 Biological Availability
"Biological Availability" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The extent to which the active ingredient of a drug dosage form becomes available at the site of drug action or in a biological medium believed to reflect accessibility to a site of action.
| Descriptor ID |
D001682
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| MeSH Number(s) |
G03.787.151 G07.690.725.129
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| Concept/Terms |
Biological Availability- Biological Availability
- Availability, Biological
- Availabilities, Biological
- Biological Availabilities
- Biologic Availability
- Physiologic Availability
- Availability, Biologic
- Availabilities, Biologic
- Biologic Availabilities
- Bioavailability
- Bioavailabilities
- Availability, Physiologic
- Availabilities, Physiologic
- Physiologic Availabilities
Availability Equivalency- Availability Equivalency
- Availability Equivalencies
- Equivalencies, Availability
- Equivalency, Availability
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Below are MeSH descriptors whose meaning is more general than "Biological Availability".
Below are MeSH descriptors whose meaning is more specific than "Biological Availability".
This graph shows the total number of publications written about "Biological Availability" by people in UAMS Profiles by year, and whether "Biological Availability" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 2 | 0 | 2 | | 2022 | 0 | 2 | 2 | | 2021 | 0 | 3 | 3 | | 2020 | 1 | 3 | 4 | | 2019 | 0 | 3 | 3 | | 2018 | 0 | 2 | 2 | | 2017 | 0 | 3 | 3 | | 2016 | 0 | 6 | 6 | | 2015 | 0 | 3 | 3 | | 2014 | 0 | 6 | 6 | | 2013 | 0 | 5 | 5 | | 2012 | 0 | 4 | 4 | | 2011 | 0 | 6 | 6 | | 2010 | 0 | 4 | 4 | | 2009 | 0 | 3 | 3 | | 2008 | 0 | 5 | 5 | | 2007 | 0 | 5 | 5 | | 2006 | 0 | 2 | 2 | | 2005 | 0 | 5 | 5 | | 2004 | 0 | 7 | 7 | | 2003 | 0 | 6 | 6 | | 2002 | 0 | 3 | 3 | | 1999 | 0 | 2 | 2 | | 1996 | 0 | 1 | 1 | | 1989 | 0 | 1 | 1 |
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Below are the most recent publications written about "Biological Availability" by people in Profiles over the past ten years.
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Song J, Bao R, Lin M, Li W, Zhao P, Liu X, Fu Q. Investigation of the dissolution rate and oral bioavailability of atenolol-irbesartan co-amorphous systems. Int J Pharm. 2024 Nov 15; 665:124704.
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Hanley MJ, Zhang S, Griffin R, Zhu SX, Fram RJ, Lin J, Venkatakrishnan K, Gupta N. A phase 1 study to assess the absolute bioavailability, mass balance, pharmacokinetics, metabolism, and excretion of [14C]-mobocertinib, an oral inhibitor of EGFR exon 20 insertion mutations, in healthy participants. Invest New Drugs. 2024 Aug; 42(4):343-352.
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Lila MA, Hoskin RT, Grace MH, Xiong J, Strauch R, Ferruzzi M, Iorizzo M, Kay C. Boosting the Bioaccessibility of Dietary Bioactives by Delivery as Protein-Polyphenol Aggregate Particles. J Agric Food Chem. 2022 Oct 19; 70(41):13017-13026.
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Uyoga MA, Mzembe G, Stoffel NU, Moretti D, Zeder C, Phiri K, Sabatier M, Hays NP, Zimmermann MB, Mwangi MN. Iron Bioavailability from Infant Cereals Containing Whole Grains and Pulses: A Stable Isotope Study in Malawian Children. J Nutr. 2022 03 03; 152(3):826-834.
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Kumar A, Chidambaram V, Mehta JL. Plant-Based Diet, Gut?Microbiota, and Bioavailability of Lignans. J Am Coll Cardiol. 2021 12 14; 78(24):e311.
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Hayes M, Corbin S, Nunn C, Pottorff M, Kay CD, Lila MA, Iorrizo M, Ferruzzi MG. Influence of simulated food and oral processing on carotenoid and chlorophyll in vitro bioaccessibility among six spinach genotypes. Food Funct. 2021 Aug 02; 12(15):7001-7016.
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Schleiff MA, Payakachat S, Schleiff BM, Swamidass SJ, Boysen G, Miller GP. Impacts of diphenylamine NSAID halogenation on bioactivation risks. Toxicology. 2021 06 30; 458:152832.
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Kruger J, Taylor JRN, Ferruzzi MG, Debelo H. What is food-to-food fortification? A working definition and framework for evaluation of efficiency and implementation of best practices. Compr Rev Food Sci Food Saf. 2020 11; 19(6):3618-3658.
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Mohamedshah Z, Chadwick-Corbin S, Wightman JD, Ferruzzi MG. Comparative assessment of phenolic bioaccessibility from 100% grape juice and whole grapes. Food Funct. 2020 Jul 01; 11(7):6433-6445.
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Hayes M, Ferruzzi MG. Update on the bioavailability and chemopreventative mechanisms of dietary chlorophyll derivatives. Nutr Res. 2020 09; 81:19-37.
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Ho KKHY, Ferruzzi MG, Wightman JD. Potential health benefits of (poly)phenols derived from fruit and 100% fruit juice. Nutr Rev. 2020 02 01; 78(2):145-174.
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Wolfe RR, Park S, Kim IY, Moughan PJ, Ferrando AA. Advances in stable isotope tracer methodology part 2: new thoughts about an "old" method-measurement of whole body protein synthesis and breakdown in the fed state. J Investig Med. 2020 01; 68(1):11-15.
