Area Under Curve
"Area Under Curve" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A statistical means of summarizing information from a series of measurements on one individual. It is frequently used in clinical pharmacology where the AUC from serum levels can be interpreted as the total uptake of whatever has been administered. As a plot of the concentration of a drug against time, after a single dose of medicine, producing a standard shape curve, it is a means of comparing the bioavailability of the same drug made by different companies. (From Winslade, Dictionary of Clinical Research, 1992)
Descriptor ID |
D019540
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MeSH Number(s) |
E05.318.740.200 G03.787.101 G07.690.725.064 N06.850.520.830.200
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Concept/Terms |
Area Under Curve- Area Under Curve
- Area Under Curves
- Curve, Area Under
- Curves, Area Under
- Under Curve, Area
- Under Curves, Area
- AUC
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Below are MeSH descriptors whose meaning is more general than "Area Under Curve".
Below are MeSH descriptors whose meaning is more specific than "Area Under Curve".
This graph shows the total number of publications written about "Area Under Curve" by people in UAMS Profiles by year, and whether "Area Under Curve" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2022 | 0 | 1 | 1 | 2021 | 0 | 1 | 1 | 2020 | 0 | 3 | 3 | 2019 | 0 | 2 | 2 | 2018 | 0 | 4 | 4 | 2017 | 0 | 5 | 5 | 2016 | 0 | 3 | 3 | 2015 | 0 | 4 | 4 | 2014 | 0 | 6 | 6 | 2013 | 0 | 3 | 3 | 2012 | 0 | 1 | 1 | 2011 | 0 | 4 | 4 | 2009 | 0 | 4 | 4 | 2008 | 0 | 5 | 5 | 2007 | 0 | 3 | 3 | 2006 | 0 | 3 | 3 | 2005 | 0 | 7 | 7 | 2004 | 0 | 8 | 8 | 2003 | 0 | 11 | 11 | 2001 | 0 | 1 | 1 | 1998 | 0 | 3 | 3 | 1997 | 0 | 1 | 1 |
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Below are the most recent publications written about "Area Under Curve" by people in Profiles over the past ten years.
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Erriquez A, Uretsky BF, Brugaletta S, Spitaleri G, Cerrato E, Quadri G, Manfrini M, Pompei G, Scancarello D, Trichilo M, Marchini F, Caglioni S, Campana R, Marrone A, Penzo C, Tumscitz C, Tebaldi M, Verardi FM, Scala A, Campo G, Biscaglia S. Impact of trans-stent gradient on outcome after PCI: results from a HAWKEYE substudy. Int J Cardiovasc Imaging. 2022 Dec; 38(12):2819-2827.
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Rybak MJ, Le J, Lodise TP, Levine DP, Bradley JS, Liu C, Mueller BA, Pai MP, Wong-Beringer A, Rodvold KA, Maples HD. Questions on Vancomycin Dosing. Clin Infect Dis. 2021 10 05; 73(7):e1777-e1778.
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Schmitz ML, Rubino CM, Onufrak NJ, Martinez DV, Licursi D, Karpf A, Cetnarowski W. Pharmacokinetics and Optimal Dose Selection of Cefazolin for Surgical Prophylaxis of Pediatric Patients. J Clin Pharmacol. 2021 05; 61(5):666-676.
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Sosenko JM, Skyler JS, Herold KC, Schatz DA, Haller MJ, Pugliese A, Cleves M, Geyer S, Rafkin LE, Matheson D, Palmer JP. Slowed Metabolic Decline After 1 Year of Oral Insulin Treatment Among Individuals at High Risk for Type 1 Diabetes in the Diabetes Prevention Trial-Type 1 (DPT-1) and TrialNet Oral Insulin Prevention Trials. Diabetes. 2020 08; 69(8):1827-1832.
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Soong D, Stratford J, Avet-Loiseau H, Bahlis N, Davies F, Dispenzieri A, Sasser AK, Schecter JM, Qi M, Brown C, Jones W, Keats JJ, Auclair D, Chiu C, Powers J, Schaffer M. CNV Radar: an improved method for somatic copy number alteration characterization in oncology. BMC Bioinformatics. 2020 Mar 06; 21(1):98.
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Goode GA, Wagh SJ, Irby DJ, Ma D, Jacobs RF, Kearns GL, Almoazen H. Bioavailability testing of a newly developed clindamycin oral suspension in a pediatric porcine model. Pharm Dev Technol. 2019 Oct; 24(8):1038-1043.
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Ormseth MJ, Solus JF, Sheng Q, Ye F, Wu Q, Guo Y, Oeser AM, Allen RM, Vickers KC, Stein CM. Development and Validation of a MicroRNA Panel to Differentiate Between Patients with Rheumatoid Arthritis or Systemic Lupus Erythematosus and Controls. J Rheumatol. 2020 02; 47(2):188-196.
