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Jin-Ran Chen

TitleAssociate Professor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentPeds Pediatrics, College of Medicine
DivisionPeds Developmental Nutrition
Address ACH Sturgis Building
1212 Marshall Street
Mail Slot # 512-20B
Little Rock AR 72202
Phone501-364-2707
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    Collapse Research 
    Collapse research activities and funding
    ACRI # 039141     (CHEN, JIN-RAN)Dec 1, 2017 - Nov 30, 2018
    UAMS ACHRI Flow Through
    Dietary Soy Proteins During Early Life Program Bone Formation
    Role: Principal Investigator
    ACRI#039141     (CHEN, JIN-RAN)Dec 1, 2017 - Nov 30, 2018
    UAMS ACHRI Flow Through
    Dietary Soy Proteins During Early Life Program Bone Formation
    Role: Principal Investigator
    ACRI # 034960     (CHEN, JIN-RAN)May 15, 2016 - Apr 30, 2021
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI # 034961     (CHEN, JIN-RAN)May 15, 2016 - Apr 30, 2021
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI # TBD     (CHEN, JIN-RAN)May 15, 2016 - Apr 30, 2021
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI#034960     (CHEN, JIN-RAN)May 15, 2016 - Apr 30, 2021
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI#034961     (CHEN, JIN-RAN)May 15, 2016 - Apr 30, 2021
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI#TBD     (CHEN, JIN-RAN)May 15, 2016 - Apr 30, 2021
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    TBD     (CHEN, JIN-RAN)May 15, 2016 - Apr 30, 2021
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACHRI #036164     (CHEN, JIN-RAN)Nov 19, 2014 - Nov 30, 2015
    UAMS College of Medicine
    CUMG
    Role: Principal Investigator
    ACHRI#036164     (CHEN, JIN-RAN)Nov 19, 2014 - Nov 30, 2015
    UAMS College of Medicine
    CUMG
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Chen JR, Samuel HA, Shlisky J, Sims CR, Lazarenko OP, Williams DK, Andres A, Badger TM. A longitudinal observational study of skeletal development between ages 3 mo and 6 y in children fed human milk, milk formula, or soy formula. Am J Clin Nutr. 2023 06; 117(6):1211-1218. PMID: 37028556.
      View in: PubMed
    2. Chen JR, Lazarenko OP, Blackburn ML, Chen JF, Randolph CE, Zabaleta J, Schroder K, Pedersen KB, Ronis MJJ. Nox4 expression in osteo-progenitors controls bone development in mice during early life. Commun Biol. 2022 06 14; 5(1):583. PMID: 35701603.
      View in: PubMed
    3. Chen JR, Lazarenko OP, Blackburn ML. GPR109A gene deletion ameliorates gonadectomy-induced bone loss in mice. Bone. 2022 08; 161:116422. PMID: 35489706.
      View in: PubMed
    4. Chen JR, Zhao H, Wankhade UD, Chintapalli SV, Li C, Gai D, Shankar K, Zhan F, Lazarenko OP. GPR109A mediates the effects of hippuric acid on regulating osteoclastogenesis and bone resorption in mice. Commun Biol. 2021 01 08; 4(1):53. PMID: 33420329.
      View in: PubMed
    5. Chen JR, Lazarenko OP, Blackburn ML, Shankar K. Dietary factors during early life program bone formation in female rats. FASEB J. 2017 01; 31(1):376-387. PMID: 27733448.
      View in: PubMed
    6. Chen JR, Lazarenko OP, Blackburn ML, Mercer KE, Badger TM, Ronis MJ. p47phox-Nox2-dependent ROS Signaling Inhibits Early Bone Development in Mice but Protects against Skeletal Aging. J Biol Chem. 2015 Jun 05; 290(23):14692-704. PMID: 25922068.
      View in: PubMed
    7. Chen JR, Zhang J, Lazarenko OP, Cao JJ, Blackburn ML, Badger TM, Ronis MJ. Soy protein isolates prevent loss of bone quantity associated with obesity in rats through regulation of insulin signaling in osteoblasts. FASEB J. 2013 Sep; 27(9):3514-23. PMID: 23776073.
      View in: PubMed
    8. Ronis M, Mercer K, Suva L, Badger TM, J Chen. Role of nadph oxidases and reactive oxygen species in regulation of bone turnover and the skeletal toxicity of alcohol. 52nd Annual Meeting & ToxExpo. 2013.
