 Receptors, Opioid, kappa
"Receptors, Opioid, kappa" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of opioid receptors recognized by its pharmacological profile. Kappa opioid receptors bind dynorphins with a higher affinity than endorphins which are themselves preferred to enkephalins.
| Descriptor ID |
D017473
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| MeSH Number(s) |
D12.776.543.750.100.620.400 D12.776.543.750.720.600.610.400 D12.776.543.750.750.555.610.400
|
| Concept/Terms |
Receptors, Opioid, kappa- Receptors, Opioid, kappa
- Opioid Receptors, kappa
- kappa Opioid Receptors
- Receptors, kappa Opioid
- Receptors, kappa
- kappa Receptor
- Receptor, kappa
- kappa Receptors
- kappa Opioid Receptor
- Opioid Receptor, kappa
- Receptor, kappa Opioid
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Opioid, kappa".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.100]
- Receptors, Opioid [D12.776.543.750.100.620]
- Receptors, Opioid, kappa [D12.776.543.750.100.620.400]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Neuropeptide [D12.776.543.750.720.600]
- Receptors, Opioid [D12.776.543.750.720.600.610]
- Receptors, Opioid, kappa [D12.776.543.750.720.600.610.400]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Neuropeptide [D12.776.543.750.750.555]
- Receptors, Opioid [D12.776.543.750.750.555.610]
- Receptors, Opioid, kappa [D12.776.543.750.750.555.610.400]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Opioid, kappa".
This graph shows the total number of publications written about "Receptors, Opioid, kappa" by people in UAMS Profiles by year, and whether "Receptors, Opioid, kappa" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2019 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 | | 2016 | 1 | 1 | 2 | | 2013 | 2 | 0 | 2 | | 2012 | 2 | 1 | 3 | | 2011 | 3 | 1 | 4 | | 2010 | 2 | 0 | 2 | | 2009 | 1 | 0 | 1 | | 2008 | 3 | 0 | 3 | | 2007 | 3 | 0 | 3 | | 2006 | 1 | 1 | 2 | | 2005 | 4 | 1 | 5 | | 2002 | 0 | 1 | 1 | | 1998 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptors, Opioid, kappa" by people in Profiles over the past ten years.
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Lake EP, Mitchell BG, Shorter DI, Kosten T, Domingo CB, Walder AM. Buprenorphine for the treatment of posttraumatic stress disorder. Am J Addict. 2019 02; 28(2):86-91.
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Wells AM, Ridener E, Bourbonais CA, Kim W, Pantazopoulos H, Carroll FI, Kim KS, Cohen BM, Carlezon WA. Effects of Chronic Social Defeat Stress on Sleep and Circadian Rhythms Are Mitigated by Kappa-Opioid Receptor Antagonism. J Neurosci. 2017 08 09; 37(32):7656-7668.
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Owens SM, Pollard GT, Howard JL, Fennell TR, Snyder RW, Carroll FI. Pharmacodynamic Relationships between Duration of Action of JDTic-like Kappa-Opioid Receptor Antagonists and Their Brain and Plasma Pharmacokinetics in Rats. ACS Chem Neurosci. 2016 12 21; 7(12):1737-1745.
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Yadlapalli JSK, Ford BM, Ketkar A, Wan A, Penthala NR, Eoff RL, Prather PL, Dobretsov M, Crooks PA. Antinociceptive effects of the 6-O-sulfate ester of morphine in normal and diabetic rats: Comparative role of mu- and delta-opioid receptors. Pharmacol Res. 2016 11; 113(Pt A):335-347.
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Munro TA, Huang XP, Inglese C, Perrone MG, Van't Veer A, Carroll FI, Béguin C, Carlezon WA, Colabufo NA, Cohen BM, Roth BL. Selective ? opioid antagonists nor-BNI, GNTI and JDTic have low affinities for non-opioid receptors and transporters. PLoS One. 2013; 8(8):e70701.
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Van't Veer A, Bechtholt AJ, Onvani S, Potter D, Wang Y, Liu-Chen LY, Schütz G, Chartoff EH, Rudolph U, Cohen BM, Carlezon WA. Ablation of kappa-opioid receptors from brain dopamine neurons has anxiolytic-like effects and enhances cocaine-induced plasticity. Neuropsychopharmacology. 2013 Jul; 38(8):1585-97.
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Van't Veer A, Yano JM, Carroll FI, Cohen BM, Carlezon WA. Corticotropin-releasing factor (CRF)-induced disruption of attention in rats is blocked by the ?-opioid receptor antagonist JDTic. Neuropsychopharmacology. 2012 Dec; 37(13):2809-16.
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Ranganathan M, Schnakenberg A, Skosnik PD, Cohen BM, Pittman B, Sewell RA, D'Souza DC. Dose-related behavioral, subjective, endocrine, and psychophysiological effects of the ? opioid agonist Salvinorin A in humans. Biol Psychiatry. 2012 Nov 15; 72(10):871-9.
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Munro TA, Berry LM, Van't Veer A, Béguin C, Carroll FI, Zhao Z, Carlezon WA, Cohen BM. Long-acting ? opioid antagonists nor-BNI, GNTI and JDTic: pharmacokinetics in mice and lipophilicity. BMC Pharmacol. 2012 May 29; 12:5.
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Béguin C, Potuzak J, Xu W, Liu-Chen LY, Streicher JM, Groer CE, Bohn LM, Carlezon WA, Cohen BM. Differential signaling properties at the kappa opioid receptor of 12-epi-salvinorin A and its analogues. Bioorg Med Chem Lett. 2012 Jan 15; 22(2):1023-6.
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Wessinger WD, Li M, McMillan DE. Drug discrimination in pigeons trained to discriminate among morphine, U50488, a combination of these drugs, and saline. Behav Pharmacol. 2011 Sep; 22(5-6):468-79.
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Melief EJ, Miyatake M, Carroll FI, Béguin C, Carlezon WA, Cohen BM, Grimwood S, Mitch CH, Rorick-Kehn L, Chavkin C. Duration of action of a broad range of selective ?-opioid receptor antagonists is positively correlated with c-Jun N-terminal kinase-1 activation. Mol Pharmacol. 2011 Nov; 80(5):920-9.
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Potter DN, Damez-Werno D, Carlezon WA, Cohen BM, Chartoff EH. Repeated exposure to the ?-opioid receptor agonist salvinorin A modulates extracellular signal-regulated kinase and reward sensitivity. Biol Psychiatry. 2011 Oct 15; 70(8):744-53.
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Mendelson JE, Coyle JR, Lopez JC, Baggott MJ, Flower K, Everhart ET, Munro TA, Galloway GP, Cohen BM. Lack of effect of sublingual salvinorin A, a naturally occurring kappa opioid, in humans: a placebo-controlled trial. Psychopharmacology (Berl). 2011 Apr; 214(4):933-9.
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