored proteins in a murine T cell hybridoma mutant producing limiting amounts of the glycolipid core. Implications for paroxysmal nocturnal hemoglobinuria. J Clin Invest. 1992 Apr; 89(4):1172-7. PMID: 1532587.
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    192. Zietman AL, Sugiyama E, Ramsay JR, Silobrcic V, Yeh ET, Sedlacek RS, Suit HD. A comparative study on the xenotransplantability of human solid tumors into mice with different genetic immune deficiencies. Int J Cancer. 1991 Mar 12; 47(5):755-9. PMID: 2004856.
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    193. Yeh E, Driscoll R, Coltrera M, Olins A, Bloom K. A dynamin-like protein encoded by the yeast sporulation gene SPO15. Nature. 1991 Feb 21; 349(6311):713-5. PMID: 1825352.
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    194. Sugiyama E, Cantagrel A, Reno T, Stafford-Brady F, Yeh ET, Bonventre JV. Selection of T cell receptor expression mutants through the functionally linked Ly-6A. Cell Immunol. 1990 Oct 15; 130(2):271-80. PMID: 1976441.
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    195. Yeh ET, Reiser H, Bamezai A, Rock KL. TAP transcription and phosphatidylinositol linkage mutants are defective in activation through the T cell receptor. Cell. 1988 Mar 11; 52(5):665-74. PMID: 2894252.
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    196. Reiser H, Oettgen H, Yeh ET, Terhorst C, Low MG, Benacerraf B, Rock KL. Structural characterization of the TAP molecule: a phosphatidylinositol-linked glycoprotein distinct from the T cell receptor/T3 complex and Thy-1. Cell. 1986 Nov 07; 47(3):365-70. PMID: 2876780.
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    197. Yeh ET, Reiser H, Benacerraf B, Rock KL. The expression, function, and ontogeny of a novel T cell-activating protein, TAP, in the thymus. J Immunol. 1986 Aug 15; 137(4):1232-8. PMID: 2426356.
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    198. Rock KL, Yeh ET, Gramm CF, Haber SI, Reiser H, Benacerraf B. TAP, a novel T cell-activating protein involved in the stimulation of MHC-restricted T lymphocytes. J Exp Med. 1986 Feb 01; 163(2):315-33. PMID: 2418146.
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    199. Yeh ET, Benacerraf B, Rock KL. Analysis of thymocyte MHC specificity with thymocyte hybridomas. J Exp Med. 1984 Sep 01; 160(3):799-813. PMID: 6206189.
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