 Polyphenols
"Polyphenols" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A large class of organic compounds having more than one PHENOL group.
| Descriptor ID |
D059808
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| MeSH Number(s) |
D02.455.426.559.389.657.715 D03.438.150.266.450.260.777
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Polyphenols".
Below are MeSH descriptors whose meaning is more specific than "Polyphenols".
This graph shows the total number of publications written about "Polyphenols" by people in UAMS Profiles by year, and whether "Polyphenols" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 1 | 1 | 2 | | 2023 | 0 | 2 | 2 | | 2022 | 1 | 0 | 1 | | 2021 | 6 | 2 | 8 | | 2020 | 4 | 0 | 4 | | 2019 | 1 | 0 | 1 | | 2018 | 4 | 0 | 4 | | 2017 | 4 | 0 | 4 | | 2016 | 2 | 2 | 4 | | 2015 | 3 | 1 | 4 | | 2014 | 3 | 1 | 4 | | 2013 | 2 | 0 | 2 | | 2012 | 1 | 3 | 4 | | 2011 | 1 | 0 | 1 | | 2010 | 0 | 1 | 1 | | 2009 | 0 | 3 | 3 | | 2008 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Polyphenols" by people in Profiles over the past ten years.
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Lyu W, Yin Z, Xie L, Pasinetti GM, Murrough JW, Marchidan M, Karpman E, Dobbs M, Ferruzzi MG, Simon JE, Wu Q. Method development with high-throughput enhanced matrix removal followed by UHPLC-QqQ-MS/MS for analysis of grape polyphenol metabolites in human urine. J Chromatogr B Analyt Technol Biomed Life Sci. 2024 Jul 15; 1242:124189.
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Ismaeel A, McDermott MM, Joshi JK, Sturgis JC, Zhang D, Ho KJ, Sufit R, Ferrucci L, Peterson CA, Kosmac K. Cocoa flavanols, Nrf2 activation, and oxidative stress in peripheral artery disease: mechanistic findings in muscle based on outcomes from a randomized trial. Am J Physiol Cell Physiol. 2024 02 01; 326(2):C589-C605.
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Meister ML, Feresin RG. Blackberry consumption protects against e-cigarette-induced vascular oxidative stress in mice. Food Funct. 2023 Dec 11; 14(24):10709-10730.
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Najjar RS, Roy RK, Stern JE, Feresin RG. Raspberry polyphenols target molecular pathways of heart failure. J Nutr Biochem. 2024 02; 124:109535.
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Cruz-Carri?n ?, Calani L, de Azua MJR, Mena P, Del Rio D, Su?rez M, Arola-Arnal A. (Poly)phenolic composition of tomatoes from different growing locations and their absorption in rats: A comparative study. Food Chem. 2022 Sep 15; 388:132984.
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Lila MA, Hoskin RT, Grace MH, Xiong J, Strauch R, Ferruzzi M, Iorizzo M, Kay C. Boosting the Bioaccessibility of Dietary Bioactives by Delivery as Protein-Polyphenol Aggregate Particles. J Agric Food Chem. 2022 Oct 19; 70(41):13017-13026.
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Feresin RG, Johnson SA, Elam ML, Pourafshar S, Navaei N, Akhavan NS, Tenenbaum G, Figueroa A, Arjmandi BH. Effects of strawberries on bone biomarkers in pre- and stage 1-hypertensive postmenopausal women: a secondary analysis. Food Funct. 2021 Dec 13; 12(24):12526-12534.
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Cladis DP, Weaver CM, Ferruzzi MG. (Poly)phenol toxicity in vivo following oral administration: A targeted narrative review of (poly)phenols from green tea, grape, and anthocyanin-rich extracts. Phytother Res. 2022 Jan; 36(1):323-335.
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Jameson TSO, Pavis GF, Dirks ML, Lee BP, Abdelrahman DR, Murton AJ, Porter C, Alamdari N, Mikus CR, Wall BT, Stephens FB. Reducing NF-?B Signaling Nutritionally is Associated with Expedited Recovery of Skeletal Muscle Function After Damage. J Clin Endocrinol Metab. 2021 06 16; 106(7):2057-2076.
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Najjar RS, Schwartz AM, Wong BJ, Mehta PK, Feresin RG. Berries and Their Polyphenols as a Potential Therapy for Coronary Microvascular Dysfunction: A Mini-Review. Int J Mol Sci. 2021 Mar 25; 22(7).
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Cladis DP, Simpson AMR, Cooper KJ, Nakatsu CH, Ferruzzi MG, Weaver CM. Blueberry polyphenols alter gut microbiota & phenolic metabolism in rats. Food Funct. 2021 Mar 21; 12(6):2442-2456.
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Najjar RS, Feresin RG. Protective Role of Polyphenols in Heart Failure: Molecular Targets and Cellular Mechanisms Underlying Their Therapeutic Potential. Int J Mol Sci. 2021 Feb 07; 22(4).
