 Schizophrenia
"Schizophrenia" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.
| Descriptor ID |
D012559
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| MeSH Number(s) |
F03.700.750
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| Concept/Terms |
Schizophrenia- Schizophrenia
- Schizophrenias
- Schizophrenic Disorders
- Disorder, Schizophrenic
- Disorders, Schizophrenic
- Schizophrenic Disorder
- Dementia Praecox
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Below are MeSH descriptors whose meaning is more general than "Schizophrenia".
Below are MeSH descriptors whose meaning is more specific than "Schizophrenia".
This graph shows the total number of publications written about "Schizophrenia" by people in UAMS Profiles by year, and whether "Schizophrenia" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2025 | 2 | 0 | 2 | | 2024 | 1 | 1 | 2 | | 2023 | 3 | 0 | 3 | | 2022 | 4 | 0 | 4 | | 2021 | 2 | 1 | 3 | | 2020 | 4 | 0 | 4 | | 2019 | 4 | 2 | 6 | | 2018 | 4 | 4 | 8 | | 2017 | 5 | 0 | 5 | | 2016 | 3 | 3 | 6 | | 2015 | 6 | 1 | 7 | | 2014 | 8 | 1 | 9 | | 2013 | 4 | 2 | 6 | | 2012 | 7 | 1 | 8 | | 2011 | 5 | 3 | 8 | | 2010 | 6 | 0 | 6 | | 2009 | 3 | 2 | 5 | | 2008 | 11 | 4 | 15 | | 2007 | 4 | 2 | 6 | | 2006 | 9 | 4 | 13 | | 2005 | 4 | 1 | 5 | | 2004 | 7 | 4 | 11 | | 2003 | 10 | 2 | 12 | | 2002 | 4 | 1 | 5 | | 2001 | 3 | 0 | 3 | | 2000 | 3 | 0 | 3 | | 1999 | 6 | 1 | 7 | | 1998 | 2 | 0 | 2 | | 1997 | 3 | 0 | 3 | | 1996 | 6 | 1 | 7 | | 1995 | 8 | 1 | 9 | | 1994 | 3 | 1 | 4 | | 1993 | 0 | 1 | 1 | | 1992 | 2 | 0 | 2 | | 1991 | 3 | 0 | 3 | | 1990 | 1 | 0 | 1 |
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Below are the most recent publications written about "Schizophrenia" by people in Profiles over the past ten years.
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Yoviene Sykes LA, Levine N, Tayfur SN, Gibbs-Dean T, Hazan H, Imetovski S, James J, Karmani S, Mathis WS, Markovich P, Purushothaman D, Riley S, Tek C, Veillette C, Cahill JD, Giard J, Marracino A, Barrette K, Bozak S, Gregory F, McDermott G, Srihari VH. The STEP Learning Collaborative: A statewide Learning Healthcare System (LHS) for first episode psychosis. Schizophr Res. 2025 Apr; 278:96-108.
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Kaul I, Claxton A, Sawchak S, Sauder C, Brannan SK, Raj E, Ruan S, Konis G, Brown D, Cutler AJ, Marcus R. Safety and Tolerability of Xanomeline and Trospium Chloride in Schizophrenia: Pooled Results From the 5-Week, Randomized, Double-Blind, Placebo-Controlled EMERGENT Trials. J Clin Psychiatry. 2025 Feb 26; 86(1).
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Chouinard VA, Feizi W, Chen X, Ren B, Lewandowski KE, Anderson J, Prete S, Tusuzian E, Cuklanz K, Zhou S, Bolton P, Stein A, Cohen BM, Du F, ?ng?r D. Intranasal Insulin Increases Brain Glutathione and Enhances Antioxidant Capacity in Healthy Participants but Not in Those With Early Psychotic Disorders. Biol Psychiatry Cogn Neurosci Neuroimaging. 2025 Mar; 10(3):286-294.
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Den J, Nelson N, Klimberg VS. Analysis of the incidence and outcomes of breast cancer in women with schizophrenia. Am J Surg. 2025 Jan; 239:116050.
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Walker VG, Harrison TC. Life Course Perspectives of Aging With Schizophrenia Spectrum Disorders in Psychiatric and Long-Term Care Facilities. Gerontologist. 2024 05 01; 64(5).
