Depressive Disorder, Major
"Depressive Disorder, Major" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Marked depression appearing in the involution period and characterized by hallucinations, delusions, paranoia, and agitation.
Descriptor ID |
D003865
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MeSH Number(s) |
F03.600.300.375
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Concept/Terms |
Depressive Disorder, Major- Depressive Disorder, Major
- Depressive Disorders, Major
- Disorder, Major Depressive
- Disorders, Major Depressive
- Major Depressive Disorders
- Major Depressive Disorder
Depression, Involutional- Depression, Involutional
- Involutional Depression
- Melancholia, Involutional
- Involutional Melancholia
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Below are MeSH descriptors whose meaning is more general than "Depressive Disorder, Major".
Below are MeSH descriptors whose meaning is more specific than "Depressive Disorder, Major".
This graph shows the total number of publications written about "Depressive Disorder, Major" by people in UAMS Profiles by year, and whether "Depressive Disorder, Major" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2024 | 3 | 0 | 3 | 2023 | 2 | 0 | 2 | 2022 | 5 | 0 | 5 | 2021 | 5 | 0 | 5 | 2020 | 1 | 2 | 3 | 2019 | 5 | 0 | 5 | 2018 | 5 | 0 | 5 | 2017 | 3 | 1 | 4 | 2016 | 3 | 0 | 3 | 2015 | 1 | 0 | 1 | 2014 | 4 | 1 | 5 | 2013 | 2 | 0 | 2 | 2012 | 4 | 2 | 6 | 2011 | 1 | 1 | 2 | 2010 | 4 | 0 | 4 | 2009 | 3 | 0 | 3 | 2008 | 0 | 1 | 1 | 2007 | 1 | 0 | 1 | 2006 | 4 | 0 | 4 | 2005 | 10 | 0 | 10 | 2004 | 2 | 0 | 2 | 2003 | 6 | 0 | 6 | 2002 | 4 | 0 | 4 | 2000 | 1 | 1 | 2 | 1999 | 1 | 0 | 1 |
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Below are the most recent publications written about "Depressive Disorder, Major" by people in Profiles over the past ten years.
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Sultan AA, Goldstein BI, Blanco C, Kennedy KG, Conway KP, He JP, Merikangas K. Correlates of cannabis use and cannabis use disorder among adolescents with major depressive disorder and bipolar disorder in the National Comorbidity Survey-Adolescent Supplement (NCS-A). J Affect Disord. 2025 Feb 15; 371:268-278.
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Collins AC, Lekkas D, Struble CA, Trudeau BM, Jewett AD, Griffin TZ, Nemesure MD, Price GD, Heinz MV, Nepal S, Pillai A, Mackin DM, Campbell AT, Budney AJ, Jacobson NC. From mood to use: Using ecological momentary assessments to examine how anhedonia and depressed mood impact cannabis use in a depressed sample. Psychiatry Res. 2024 Sep; 339:116110.
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Ironside M, Duda JM, Moser AD, Holsen LM, Zuo CS, Du F, Perlo S, Richards CE, Chen X, Nickerson LD, Null KE, Esfand SM, Alexander MM, Crowley DJ, Lauze M, Misra M, Goldstein JM, Pizzagalli DA. Association of Lower Rostral Anterior Cingulate GABA+ and Dysregulated Cortisol Stress Response With Altered Functional Connectivity in Young Adults With Lifetime Depression: A Multimodal Imaging Investigation of Trait and State Effects. Am J Psychiatry. 2024 Jul 01; 181(7):639-650.
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Beaussant Y, Tarbi E, Nigam K, Miner S, Sager Z, Sanders JJ, Ljuslin M, Gu?rin B, Thambi P, Tulsky JA, Agrawal M. Acceptability of psilocybin-assisted group therapy in patients with cancer and major depressive disorder: Qualitative analysis. Cancer. 2024 04 01; 130(7):1147-1157.