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Li D, Yang W, Zhang Y, Yang JY, Guan R, Xu D, Yang MQ. Genomic analyses based on pulmonary adenocarcinoma in situ reveal early lung cancer signature. BMC Med Genomics. 2018 Nov 20; 11(Suppl 5):106.
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Shakhnovich V, Brian Smith P, Guptill JT, James LP, Collier DN, Wu H, Livingston CE, Zhao J, Kearns GL, Cohen-Wolkowiez M. A Population-Based Pharmacokinetic Model Approach to Pantoprazole Dosing for Obese Children and Adolescents. Paediatr Drugs. 2018 Oct; 20(5):483-495.
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Peloquin CA, Phillips PPJ, Mitnick CD, Eisenach K, Patientia RF, Lecca L, Gotuzzo E, Gandhi NR, Butler D, Diacon AH, Martel B, Santillan J, Hunt KR, Vargas D, von Groote-Bidlingmaier F, Seas C, Dianis N, Moreno-Martinez A, Kaur P, Horsburgh CR. Increased Doses Lead to Higher Drug Exposures of Levofloxacin for Treatment of Tuberculosis. Antimicrob Agents Chemother. 2018 10; 62(10).
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Patel YA, Gifford EJ, Glass LM, Turner MJ, Han B, Moylan CA, Choi S, Suzuki A, Provenzale D, Hunt CM. Identifying Nonalcoholic Fatty Liver Disease Advanced Fibrosis in the Veterans Health Administration. Dig Dis Sci. 2018 09; 63(9):2259-2266.
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Estepp JH, Wiczling P, Moen J, Kang G, Mack JM, Liem R, Panepinto JA, Garg U, Kearns G, Neville KA. Hydroxycarbamide in children with sickle cell anaemia after first-dose vs. chronic therapy: pharmacokinetics and predictive models for drug exposure. Br J Clin Pharmacol. 2018 07; 84(7):1478-1485.
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Novotny JA, Chen TY, Terekhov AI, Gebauer SK, Baer DJ, Ho L, Pasinetti GM, Ferruzzi MG. The effect of obesity and repeated exposure on pharmacokinetic response to grape polyphenols in humans. Mol Nutr Food Res. 2017 11; 61(11).
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Gonzalez D, Bradley JS, Blumer J, Yogev R, Watt KM, James LP, Palazzi DL, Bhatt-Mehta V, Sullivan JE, Zhang L, Murphy J, Ussery XT, Puttagunta S, Dunne MW, Cohen-Wolkowiez M. Dalbavancin Pharmacokinetics and Safety in Children 3 Months to 11 Years of Age. Pediatr Infect Dis J. 2017 07; 36(7):645-653.
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Thandassery RB, Kaabi SA, Soofi ME, Tharian B, Singh R. Noninvasive serum models to predict significant liver related events in chronic hepatitis C. Hepatol Int. 2017 Jul; 11(4):401-408.
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Dang NL, Hughes TB, Miller GP, Swamidass SJ. Computational Approach to Structural Alerts: Furans, Phenols, Nitroaromatics, and Thiophenes. Chem Res Toxicol. 2017 04 17; 30(4):1046-1059.
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Tolbert JA, Bai S, Abdel-Rahman SM, August KJ, Weir SJ, Kearns GL, Neville KA. Pharmacokinetics of two 6-mercaptopurine liquid formulations in children with acute lymphoblastic leukemia. Pediatr Blood Cancer. 2017 Aug; 64(8).
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Owens SM, Pollard GT, Howard JL, Fennell TR, Snyder RW, Carroll FI. Pharmacodynamic Relationships between Duration of Action of JDTic-like Kappa-Opioid Receptor Antagonists and Their Brain and Plasma Pharmacokinetics in Rats. ACS Chem Neurosci. 2016 12 21; 7(12):1737-1745.
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Kim JE, Ferruzzi MG, Campbell WW. Egg Consumption Increases Vitamin E Absorption from Co-Consumed Raw Mixed Vegetables in Healthy Young Men. J Nutr. 2016 Nov; 146(11):2199-2205.
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Kasula S, Agarwal SK, Hacioglu Y, Pothineni NK, Bhatti S, Ahmed Z, Uretsky B, Hakeem A. Clinical and prognostic value of poststenting fractional flow reserve in acute coronary syndromes. Heart. 2016 12 15; 102(24):1988-1994.
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Al Fayyadh MJ, Heller SF, Rajab TK, Gardner AK, Bloom JP, Rawlings JA, Mullen JT, Smink DS, Farley DR, Willis RE, Dent DL. Predicting Success of Preliminary Surgical Residents: A Multi-Institutional Study. J Surg Educ. 2016 Nov - Dec; 73(6):e77-e83.
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Kearns GL, Chumpitazi BP, Abdel-Rahman SM, Garg U, Shulman RJ. Systemic exposure to menthol following administration of peppermint oil to paediatric patients. BMJ Open. 2015 Aug 12; 5(8):e008375.
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