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Kirkpatrick B, Luther L, Strauss GP. Negative symptoms in the clinic: we treat what we can describe. Br J Psychiatry. 2023 07; 223(1):271-272.
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Kochunov P, Ma Y, Hatch KS, Gao S, Acheson A, Jahanshad N, Thompson PM, Adhikari BM, Bruce H, Van der Vaart A, Chiappelli J, Du X, Sotiras A, Kvarta MD, Ma T, Chen S, Hong LE. Ancestral, Pregnancy, and Negative Early-Life Risks Shape Children's Brain (Dis)similarity to Schizophrenia. Biol Psychiatry. 2023 08 15; 94(4):332-340.
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Agud HN, Padala PR. The Effect of Psychotic Symptoms on Decision-Making Capacity and Its Assessment in a Patient With Schizoaffective Disorder. Prim Care Companion CNS Disord. 2023 02 07; 25(1).
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Cohen BM, Singh T, ?ng?r D, Konstantin GE, Gardner ME. Clinical phenotypes of five patients with psychotic disorders carrying rare schizophrenia-associated loss-of-function variants. Schizophr Res. 2022 Dec; 250:100-103.
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Cohen BM, ?ng?r D, Babb SM, Harris PQ. Diagnostic terms psychiatrists prefer to use for common psychotic and personality disorders. J Psychiatr Res. 2022 11; 155:226-231.
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Nehme R, Pietil?inen O, Artomov M, Tegtmeyer M, Valakh V, Lehtonen L, Bell C, Singh T, Trehan A, Sherwood J, Manning D, Peirent E, Malik R, Guss EJ, Hawes D, Beccard A, Bara AM, Hazelbaker DZ, Zuccaro E, Genovese G, Loboda AA, Neumann A, Lilliehook C, Kuismin O, Hamalainen E, Kurki M, Hultman CM, K?hler AK, Paulo JA, Ganna A, Madison J, Cohen B, McPhie D, Adolfsson R, Perlis R, Dolmetsch R, Farhi S, McCarroll S, Hyman S, Neale B, Barrett LE, Harper W, Palotie A, Daly M, Eggan K. The 22q11.2 region regulates presynaptic gene-products linked to schizophrenia. Nat Commun. 2022 06 27; 13(1):3690.
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Singh T, Poterba T, Curtis D, Akil H, Al Eissa M, Barchas JD, Bass N, Bigdeli TB, Breen G, Bromet EJ, Buckley PF, Bunney WE, Bybjerg-Grauholm J, Byerley WF, Chapman SB, Chen WJ, Churchhouse C, Craddock N, Cusick CM, DeLisi L, Dodge S, Escamilla MA, Eskelinen S, Fanous AH, Faraone SV, Fiorentino A, Francioli L, Gabriel SB, Gage D, Gagliano Taliun SA, Ganna A, Genovese G, Glahn DC, Grove J, Hall MH, H?m?l?inen E, Heyne HO, Holi M, Hougaard DM, Howrigan DP, Huang H, Hwu HG, Kahn RS, Kang HM, Karczewski KJ, Kirov G, Knowles JA, Lee FS, Lehrer DS, Lescai F, Malaspina D, Marder SR, McCarroll SA, McIntosh AM, Medeiros H, Milani L, Morley CP, Morris DW, Mortensen PB, Myers RM, Nordentoft M, O'Brien NL, Olivares AM, Ongur D, Ouwehand WH, Palmer DS, Paunio T, Quested D, Rapaport MH, Rees E, Rollins B, Satterstrom FK, Schatzberg A, Scolnick E, Scott LJ, Sharp SI, Sklar P, Smoller JW, Sobell JL, Solomonson M, Stahl EA, Stevens CR, Suvisaari J, Tiao G, Watson SJ, Watts NA, Blackwood DH, B?rglum AD, Cohen BM, Corvin AP, Esko T, Freimer NB, Glatt SJ, Hultman CM, McQuillin A, Palotie A, Pato CN, Pato MT, Pulver AE, St Clair D, Tsuang MT, Vawter MP, Walters JT, Werge TM, Ophoff RA, Sullivan PF, Owen MJ, Boehnke M, O'Donovan MC, Neale BM, Daly MJ. Rare coding variants in ten genes confer substantial risk for schizophrenia. Nature. 2022 04; 604(7906):509-516.