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Na X, Glasier CM, Andres A, Bellando J, Chen H, Gao W, Livingston LW, Badger TM, Ou X. Associations between mother's depressive symptoms during pregnancy and newborn's brain functional connectivity. Cereb Cortex. 2023 07 05; 33(14):8980-8989.
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Barbotin B, Hoertel N, Olfson M, Blanco C, Sanchez-Rico M, Lejoyeux M, Limosin F, Geoffroy PA. Sleep Complaints Among Adults With Major Depressive Episode Are Associated With Increased Risk of Incident Psychiatric Disorders: Results From a Population-Based 3-Year Prospective Study. J Clin Psychiatry. 2022 12 21; 84(1).
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Meador KJ, Stowe ZN, Brown C, Robalino CP, Matthews AG, Kalayjian LA, Voinescu PE, Gerard EE, Penovich P, Gedzelman ER, Cavitt J, Pennell PB. Prospective Cohort Study of Depression During Pregnancy and the Postpartum Period in Women With Epilepsy vs Control Groups. Neurology. 2022 10 11; 99(15):e1573-e1583.
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Oslin DW, Lynch KG, Shih MC, Ingram EP, Wray LO, Chapman SR, Kranzler HR, Gelernter J, Pyne JM, Stone A, DuVall SL, Lehmann LS, Thase ME, Aslam M, Batki SL, Bjork JM, Blow FC, Brenner LA, Chen P, Desai S, Dieperink EW, Fears SC, Fuller MA, Goodman CS, Graham DP, Haas GL, Hamner MB, Helstrom AW, Hurley RA, Icardi MS, Jurjus GJ, Kilbourne AM, Kreyenbuhl J, Lache DJ, Lieske SP, Lynch JA, Meyer LJ, Montalvo C, Muralidhar S, Ostacher MJ, Paschall GY, Pfeiffer PN, Prieto S, Przygodzki RM, Ranganathan M, Rodriguez-Suarez MM, Roggenkamp H, Schichman SA, Schneeweis JS, Simonetti JA, Steinhauer SR, Suppes T, Umbert MA, Vassy JL, Voora D, Wiechers IR, Wood AE. Effect of Pharmacogenomic Testing for Drug-Gene Interactions on Medication Selection and Remission of Symptoms in Major Depressive Disorder: The PRIME Care Randomized Clinical Trial. JAMA. 2022 07 12; 328(2):151-161.
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Han B, Volkow ND, Blanco C, Tipperman D, Einstein EB, Compton WM. Trends in Prevalence of Cigarette Smoking Among US Adults With Major Depression or Substance Use Disorders, 2006-2019. JAMA. 2022 04 26; 327(16):1566-1576.
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Brydges CR, Bhattacharyya S, Dehkordi SM, Milaneschi Y, Penninx B, Jansen R, Kristal BS, Han X, Arnold M, Kastenm?ller G, Bekhbat M, Mayberg HS, Craighead WE, Rush AJ, Fiehn O, Dunlop BW, Kaddurah-Daouk R. Metabolomic and inflammatory signatures of symptom dimensions in major depression. Brain Behav Immun. 2022 05; 102:42-52.
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Katz IR, Rogers MP, Lew R, Thwin SS, Doros G, Ahearn E, Ostacher MJ, DeLisi LE, Smith EG, Ringer RJ, Ferguson R, Hoffman B, Kaufman JS, Paik JM, Conrad CH, Holmberg EF, Boney TY, Huang GD, Liang MH. Lithium Treatment in the Prevention of Repeat Suicide-Related Outcomes in Veterans With Major Depression or Bipolar Disorder: A Randomized Clinical Trial. JAMA Psychiatry. 2022 01 01; 79(1):24-32.
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Kim DJ, Mirmina J, Narine S, Wachtel J, Carbajal JM, Fox H, C?ceda R. Altered physical pain processing in different psychiatric conditions. Neurosci Biobehav Rev. 2022 02; 133:104510.
