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Search Results to Michael Birrer

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Birrer, Michael

One or more keywords matched the following items that are connected to Birrer, Michael

Item Type	Name
Concept	Protein Kinase C
Concept	Protein Kinases
Concept	Protein-Tyrosine Kinases
Concept	CDC2-CDC28 Kinases
Concept	Cyclin-Dependent Kinase Inhibitor p16
Concept	Mitogen-Activated Protein Kinase 9
Concept	MAP Kinase Signaling System
Concept	Class I Phosphatidylinositol 3-Kinases
Concept	MAP Kinase Kinase 1
Concept	MAP Kinase Kinase 2
Concept	Receptor Protein-Tyrosine Kinases
Concept	MAP Kinase Kinase 4
Concept	Mitogen-Activated Protein Kinase 3
Concept	Glycogen Synthase Kinases
Concept	Cyclin-Dependent Kinase Inhibitor p21
Concept	NM23 Nucleoside Diphosphate Kinases
Concept	Cyclin-Dependent Kinases
Concept	Cyclin-Dependent Kinase 2
Concept	JNK Mitogen-Activated Protein Kinases
Concept	Extracellular Signal-Regulated MAP Kinases
Concept	I-kappa B Kinase
Concept	Phosphatidylinositol 3-Kinases
Concept	MAP Kinase Kinase Kinases
Concept	Mitogen-Activated Protein Kinase Kinases
Concept	Protein Kinase Inhibitors
Concept	Cyclin-Dependent Kinase 4
Concept	Mitogen-Activated Protein Kinase 1
Concept	Calcium-Calmodulin-Dependent Protein Kinases
Concept	Mitogen-Activated Protein Kinases
Concept	Cyclin-Dependent Kinase Inhibitor p27
Concept	Focal Adhesion Protein-Tyrosine Kinases
Concept	TOR Serine-Threonine Kinases
Concept	p38 Mitogen-Activated Protein Kinases
Concept	p21-Activated Kinases
Academic Article	GOG 8020/210: Risk stratification of lymph node metastasis, disease progression and survival using single nucleotide polymorphisms in endometrial cancer: An NRG oncology/gynecologic oncology group study.
Academic Article	p75-Ras-GRF1 is a c-Jun/AP-1 target protein: its up regulation results in increased Ras activity and is necessary for c-Jun-induced nonadherent growth of Rat1a cells.
Academic Article	Tumor mutational analysis of GOG248, a phase II study of temsirolimus or temsirolimus and alternating megestrol acetate and tamoxifen for advanced endometrial cancer (EC): An NRG Oncology/Gynecologic Oncology Group study.
Academic Article	Phase II, 2-stage, 2-arm, PIK3CA mutation stratified trial of MK-2206 in recurrent endometrial cancer.
Academic Article	Calcineurin activates cytoglobin transcription in hypoxic myocytes.
Academic Article	NORE1A tumor suppressor candidate modulates p21CIP1 via p53.
Academic Article	Novel therapeutic targets.
Academic Article	Calcium-dependent FAK/CREB/TNNC1 signalling mediates the effect of stromal MFAP5 on ovarian cancer metastatic potential.
Academic Article	EGF-R regulates MMP function in fibroblasts through MAPK and AP-1 pathways.
Academic Article	Selumetinib in women with recurrent low-grade serous carcinoma of the ovary or peritoneum: an open-label, single-arm, phase 2 study.
Academic Article	Phase II study of the PI3K inhibitor pilaralisib (SAR245408; XL147) in patients with advanced or recurrent endometrial carcinoma.
Academic Article	Cross-talk between JNK/SAPK and ERK/MAPK pathways: sustained activation of JNK blocks ERK activation by mitogenic factors.
Academic Article	Activation of NF-kappaB signaling by inhibitor of NF-kappaB kinase beta increases aggressiveness of ovarian cancer.
Academic Article	A link between histone deacetylase inhibitors and NF- kappaB signaling.
Academic Article	TGF-? modulates ovarian cancer invasion by upregulating CAF-derived versican in the tumor microenvironment.
Academic Article	Cyclooxygenase-2 expression predicts recurrence of cervical dysplasia following loop electrosurgical excision procedure.
Academic Article	Loss of LKB1 and PTEN tumor suppressor genes in the ovarian surface epithelium induces papillary serous ovarian cancer.
Academic Article	Spleen Tyrosine Kinase Confers Paclitaxel Resistance in Ovarian Cancer.
Academic Article	Reversible regulation of the transformed phenotype of ornithine decarboxylase- and ras-overexpressing cells by dominant-negative mutants of c-Jun.
Academic Article	Activation of YAP1 is associated with poor prognosis and response to taxanes in ovarian cancer.
Academic Article	Differential Effects of EGFL6 on Tumor versus Wound Angiogenesis.
Academic Article	Mutation of ERBB2 provides a novel alternative mechanism for the ubiquitous activation of RAS-MAPK in ovarian serous low malignant potential tumors.
Academic Article	Integrative Kinome Profiling Identifies mTORC1/2 Inhibition as Treatment Strategy in Ovarian Clear Cell Carcinoma.
Academic Article	Safety lead-in of the MEK inhibitor trametinib in combination with GSK2141795, an AKT inhibitor, in patients with recurrent endometrial cancer: An NRG Oncology/GOG study.
Academic Article	A randomized phase II non-comparative study of PF-04691502 and gedatolisib (PF-05212384) in patients with recurrent endometrial cancer.
Academic Article	EMR 20006-012: A phase II randomized double-blind placebo controlled trial comparing the combination of pimasertib (MEK inhibitor) with SAR245409 (PI3K inhibitor) to pimasertib alone in patients with previously treated unresectable borderline or low grade ovarian cancer.
Academic Article	Common variation in Nemo-like kinase is associated with risk of ovarian cancer.
Academic Article	The regulation of tumor suppressor genes by oncogenes.
Academic Article	Ovarian cancer: not a borderline issue!
Academic Article	MAPK pathways mediate hyperoxia-induced oncotic cell death in lung epithelial cells.