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Ponirakis G, Ghandi R, Ahmed A, Gad H, Petropoulos IN, Khan A, Elsotouhy A, Vattoth S, Alshawwaf MKM, Khoodoruth MAS, Ramadan M, Bhagat A, Currie J, Mahfoud Z, Al Hamad H, Own A, M Haddad P, Alabdulla M, Malik RA, Woodruff PW. Abnormal corneal nerve morphology and brain volume in patients with schizophrenia. Sci Rep. 2022 02 03; 12(1):1870.
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Buck B, Gagen EC, Halverson TF, Nagendra A, Ludwig KA, Fortney JC. A systematic search and critical review of studies evaluating psychometric properties of patient-reported outcome measures for schizophrenia. J Psychiatr Res. 2022 03; 147:13-23.
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Hwang M, Roh YS, Talero J, Cohen BM, Baker JT, Brady RO, ?ng?r D, Shinn AK. Auditory hallucinations across the psychosis spectrum: Evidence of dysconnectivity involving cerebellar and temporal lobe regions. Neuroimage Clin. 2021; 32:102893.
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Rajani V, Sengar AS, Salter MW. Src and Fyn regulation of NMDA receptors in health and disease. Neuropharmacology. 2021 08 01; 193:108615.
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Das A, Minner R, Krain L, Spollen J. Delirium on clozapine: A tale of friend turned foe-A case report. Int J Psychiatry Med. 2021 11; 56(6):446-458.
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Park GH, Noh H, Shao Z, Ni P, Qin Y, Liu D, Beaudreault CP, Park JS, Abani CP, Park JM, Le DT, Gonzalez SZ, Guan Y, Cohen BM, McPhie DL, Coyle JT, Lanz TA, Xi HS, Yin C, Huang W, Kim HY, Chung S. Activated microglia cause metabolic disruptions in developmental cortical interneurons that persist in interneurons from individuals with schizophrenia. Nat Neurosci. 2020 11; 23(11):1352-1364.
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Padala SP, Dennis RA, Caceda R. Why COVID-19 Is Especially Difficult for Those With Schizophrenia: Reasons and Solutions. Prim Care Companion CNS Disord. 2020 08 27; 22(5).
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Kathuria A, Lopez-Lengowski K, Jagtap SS, McPhie D, Perlis RH, Cohen BM, Karmacharya R. Transcriptomic Landscape and Functional Characterization of Induced Pluripotent Stem Cell-Derived Cerebral Organoids in Schizophrenia. JAMA Psychiatry. 2020 07 01; 77(7):745-754.
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Meltzer HY, Share DB, Jayathilake K, Salomon RM, Lee MA. Lurasidone Improves Psychopathology and Cognition in Treatment-Resistant Schizophrenia. J Clin Psychopharmacol. 2020 May-Jun; 40(3):240-249.
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Kathuria A, Lopez-Lengowski K, Watmuff B, McPhie D, Cohen BM, Karmacharya R. Synaptic deficits in iPSC-derived cortical interneurons in schizophrenia are mediated by NLGN2 and rescued by N-acetylcysteine. Transl Psychiatry. 2019 11 28; 9(1):321.
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Ni P, Noh H, Park GH, Shao Z, Guan Y, Park JM, Yu S, Park JS, Coyle JT, Weinberger DR, Straub RE, Cohen BM, McPhie DL, Yin C, Huang W, Kim HY, Chung S. iPSC-derived homogeneous populations of developing schizophrenia cortical interneurons have compromised mitochondrial function. Mol Psychiatry. 2020 11; 25(11):2873-2888.
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Chouinard VA, Shinn AK, Valeri L, Chouinard PA, Gardner ME, Asan AE, Cohen BM, ?ng?r D. Visual hallucinations associated with multimodal hallucinations, suicide attempts and morbidity of illness in psychotic disorders. Schizophr Res. 2019 06; 208:196-201.