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Arathimos R, Ronaldson A, Howe LJ, Fabbri C, Hagenaars S, Hotopf M, Gaughran F, Lewis CM, Dregan A. Vitamin D and the risk of treatment-resistant and atypical depression: A Mendelian randomization study. Transl Psychiatry. 2021 11 04; 11(1):561.
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Watson KT, Simard JF, Henderson VW, Nutkiewicz L, Lamers F, Nasca C, Rasgon N, Penninx BWJH. Incident Major Depressive Disorder Predicted by Three Measures of Insulin Resistance: A Dutch Cohort Study. Am J Psychiatry. 2021 10 01; 178(10):914-920.
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Kalra SS, Jaber J, Alzghoul BN, Hyde R, Parikh S, Urbine D, Reddy R. Pre-Existing Psychiatric Illness Is Associated With an Increased Risk of Delirium in Patients With Acute Respiratory Distress Syndrome. J Intensive Care Med. 2022 May; 37(5):647-654.
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Watson KT, Simard JF, Henderson VW, Nutkiewicz L, Lamers F, Rasgon N, Penninx B. Association of Insulin Resistance With Depression Severity and Remission Status: Defining a Metabolic Endophenotype of Depression. JAMA Psychiatry. 2021 04 01; 78(4):439-441.
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MahmoudianDehkordi S, Ahmed AT, Bhattacharyya S, Han X, Baillie RA, Arnold M, Skime MK, John-Williams LS, Moseley MA, Thompson JW, Louie G, Riva-Posse P, Craighead WE, McDonald W, Krishnan R, Rush AJ, Frye MA, Dunlop BW, Weinshilboum RM, Kaddurah-Daouk R. Alterations in acylcarnitines, amines, and lipids inform about the mechanism of action of citalopram/escitalopram in major depression. Transl Psychiatry. 2021 03 02; 11(1):153.
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Rosoff DB, Smith GD, Lohoff FW. Prescription Opioid Use and Risk for Major Depressive Disorder and Anxiety and Stress-Related Disorders: A Multivariable Mendelian Randomization Analysis. JAMA Psychiatry. 2021 02 01; 78(2):151-160.
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Worley LLM, Wise-Ehlers A. Telepsychiatry in Obstetrics. Obstet Gynecol Clin North Am. 2020 Jun; 47(2):333-340.
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Hayes CJ, Krebs EE, Hudson T, Brown J, Li C, Martin BC. Impact of opioid dose escalation on pain intensity: a retrospective cohort study. Pain. 2020 05; 161(5):979-988.
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Geoffroy PA, Tebeka S, Blanco C, Dubertret C, Le Strat Y. Shorter and longer durations of sleep are associated with an increased twelve-month prevalence of psychiatric and substance use disorders: Findings from a nationally representative survey of US adults (NESARC-III). J Psychiatr Res. 2020 05; 124:34-41.
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Cohen BM. Evidence-Based Drug Treatment of Acute Depression in Bipolar Disorder. JAMA Psychiatry. 2019 12 01; 76(12):1314-1315.
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Jain N, Wan F, Kothari M, Adelodun A, Ware J, Sarode R, Hedayati SS. Association of platelet function with depression and its treatment with sertraline in patients with chronic kidney disease: analysis of a randomized trial. BMC Nephrol. 2019 10 29; 20(1):395.
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Bhattacharyya S, Ahmed AT, Arnold M, Liu D, Luo C, Zhu H, Mahmoudiandehkordi S, Neavin D, Louie G, Dunlop BW, Frye MA, Wang L, Weinshilboum RM, Krishnan RR, Rush AJ, Kaddurah-Daouk R. Metabolomic signature of exposure and response to citalopram/escitalopram in depressed outpatients. Transl Psychiatry. 2019 07 04; 9(1):173.
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Subica AM, Aitaoto N, Link BG, Yamada AM, Henwood BF, Sullivan G. Mental Health Status, Need, and Unmet Need for Mental Health Services Among U.S. Pacific Islanders. Psychiatr Serv. 2019 07 01; 70(7):578-585.