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Goode GA, Wagh SJ, Irby DJ, Ma D, Jacobs RF, Kearns GL, Almoazen H. Bioavailability testing of a newly developed clindamycin oral suspension in a pediatric porcine model. Pharm Dev Technol. 2019 Oct; 24(8):1038-1043.
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Wolfe RR, Park S, Kim IY, Starck C, Marquis BJ, Ferrando AA, Moughan PJ. Quantifying the contribution of dietary protein to whole body protein kinetics: examination of the intrinsically labeled proteins method. Am J Physiol Endocrinol Metab. 2019 07 01; 317(1):E74-E84.
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Elegbede JL, Li M, Jones OG, Campanella OH, Ferruzzi MG. Interactions Between Flavonoid-Rich Extracts and Sodium Caseinate Modulate Protein Functionality and Flavonoid Bioaccessibility in Model Food Systems. J Food Sci. 2018 May; 83(5):1229-1236.
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Rajpal S, Katikaneni P, Deshotels M, Pardue S, Glawe J, Shen X, Akkus N, Modi K, Bhandari R, Dominic P, Reddy P, Kolluru GK, Kevil CG. Total sulfane sulfur bioavailability reflects ethnic and gender disparities in cardiovascular disease. Redox Biol. 2018 05; 15:480-489.
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Estepp JH, Wiczling P, Moen J, Kang G, Mack JM, Liem R, Panepinto JA, Garg U, Kearns G, Neville KA. Hydroxycarbamide in children with sickle cell anaemia after first-dose vs. chronic therapy: pharmacokinetics and predictive models for drug exposure. Br J Clin Pharmacol. 2018 07; 84(7):1478-1485.
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Chen TY, Ferruzzi MG, Wu QL, Simon JE, Talcott ST, Wang J, Ho L, Todd G, Cooper B, Pasinetti GM, Janle EM. Influence of diabetes on plasma pharmacokinetics and brain bioavailability of grape polyphenols and their phase II metabolites in the Zucker diabetic fatty rat. Mol Nutr Food Res. 2017 10; 61(10).
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Furrer AN, Chegeni M, Ferruzzi MG. Impact of potato processing on nutrients, phytochemicals, and human health. Crit Rev Food Sci Nutr. 2018 Jan 02; 58(1):146-168.
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Redan BW, Buhman KK, Novotny JA, Ferruzzi MG. Altered Transport and Metabolism of Phenolic Compounds in Obesity and Diabetes: Implications for Functional Food Development and Assessment. Adv Nutr. 2016 11; 7(6):1090-1104.
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Lipkie TE, Ferruzzi MG, Weaver CM. Low bioaccessibility of vitamin D2 from yeast-fortified bread compared to crystalline D2 bread and D3 from fluid milks. Food Funct. 2016 Nov 09; 7(11):4589-4596.
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Khan MA, Zafaryab M, Mehdi SH, Ahmad I, Rizvi MM. Characterization and anti-proliferative activity of curcumin loaded chitosan nanoparticles in cervical cancer. Int J Biol Macromol. 2016 Dec; 93(Pt A):242-253.
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Li M, Koecher K, Hansen L, Ferruzzi MG. Phenolic recovery and bioaccessibility from milled and finished whole grain oat products. Food Funct. 2016 Aug 10; 7(8):3370-81.
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Bradley JS, Flanagan SD, Arrieta AC, Jacobs R, Capparelli E, Prokocimer P. Pharmacokinetics, Safety and Tolerability of Single Oral or Intravenous Administration of 200 mg Tedizolid Phosphate in Adolescents. Pediatr Infect Dis J. 2016 06; 35(6):628-33.
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Kachenpukdee N, Santerre CR, Ferruzzi MG, Oonsivilai R. Modified Dietary Fiber from Cassava Pulp and Assessment of Mercury Bioaccessibility and Intestinal Uptake Using an In Vitro Digestion/Caco-2 Model System. J Food Sci. 2016 Jul; 81(7):T1854-63.
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Peyro Saint Paul L, Debruyne D, Bernard D, Mock DM, Defer GL. Pharmacokinetics and pharmacodynamics of MD1003 (high-dose biotin) in the treatment of progressive multiple sclerosis. Expert Opin Drug Metab Toxicol. 2016; 12(3):327-44.
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Jacobi JL, Yang B, Li X, Menze AK, Laurentz SM, Janle EM, Ferruzzi MG, McCabe GP, Chapple C, Kirchmaier AL. Impacts on Sirtuin Function and Bioavailability of the Dietary Bioactive Compound Dihydrocoumarin. PLoS One. 2016; 11(2):e0149207.
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Chen TY, Kritchevsky J, Hargett K, Feller K, Klobusnik R, Song BJ, Cooper B, Jouni Z, Ferruzzi MG, Janle EM. Plasma bioavailability and regional brain distribution of polyphenols from apple/grape seed and bilberry extracts in a young swine model. Mol Nutr Food Res. 2015 Dec; 59(12):2432-47.
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Oh H, Smith-Warner SA, Tamimi RM, Wang M, Xu X, Hankinson SE, Fuhrman BJ, Ziegler RG, Eliassen AH. Dietary Fat and Fiber Intakes Are Not Associated with Patterns of Urinary Estrogen Metabolites in Premenopausal Women. J Nutr. 2015 Sep; 145(9):2109-16.
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Wang D, Ho L, Faith J, Ono K, Janle EM, Lachcik PJ, Cooper BR, Jannasch AH, D'Arcy BR, Williams BA, Ferruzzi MG, Levine S, Zhao W, Dubner L, Pasinetti GM. Role of intestinal microbiota in the generation of polyphenol-derived phenolic acid mediated attenuation of Alzheimer's disease ?-amyloid oligomerization. Mol Nutr Food Res. 2015 Jun; 59(6):1025-40.
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