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Ward KR, Featherstone RE, Naschek MJ, Melnychenko O, Banerjee A, Yi J, Gifford RL, Borgmann-Winter KE, Salter MW, Hahn CG, Siegel SJ. Src deficient mice demonstrate behavioral and electrophysiological alterations relevant to psychiatric and developmental disease. Prog Neuropsychopharmacol Biol Psychiatry. 2019 07 13; 93:84-92.
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Shao Z, Noh H, Bin Kim W, Ni P, Nguyen C, Cote SE, Noyes E, Zhao J, Parsons T, Park JM, Zheng K, Park JJ, Coyle JT, Weinberger DR, Straub RE, Berman KF, Apud J, Ongur D, Cohen BM, McPhie DL, Rapoport JL, Perlis RH, Lanz TA, Xi HS, Yin C, Huang W, Hirayama T, Fukuda E, Yagi T, Ghosh S, Eggan KC, Kim HY, Eisenberg LM, Moghadam AA, Stanton PK, Cho JH, Chung S. Dysregulated protocadherin-pathway activity as an intrinsic defect in induced pluripotent stem cell-derived cortical interneurons from subjects with schizophrenia. Nat Neurosci. 2019 02; 22(2):229-242.
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Cole JB, Klein LR, Mullinax SZ, Nordstrom KD, Driver BE, Wilson MP. Study Enrollment When "Preconsent" Is Utilized for a Randomized Clinical Trial of Two Treatments for Acute Agitation in the Emergency Department. Acad Emerg Med. 2019 05; 26(5):559-566.
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McPhie DL, Nehme R, Ravichandran C, Babb SM, Ghosh SD, Staskus A, Kalinowski A, Kaur R, Douvaras P, Du F, Ongur D, Fossati V, Eggan K, Cohen BM. Oligodendrocyte differentiation of induced pluripotent stem cells derived from subjects with schizophrenias implicate abnormalities in development. Transl Psychiatry. 2018 10 23; 8(1):230.
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Zhou TH, Mueller NE, Spencer KM, Mallya SG, Lewandowski KE, Norris LA, Levy DL, Cohen BM, ?ng?r D, Hall MH. Auditory steady state response deficits are associated with symptom severity and poor functioning in patients with psychotic disorder. Schizophr Res. 2018 11; 201:278-286.
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Chekuri L, Mittal D, Ounpraseuth S. Relationship Between Stereotypes, Prejudice, and Social Distancing in a Sample of Health Care Providers. Prim Care Companion CNS Disord. 2018 May 24; 20(3).
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Robicsek O, Ene HM, Karry R, Ytzhaki O, Asor E, McPhie D, Cohen BM, Ben-Yehuda R, Weiner I, Ben-Shachar D. Isolated Mitochondria Transfer Improves Neuronal Differentiation of Schizophrenia-Derived Induced Pluripotent Stem Cells and Rescues Deficits in a Rat Model of the Disorder. Schizophr Bull. 2018 02 15; 44(2):432-442.
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Yuksel C, Yilmaz S, Nesbit A, Carkaxhiu G, Ravichandran C, Salvatore P, Pingali S, Cohen B, Ongur D. Demographic and clinical characteristics associated with a history of bizarre delusions in a cross-diagnostic sample of individuals with psychotic disorders. Asian J Psychiatr. 2018 Jan; 31:82-85.
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Pyne JM, Fischer EP, Mittal D, Owen R. A Patient-Centered Antipsychotic Medication Adherence Intervention: Results From a Randomized Controlled Trial. J Nerv Ment Dis. 2018 02; 206(2):142-148.
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Fantegrossi WE, Wilson CD, Berquist MD. Pro-psychotic effects of synthetic cannabinoids: interactions with central dopamine, serotonin, and glutamate systems. Drug Metab Rev. 2018 Feb; 50(1):65-73.
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Garcia-Rill E, Mahaffey S, Hyde JR, Urbano FJ. Bottom-up gamma maintenance in various disorders. Neurobiol Dis. 2019 08; 128:31-39.
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Spears CA, Jones DM, Weaver SR, Pechacek TF, Eriksen MP. Motives and perceptions regarding electronic nicotine delivery systems (ENDS) use among adults with mental health conditions. Addict Behav. 2018 05; 80:102-109.