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Goldberg SB, Simpson TL, Lehavot K, Katon JG, Chen JA, Glass JE, Schnurr PP, Sayer NA, Fortney JC. Mental Health Treatment Delay: A Comparison Among Civilians and Veterans of Different Service Eras. Psychiatr Serv. 2019 05 01; 70(5):358-366.
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Messias E, Flynn V. Burnout and Depression: Same Phenomenon or Overlapping Constructs? Response to Bianchi et al. Am J Psychiatry. 2019 01 01; 176(1):79-80.
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Messias E, Flynn V. The Tired, Retired, and Recovered Physician: Professional Burnout Versus Major Depressive Disorder. Am J Psychiatry. 2018 08 01; 175(8):716-719.
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Zubenko GS, Sommer BR, Cohen BM. On the Marketing and Use of Pharmacogenetic Tests for Psychiatric Treatment. JAMA Psychiatry. 2018 08 01; 75(8):769-770.
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C?ceda R, Bush K, James GA, Stowe ZN, Kilts CD. Modes of Resting Functional Brain Organization Differentiate Suicidal Thoughts and Actions: A Preliminary Study. J Clin Psychiatry. 2018 07 10; 79(4).
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Bovin MJ, Miller CJ, Koenig CJ, Lipschitz JM, Zamora KA, Wright PB, Pyne JM, Burgess JF. Veterans' experiences initiating VA-based mental health care. Psychol Serv. 2019 Nov; 16(4):612-620.
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Kumar P, Goer F, Murray L, Dillon DG, Beltzer ML, Cohen AL, Brooks NH, Pizzagalli DA. Impaired reward prediction error encoding and striatal-midbrain connectivity in depression. Neuropsychopharmacology. 2018 06; 43(7):1581-1588.
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Hedayati SS, Gregg LP, Carmody T, Jain N, Toups M, Rush AJ, Toto RD, Trivedi MH. Effect of Sertraline on Depressive Symptoms in Patients With Chronic Kidney Disease Without Dialysis Dependence: The CAST Randomized Clinical Trial. JAMA. 2017 11 21; 318(19):1876-1890.
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Suri R, Stowe ZN, Cohen LS, Newport DJ, Burt VK, Aquino-Elias AR, Knight BT, Mintz J, Altshuler LL. Prospective Longitudinal Study of Predictors of Postpartum-Onset Depression in Women With a History of Major Depressive Disorder. J Clin Psychiatry. 2017 Sep/Oct; 78(8):1110-1116.
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Hudson TJ, Painter JT, Martin BC, Austen MA, Williams JS, Fortney JC, Sullivan MD, Edlund MJ. Pharmacoepidemiologic analyses of opioid use among OEF/OIF/OND veterans. Pain. 2017 06; 158(6):1039-1045.
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Phillips C. Physical Activity Modulates Common Neuroplasticity Substrates in Major Depressive and Bipolar Disorder. Neural Plast. 2017; 2017:7014146.
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Jain N, Carmody T, Minhajuddin AT, Toups M, Trivedi MH, Rush AJ, Hedayati SS. Prognostic Utility of a Self-Reported Depression Questionnaire versus Clinician-Based Assessment on Renal Outcomes. Am J Nephrol. 2016; 44(3):234-44.
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Campbell DG, Bonner LM, Bolkan CR, Lanto AB, Zivin K, Waltz TJ, Klap R, Rubenstein LV, Chaney EF. Stigma Predicts Treatment Preferences and Care Engagement Among Veterans Affairs Primary Care Patients with Depression. Ann Behav Med. 2016 08; 50(4):533-44.
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Chouinard VA, Pingali SM, Chouinard G, Henderson DC, Mallya SG, Cypess AM, Cohen BM, ?ng?r D. Factors associated with overweight and obesity in schizophrenia, schizoaffective and bipolar disorders. Psychiatry Res. 2016 Mar 30; 237:304-10.
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Helton SG, Lohoff FW. Pharmacogenetics of alcohol use disorders and comorbid psychiatric disorders. Psychiatry Res. 2015 Dec 15; 230(2):121-9.
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