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Najjar RS, Turner CG, Wong BJ, Feresin RG. Berry-Derived Polyphenols in Cardiovascular Pathologies: Mechanisms of Disease and the Role of Diet and Sex. Nutrients. 2021 Jan 27; 13(2).
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Land Lail H, Feresin RG, Hicks D, Stone B, Price E, Wanders D. Berries as a Treatment for Obesity-Induced Inflammation: Evidence from Preclinical Models. Nutrients. 2021 Jan 23; 13(2).
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Olson KR, Gao Y, Straub KD. Oxidation of Hydrogen Sulfide by Quinones: How Polyphenols Initiate Their Cytoprotective Effects. Int J Mol Sci. 2021 Jan 19; 22(2).
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Najjar RS, Akhavan NS, Pourafshar S, Arjmandi BH, Feresin RG. Cornus officinalis var. koreana Kitam polyphenol extract decreases pro-inflammatory markers in lipopolysaccharide (LPS)-induced RAW 264.7 macrophages by reducing Akt phosphorylation. J Ethnopharmacol. 2021 Apr 24; 270:113734.
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Cladis DP, Debelo H, Lachcik PJ, Ferruzzi MG, Weaver CM. Increasing Doses of Blueberry Polyphenols Alters Colonic Metabolism and Calcium Absorption in Ovariectomized Rats. Mol Nutr Food Res. 2020 06; 64(12):e2000031.
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Cladis DP, Li S, Reddivari L, Cox A, Ferruzzi MG, Weaver CM. A 90 day oral toxicity study of blueberry polyphenols in ovariectomized sprague-dawley rats. Food Chem Toxicol. 2020 May; 139:111254.
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Ho KKHY, Ferruzzi MG, Wightman JD. Potential health benefits of (poly)phenols derived from fruit and 100% fruit juice. Nutr Rev. 2020 02 01; 78(2):145-174.
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Arola-Arnal A, Cruz-Carri?n ?, Torres-Fuentes C, ?vila-Rom?n J, Aragon?s G, Mulero M, Bravo FI, Muguerza B, Arola L, Su?rez M. Chrononutrition and Polyphenols: Roles and Diseases. Nutrients. 2019 Oct 30; 11(11).
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Lavoie S, Sweeney-Jones AM, Mojib N, Dale B, Gagaring K, McNamara CW, Quave CL, Soapi K, Kubanek J. Antibacterial Oligomeric Polyphenols from the Green Alga Cladophora socialis. J Org Chem. 2019 05 03; 84(9):5035-5045.
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Jajtner AR, Townsend JR, Beyer KS, Varanoske AN, Church DD, Oliveira LP, Herrlinger KA, Radom-Aizik S, Fukuda DH, Stout JR, Hoffman JR. Resistance Exercise Selectively Mobilizes Monocyte Subsets: Role of Polyphenols. Med Sci Sports Exerc. 2018 11; 50(11):2231-2241.
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Moser S, Aragon I, Furrer A, Van Klinken JW, Kaczmarczyk M, Lee BH, George J, Hamaker BR, Mattes R, Ferruzzi MG. Potato phenolics impact starch digestion and glucose transport in model systems but translation to phenolic rich potato chips results in only modest modification of glycemic response in humans. Nutr Res. 2018 04; 52:57-70.
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Ho L, Cheng H, Wang J, Simon JE, Wu Q, Zhao D, Carry E, Ferruzzi MG, Faith J, Valcarcel B, Hao K, Pasinetti GM. A Comprehensive Database and Analysis Framework To Incorporate Multiscale Data Types and Enable Integrated Analysis of Bioactive Polyphenols. Mol Pharm. 2018 03 05; 15(3):840-850.
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Townsend JR, Stout JR, Jajtner AR, Church DD, Beyer KS, Riffe JJ, Muddle TWD, Herrlinger KL, Fukuda DH, Hoffman JR. Polyphenol supplementation alters intramuscular apoptotic signaling following acute resistance exercise. Physiol Rep. 2018 01; 6(2).
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Beyer KS, Stout JR, Fukuda DH, Jajtner AR, Townsend JR, Church DD, Wang R, Riffe JJ, Muddle TWD, Herrlinger KA, Hoffman JR. Impact of Polyphenol Supplementation on Acute and Chronic Response to Resistance Training. J Strength Cond Res. 2017 Nov; 31(11):2945-2954.
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Novotny JA, Chen TY, Terekhov AI, Gebauer SK, Baer DJ, Ho L, Pasinetti GM, Ferruzzi MG. The effect of obesity and repeated exposure on pharmacokinetic response to grape polyphenols in humans. Mol Nutr Food Res. 2017 11; 61(11).
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Chen TY, Ferruzzi MG, Wu QL, Simon JE, Talcott ST, Wang J, Ho L, Todd G, Cooper B, Pasinetti GM, Janle EM. Influence of diabetes on plasma pharmacokinetics and brain bioavailability of grape polyphenols and their phase II metabolites in the Zucker diabetic fatty rat. Mol Nutr Food Res. 2017 10; 61(10).