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Kim SY, Kaufman MJ, Cohen BM, Jensen JE, Coyle JT, Du F, ?ng?r D. In?Vivo Brain Glycine and Glutamate Concentrations in Patients With First-Episode Psychosis Measured by Echo Time-Averaged Proton Magnetic Resonance Spectroscopy at 4T. Biol Psychiatry. 2018 03 15; 83(6):484-491.
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Ramaker RC, Bowling KM, Lasseigne BN, Hagenauer MH, Hardigan AA, Davis NS, Gertz J, Cartagena PM, Walsh DM, Vawter MP, Jones EG, Schatzberg AF, Barchas JD, Watson SJ, Bunney BG, Akil H, Bunney WE, Li JZ, Cooper SJ, Myers RM. Post-mortem molecular profiling of three psychiatric disorders. Genome Med. 2017 07 28; 9(1):72.
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Rabin RA, Kozak K, Zakzanis KK, Remington G, Stefan C, Budney AJ, George TP. A method to achieve extended cannabis abstinence in cannabis dependent patients with schizophrenia and non-psychiatric controls. Schizophr Res. 2018 04; 194:47-54.
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Ravichandran C, Shinn AK, ?ng?r D, Perlis RH, Cohen B. Frequency of non-right-handedness in bipolar disorder and schizophrenia. Psychiatry Res. 2017 07; 253:267-269.
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Chouinard VA, Kim SY, Valeri L, Yuksel C, Ryan KP, Chouinard G, Cohen BM, Du F, ?ng?r D. Brain bioenergetics and redox state measured by 31P magnetic resonance spectroscopy in unaffected siblings of patients with psychotic disorders. Schizophr Res. 2017 09; 187:11-16.
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Kirchner JE, Woodward EN, Smith JL, Curran GM, Kilbourne AM, Owen RR, Bauer MS. Implementation Science Supports Core Clinical Competencies: An Overview and Clinical Example. Prim Care Companion CNS Disord. 2016 Dec 08; 18(6).
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Huang JH, Park H, Iaconelli J, Berkovitch SS, Watmuff B, McPhie D, ?ng?r D, Cohen BM, Clish CB, Karmacharya R. Unbiased Metabolite Profiling of Schizophrenia Fibroblasts under Stressful Perturbations Reveals Dysregulation of Plasmalogens and Phosphatidylcholines. J Proteome Res. 2017 02 03; 16(2):481-493.
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Olfson M, Wall M, Wang S, Crystal S, Liu SM, Gerhard T, Blanco C. Short-term Suicide Risk After Psychiatric Hospital Discharge. JAMA Psychiatry. 2016 Nov 01; 73(11):1119-1126.
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Kim SY, Cohen BM, Chen X, Lukas SE, Shinn AK, Yuksel AC, Li T, Du F, ?ng?r D. Redox Dysregulation in Schizophrenia Revealed by in vivo NAD+/NADH Measurement. Schizophr Bull. 2017 01; 43(1):197-204.
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Wilson MP, Vilke GM, Hayden SR, Nordstrom K. Psychiatric Emergencies for Clinicians: Emergency Department Management of Neuroleptic Malignant Syndrome. J Emerg Med. 2016 Jul; 51(1):66-9.
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Chouinard VA, Pingali SM, Chouinard G, Henderson DC, Mallya SG, Cypess AM, Cohen BM, ?ng?r D. Factors associated with overweight and obesity in schizophrenia, schizoaffective and bipolar disorders. Psychiatry Res. 2016 Mar 30; 237:304-10.
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Moran LV, Masters GA, Pingali S, Cohen BM, Liebson E, Rajarethinam RP, Ongur D. Prescription stimulant use is associated with earlier onset of psychosis. J Psychiatr Res. 2015 Dec; 71:41-7.
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Mittal D, Ounpraseuth ST, Reaves C, Chekuri L, Han X, Corrigan P, Sullivan G. Providers' Personal and Professional Contact With Persons With Mental Illness: Relationship to Clinical Expectations. Psychiatr Serv. 2016 Jan; 67(1):55-61.
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Sullivan G, Mittal D, Reaves CM, Haynes TF, Han X, Mukherjee S, Morris S, Marsh L, Corrigan PW. Influence of schizophrenia diagnosis on providers' practice decisions. J Clin Psychiatry. 2015 Aug; 76(8):1068-74; quiz 1074.
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