 Receptors, Opioid, kappa
"Receptors, Opioid, kappa" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of opioid receptors recognized by its pharmacological profile. Kappa opioid receptors bind dynorphins with a higher affinity than endorphins which are themselves preferred to enkephalins.
| Descriptor ID |
D017473
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| MeSH Number(s) |
D12.776.543.750.100.620.400 D12.776.543.750.720.600.610.400 D12.776.543.750.750.555.610.400
|
| Concept/Terms |
Receptors, Opioid, kappa- Receptors, Opioid, kappa
- Opioid Receptors, kappa
- kappa Opioid Receptors
- Receptors, kappa Opioid
- Receptors, kappa
- kappa Receptor
- Receptor, kappa
- kappa Receptors
- kappa Opioid Receptor
- Opioid Receptor, kappa
- Receptor, kappa Opioid
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Opioid, kappa".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.100]
- Receptors, Opioid [D12.776.543.750.100.620]
- Receptors, Opioid, kappa [D12.776.543.750.100.620.400]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Neuropeptide [D12.776.543.750.720.600]
- Receptors, Opioid [D12.776.543.750.720.600.610]
- Receptors, Opioid, kappa [D12.776.543.750.720.600.610.400]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Neuropeptide [D12.776.543.750.750.555]
- Receptors, Opioid [D12.776.543.750.750.555.610]
- Receptors, Opioid, kappa [D12.776.543.750.750.555.610.400]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Opioid, kappa".
This graph shows the total number of publications written about "Receptors, Opioid, kappa" by people in UAMS Profiles by year, and whether "Receptors, Opioid, kappa" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2020 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 | | 2016 | 1 | 1 | 2 | | 2013 | 2 | 0 | 2 | | 2012 | 2 | 1 | 3 | | 2011 | 3 | 1 | 4 | | 2010 | 2 | 0 | 2 | | 2009 | 1 | 0 | 1 | | 2008 | 3 | 0 | 3 | | 2007 | 3 | 0 | 3 | | 2006 | 1 | 1 | 2 | | 2005 | 4 | 1 | 5 | | 2002 | 0 | 1 | 1 | | 1998 | 0 | 1 | 1 | | 1989 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptors, Opioid, kappa" by people in Profiles over the past ten years.
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Slavov S, Mattes W, Beger RD. Determination of structural factors affecting binding to mu, kappa and delta opioid receptors. Arch Toxicol. 2020 04; 94(4):1215-1227.
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Lake EP, Mitchell BG, Shorter DI, Kosten T, Domingo CB, Walder AM. Buprenorphine for the treatment of posttraumatic stress disorder. Am J Addict. 2019 02; 28(2):86-91.
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Wells AM, Ridener E, Bourbonais CA, Kim W, Pantazopoulos H, Carroll FI, Kim KS, Cohen BM, Carlezon WA. Effects of Chronic Social Defeat Stress on Sleep and Circadian Rhythms Are Mitigated by Kappa-Opioid Receptor Antagonism. J Neurosci. 2017 08 09; 37(32):7656-7668.
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Owens SM, Pollard GT, Howard JL, Fennell TR, Snyder RW, Carroll FI. Pharmacodynamic Relationships between Duration of Action of JDTic-like Kappa-Opioid Receptor Antagonists and Their Brain and Plasma Pharmacokinetics in Rats. ACS Chem Neurosci. 2016 12 21; 7(12):1737-1745.
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Yadlapalli JSK, Ford BM, Ketkar A, Wan A, Penthala NR, Eoff RL, Prather PL, Dobretsov M, Crooks PA. Antinociceptive effects of the 6-O-sulfate ester of morphine in normal and diabetic rats: Comparative role of mu- and delta-opioid receptors. Pharmacol Res. 2016 11; 113(Pt A):335-347.
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Munro TA, Huang XP, Inglese C, Perrone MG, Van't Veer A, Carroll FI, Béguin C, Carlezon WA, Colabufo NA, Cohen BM, Roth BL. Selective ? opioid antagonists nor-BNI, GNTI and JDTic have low affinities for non-opioid receptors and transporters. PLoS One. 2013; 8(8):e70701.
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Van't Veer A, Bechtholt AJ, Onvani S, Potter D, Wang Y, Liu-Chen LY, Schütz G, Chartoff EH, Rudolph U, Cohen BM, Carlezon WA. Ablation of kappa-opioid receptors from brain dopamine neurons has anxiolytic-like effects and enhances cocaine-induced plasticity. Neuropsychopharmacology. 2013 Jul; 38(8):1585-97.
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