    9. Zhang J, Lazarenko O, Badger T, Ronis M, J Chen. Persistent effects of a soy diet in early development on bone in female rats. EB2013. 2013.
    10. Mercer K, Wynne R, Lazarenko O, Lumpkin C, Hogue W, Suva L, J Chen, Badger T, Ronis M. Vitamin D supplementation prevents hypocalcaemia and cortical bone loss associated with chronic alcohol feeding in female mice. ASBMR 2012 Annual Meeting. 2012.
    11. Mercer K, Suva L, Badger T, J Chen, Ronis M. Ros/Redux signaling regulates bone turnover in an age-specific manner in female mice. ASBMR Annual Meeting 2012. 2012.
    12. Chen J, Mercer K, Lazarenko OP, Badger TM, Ronis MJJ. Impairment of osteoclastic bone resorption in rapidly growing female p47 phox knockout mice. ASBMR 2012 Annual Meeting. 2012.
    13. Chen J, Zhang J, Lazarenko OP, Cao JJ, Badger TM, Ronis MJJ. Skeletal effects of obesity are prevented by a diet containing soy protein isolate via preservation of insulin signaling in bone. ASBMR 2012 Annual Meeting. 2012.
    14. Chen JR, Zhang J, Lazarenko OP, Kang P, Blackburn ML, Ronis MJ, Badger TM, Shankar K. Inhibition of fetal bone development through epigenetic down-regulation of HoxA10 in obese rats fed high-fat diet. FASEB J. 2012 Mar; 26(3):1131-41. PMID: 22131269.
      View in: PubMed
    15. Chen JR, Lazarenko OP, Wu X, Kang J, Blackburn ML, Shankar K, Badger TM, Ronis MJ. Dietary-induced serum phenolic acids promote bone growth via p38 MAPK/beta-catenin canonical Wnt signaling. J Bone Miner Res. 2010; 25(11):2399 - 2411.
    16. Chen JR, Lazarenko OP, Wu X, Kang J, Blackburn ML, Shankar K, Badger TM, Ronis MJ. Dietary-induced serum phenolic acids promote bone growth via p38 MAPK/?-catenin canonical Wnt signaling. J Bone Miner Res. 2010 Nov; 25(11):2399-411. PMID: 20499363.
      View in: PubMed
    17. Chen JR, Lazarenko OP, Wu X, Tong Y, Blackburn ML, Shankar K, Badger TM, Ronis MJ. Obesity reduces bone density associated with activation of PPAR? and suppression of Wnt/?-catenin in rapidly growing male rats. PLoS One. 2010 Oct 28; 5(10):e13704. PMID: 21060836.
      View in: PubMed
    18. Chen JR, Lazarenko OP, Shankar K, Blackburn ML, Badger TM, Ronis MJ. A role for ethanol-induced oxidative stress in controlling lineage commitment of mesenchymal stromal cells through inhibition of Wnt/beta-catenin signaling. J Bone Miner Res. 2010 May; 25(5):1117-27. PMID: 20200986.
      View in: PubMed
    19. Chen JR, Lazarenko OP, Wu X, Tong Y, Blackburn ML, Shankar K, Badger TM, Ronis MJ. Obesity reduces bone density associated with activation of PPARgamma and suppression of Wnt/beta-catenin in rapidly growing male rats. PLoS One. 2010; 5(10):e13704 - .
    20. Chen JR, Lazarenko OP, Blackburn ML, Badeaux JV, Badger TM, Ronis MJ. Infant formula promotes bone growth in neonatal piglets by enhancing osteoblastogenesis through bone morphogenic protein signaling. J Nutr. 2009 Oct; 139(10):1839-47. PMID: 19710159.
      View in: PubMed
    21. Chen JR, Lazarenko OP, Haley RL, Blackburn ML, Badger TM, Ronis MJ. Ethanol impairs estrogen receptor signaling resulting in accelerated activation of senescence pathways, whereas estradiol attenuates the effects of ethanol in osteoblasts. J Bone Miner Res. 2009 Feb; 24(2):221-30. PMID: 18847333.
      View in: PubMed
    22. Chen JR, Singhal R, Lazarenko OP, Liu X, Hogue WR, Badger TM, Ronis MJ. Short term effects on bone quality associated with consumption of soy protein isolate and other dietary protein sources in rapidly growing female rats. Exp Biol Med (Maywood). 2008 Nov; 233(11):1348-58. PMID: 18703746.
      View in: PubMed
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