Academic Article	Minichromosome maintenance (MCM) protein 4 as a marker for proliferation and its clinical and clinicopathological significance in non-small cell lung cancer.
Academic Article	Activity of sorafenib in recurrent ovarian cancer and primary peritoneal carcinomatosis: a gynecologic oncology group trial.
Academic Article	Olaparib and a-specific PI3K inhibitor alpelisib for patients with epithelial ovarian cancer: a dose-escalation and dose-expansion phase 1b trial.
Academic Article	Nuclear P27 expression in benign, borderline (LMP) and invasive tumors of the ovary and its association with prognosis: a gynecologic oncology group study.
Academic Article	Inhibition of AP-1 suppresses cervical cancer cell proliferation and is associated with p21 expression.
Academic Article	Comparison of expression profiles in ovarian epithelium in vivo and ovarian cancer identifies novel candidate genes involved in disease pathogenesis.
Academic Article	Reactive oxygen species mediated apoptosis of esophageal cancer cells induced by marine triprenyl toluquinones and toluhydroquinones.
Academic Article	Cell cycle and related protein.
Academic Article	p21-activated kinase 3 (PAK3) is an AP-1 regulated gene contributing to actin organisation and migration of transformed fibroblasts.
Grant	The Molecular Genetics of Gynecologic Cancers
Academic Article	Transformation by Raf and other oncogenes renders cells differentially sensitive to growth inhibition by a dominant negative c-jun mutant.
Academic Article	Role of c-jun in human myeloid leukemia cell apoptosis induced by pharmacological inhibitors of protein kinase C.
Academic Article	Molecular characterization of adenocarcinoma of the cervix.
Academic Article	Coordinate regulation of stress- and mitogen-activated protein kinases in the apoptotic actions of ceramide and sphingosine.
Academic Article	Inhibition of the mitogen activated protein (MAP) kinase cascade potentiates cell killing by low dose ionizing radiation in A431 human squamous carcinoma cells.
Academic Article	RRR-alpha-tocopheryl succinate induction of prolonged activation of c-jun amino-terminal kinase and c-jun during induction of apoptosis in human MDA-MB-435 breast cancer cells.
Academic Article	JunB forms the majority of the AP-1 complex and is a target for redox regulation by receptor tyrosine kinase and G protein-coupled receptor agonists in smooth muscle cells.
Academic Article	Mechanism of action of a dominant-negative mutant of c-Jun.
Academic Article	Cooperation between retinoic acid and phorbol esters enhances human teratocarcinoma differentiation.
Academic Article	Regulation of urokinase-type plasminogen activator expression by the v-mos oncogene.
Academic Article	Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.
Academic Article	The Jun kinase/stress-activated protein kinase pathway functions to regulate DNA repair and inhibition of the pathway sensitizes tumor cells to cisplatin.
Academic Article	The Ras/Rac1/Cdc42/SEK/JNK/c-Jun cascade is a key pathway by which agonists stimulate DNA synthesis in primary cultures of rat hepatocytes.
Academic Article	The roles of signaling by the p42/p44 mitogen-activated protein (MAP) kinase pathway; a potential route to radio- and chemo-sensitization of tumor cells resulting in the induction of apoptosis and loss of clonogenicity.
Academic Article	Frequent loss of KAI1 expression in squamous and lymphoid neoplasms. An immunohistochemical study of archival tissues.
Academic Article	Expression of human papilloma virus E7 protein causes apoptosis and inhibits DNA synthesis in primary hepatocytes via increased expression of p21(Cip-1/WAF1/MDA6).
Academic Article	Inhibition of the mitogen activated protein kinase pathway potentiates radiation-induced cell killing via cell cycle arrest at the G2/M transition and independently of increased signaling by the JNK/c-Jun pathway.
Academic Article	p27 and cyclin D1 abnormalities in uterine papillary serous carcinoma.
Academic Article	Endocervical cancer is associated with an increase in the ligands and receptors for transforming growth factor-beta and a contrasting decrease in p27(Kip1).
Academic Article	Lovastatin induces apoptosis in a primitive neuroectodermal tumor cell line in association with RB down-regulation and loss of the G1 checkpoint.
Academic Article	Alterations in the gene expression profile of MCF-7 breast tumor cells in response to c-Jun.
Academic Article	c-Jun activation-dependent tumorigenic transformation induced paradoxically by overexpression or block of S-adenosylmethionine decarboxylase.
Academic Article	The role of p27 in endometrial carcinoma.
Academic Article	Simultaneous blockade of AP-1 and phosphatidylinositol 3-kinase pathway in non-small cell lung cancer cells.
Academic Article	FOXO3a loss is a frequent early event in high-grade pelvic serous carcinogenesis.
Academic Article	A SNaPshot of potentially personalized care: Molecular diagnostics in gynecologic cancer.
Academic Article	Phase I dose escalation study of the PI3kinase pathway inhibitor BKM120 and the oral poly (ADP ribose) polymerase (PARP) inhibitor olaparib for the treatment of high-grade serous ovarian and breast cancer.
Grant	A Phase I/IIa, Open-label, Multi-center Study to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of the ATR Kinase Inhibitor ART0380 Administered Orally as Monotherapy...
Grant	A Phase I/IIa, Open-label, Multi-center Study to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of the ATR Kinase Inhibitor ART0380 Administered Orally as Monotherapy...

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Phosphotransferases