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Feresin RG, Pourafshar S, Huang J, Zhao Y, Arjmandi BH, Salazar G. Extraction and Purification of Polyphenols from Freeze-dried Berry Powder for the Treatment of Vascular Smooth Muscle Cells In Vitro. J Vis Exp. 2017 07 05; (125).
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Koyama M, Shirahata T, Hirashima R, Kobayashi Y, Itoh T, Fujiwara R. Inhibition of UDP-glucuronosyltransferase (UGT)-mediated glycyrrhetinic acid 3-O-glucuronidation by polyphenols and triterpenoids. Drug Metab Pharmacokinet. 2017 Aug; 32(4):218-223.
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Alimohammadi M, Lahiani MH, McGehee D, Khodakovskaya M. Polyphenolic extract of InsP 5-ptase expressing tomato plants reduce the proliferation of MCF-7 breast cancer cells. PLoS One. 2017; 12(4):e0175778.
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Jajtner AR, Hoffman JR, Townsend JR, Beyer KS, Varanoske AN, Church DD, Oliveira LP, Herrlinger KA, Radom-Aizik S, Fukuda DH, Stout JR. The effect of polyphenols on cytokine and granulocyte response to resistance exercise. Physiol Rep. 2016 12; 4(24).
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Feresin RG, Huang J, Klarich DS, Zhao Y, Pourafshar S, Arjmandi BH, Salazar G. Blackberry, raspberry and black raspberry polyphenol extracts attenuate angiotensin II-induced senescence in vascular smooth muscle cells. Food Funct. 2016 Oct 12; 7(10):4175-4187.
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Dzakovich MP, Ferruzzi MG, Mitchell CA. Manipulating Sensory and Phytochemical Profiles of Greenhouse Tomatoes Using Environmentally Relevant Doses of Ultraviolet Radiation. J Agric Food Chem. 2016 Sep 14; 64(36):6801-8.
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Moser S, Lim J, Chegeni M, Wightman JD, Hamaker BR, Ferruzzi MG. Concord and Niagara Grape Juice and Their Phenolics Modify Intestinal Glucose Transport in a Coupled in Vitro Digestion/Caco-2 Human Intestinal Model. Nutrients. 2016 Jul 05; 8(7).
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Koga CC, Andrade JE, Ferruzzi MG, Lee Y. Stability of Trans-Resveratrol Encapsulated in a Protein Matrix Produced Using Spray Drying to UV Light Stress and Simulated Gastro-Intestinal Digestion. J Food Sci. 2016 Feb; 81(2):C292-300.
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Chen TY, Kritchevsky J, Hargett K, Feller K, Klobusnik R, Song BJ, Cooper B, Jouni Z, Ferruzzi MG, Janle EM. Plasma bioavailability and regional brain distribution of polyphenols from apple/grape seed and bilberry extracts in a young swine model. Mol Nutr Food Res. 2015 Dec; 59(12):2432-47.
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Zhao W, Wang J, Bi W, Ferruzzi M, Yemul S, Freire D, Mazzola P, Ho L, Dubner L, Pasinetti GM. Novel application of brain-targeting polyphenol compounds in sleep deprivation-induced cognitive dysfunction. Neurochem Int. 2015 Oct; 89:191-7.
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Wang D, Ho L, Faith J, Ono K, Janle EM, Lachcik PJ, Cooper BR, Jannasch AH, D'Arcy BR, Williams BA, Ferruzzi MG, Levine S, Zhao W, Dubner L, Pasinetti GM. Role of intestinal microbiota in the generation of polyphenol-derived phenolic acid mediated attenuation of Alzheimer's disease ?-amyloid oligomerization. Mol Nutr Food Res. 2015 Jun; 59(6):1025-40.
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Sinha S, Shukla S, Khan S, Tollefsbol TO, Meeran SM. Epigenetic reactivation of p21CIP1/WAF1 and KLOTHO by a combination of bioactive dietary supplements is partially ERa-dependent in ERa-negative human breast cancer cells. Mol Cell Endocrinol. 2015 May 05; 406:102-14.
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Zhou H, Chen JX, Yang CS, Yang MQ, Deng Y, Wang H. Gene regulation mediated by microRNAs in response to green tea polyphenol EGCG in mouse lung cancer. BMC Genomics. 2014; 15 Suppl 11:S3.
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Church RJ, Gatti DM, Urban TJ, Long N, Yang X, Shi Q, Eaddy JS, Mosedale M, Ballard S, Churchill GA, Navarro V, Watkins PB, Threadgill DW, Harrill AH. Sensitivity to hepatotoxicity due to epigallocatechin gallate is affected by genetic background in diversity outbred mice. Food Chem Toxicol. 2015 Feb; 76:19-26.
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