 Estrogen Receptor alpha
"Estrogen Receptor alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the ESTROGEN RECEPTORS that has marked affinity for ESTRADIOL. Its expression and function differs from, and in some ways opposes, ESTROGEN RECEPTOR BETA.
| Descriptor ID |
D047628
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| MeSH Number(s) |
D12.776.260.698.750.350.174 D12.776.826.750.350.174 D12.776.930.669.750.350.174
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| Concept/Terms |
Estrogen Receptor alpha- Estrogen Receptor alpha
- Estrogen Receptors alpha
- Estradiol Receptor alpha
- Receptor alpha, Estradiol
- alpha, Estradiol Receptor
- ERalpha
- Receptor alpha, Estrogen
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Below are MeSH descriptors whose meaning is more general than "Estrogen Receptor alpha".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- DNA-Binding Proteins [D12.776.260]
- Receptors, Cytoplasmic and Nuclear [D12.776.260.698]
- Receptors, Steroid [D12.776.260.698.750]
- Receptors, Estrogen [D12.776.260.698.750.350]
- Estrogen Receptor alpha [D12.776.260.698.750.350.174]
- Receptors, Cytoplasmic and Nuclear [D12.776.826]
- Receptors, Steroid [D12.776.826.750]
- Receptors, Estrogen [D12.776.826.750.350]
- Estrogen Receptor alpha [D12.776.826.750.350.174]
- Transcription Factors [D12.776.930]
- Receptors, Cytoplasmic and Nuclear [D12.776.930.669]
- Receptors, Steroid [D12.776.930.669.750]
- Receptors, Estrogen [D12.776.930.669.750.350]
- Estrogen Receptor alpha [D12.776.930.669.750.350.174]
Below are MeSH descriptors whose meaning is more specific than "Estrogen Receptor alpha".
This graph shows the total number of publications written about "Estrogen Receptor alpha" by people in UAMS Profiles by year, and whether "Estrogen Receptor alpha" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 0 | 1 | 1 | | 2022 | 0 | 2 | 2 | | 2020 | 0 | 1 | 1 | | 2019 | 1 | 2 | 3 | | 2018 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 | | 2016 | 0 | 2 | 2 | | 2015 | 3 | 1 | 4 | | 2014 | 1 | 1 | 2 | | 2013 | 2 | 1 | 3 | | 2012 | 3 | 0 | 3 | | 2010 | 5 | 0 | 5 | | 2009 | 1 | 1 | 2 | | 2008 | 0 | 2 | 2 | | 2007 | 1 | 1 | 2 | | 2006 | 0 | 1 | 1 | | 2005 | 1 | 0 | 1 | | 2001 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Estrogen Receptor alpha" by people in Profiles over the past ten years.
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Huang T, Lu Z, Wang Z, Cheng L, Gao L, Gao J, Zhang N, Geng CA, Zhao X, Wang H, Wong CW, Yeung KWK, Pan H, Lu WW, Guan M. Targeting adipocyte ESRRA promotes osteogenesis and vascular formation in adipocyte-rich bone marrow. Nat Commun. 2024 May 04; 15(1):3769.
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Xu X, Yang H, Bullock WA, Gallant MA, Ohlsson C, Bellido TM, Main RP. Osteocyte Estrogen Receptor ? (Ot-ER?) Regulates Bone Turnover and Skeletal Adaptive Response to Mechanical Loading Differently in Male and Female Growing and Adult Mice. J Bone Miner Res. 2023 01; 38(1):186-197.
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Altwegg KA, Viswanadhapalli S, Mann M, Chakravarty D, Krishnan S, Liu Z, Liu J, Pratap UP, Ebrahimi B, Sanchez JR, Li X, Ma S, Park BH, Santhamma B, Chen Y, Lai Z, Raj GV, Yuan Y, Zhou D, Sareddy GR, Tekmal RR, McHardy S, Huang TH, Rao MK, Vankayalapati H, Vadlamudi RK. A First-in-Class Inhibitor of ER Coregulator PELP1 Targets ER+ Breast Cancer. Cancer Res. 2022 10 17; 82(20):3830-3844.
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Pabona JMP, Burnett AF, Brown DM, Quick CM, Simmen FA, Montales MTE, Liu SJ, Rose T, Alhallak I, Siegel ER, Simmen RC. Metformin Promotes Anti-tumor Biomarkers in Human Endometrial Cancer Cells. Reprod Sci. 2020 01; 27(1):267-277.
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Win S, Min RW, Chen CQ, Zhang J, Chen Y, Li M, Suzuki A, Abdelmalek MF, Wang Y, Aghajan M, Aung FW, Diehl AM, Davis RJ, Than TA, Kaplowitz N. Expression of mitochondrial membrane-linked SAB determines severity of sex-dependent acute liver injury. J Clin Invest. 2019 12 02; 129(12):5278-5293.
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Dworatzek E, Mahmoodzadeh S, Schriever C, Kusumoto K, Kramer L, Santos G, Fliegner D, Leung YK, Ho SM, Zimmermann WH, Lutz S, Regitz-Zagrosek V. Sex-specific regulation of collagen I and III expression by 17?-Estradiol in cardiac fibroblasts: role of estrogen receptors. Cardiovasc Res. 2019 02 01; 115(2):315-327.
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Miah S, Bagu E, Goel R, Ogunbolude Y, Dai C, Ward A, Vizeacoumar FS, Davies G, Vizeacoumar FJ, Anderson D, Lukong KE. Estrogen receptor signaling regulates the expression of the breast tumor kinase in breast cancer cells. BMC Cancer. 2019 Jan 16; 19(1):78.
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Hou F, Dai Y, Fan CY, Suen JY, Richter GT. Estrogen is involved in hemangioma regression associated with mast cells. Orphanet J Rare Dis. 2018 10 19; 13(1):181.
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Hill BJF, Dalton RJ, Joseph BK, Thakali KM, Rusch NJ. 17?-estradiol reduces Cav 1.2 channel abundance and attenuates Ca2+ -dependent contractions in coronary arteries. Pharmacol Res Perspect. 2017 10; 5(5).
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Ucer S, Iyer S, Kim HN, Han L, Rutlen C, Allison K, Thostenson JD, de Cabo R, Jilka RL, O'Brien C, Almeida M, Manolagas SC. The Effects of Aging and Sex Steroid Deficiency on the Murine Skeleton Are Independent and Mechanistically Distinct. J Bone Miner Res. 2017 Mar; 32(3):560-574.
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Simmen RC, Kelley AS. Reversal of fortune: estrogen receptor-? in endometriosis. J Mol Endocrinol. 2016 08; 57(2):F23-7.
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Ronis MJ, Gomez-Acevedo H, Blackburn ML, Cleves MA, Singhal R, Badger TM. Uterine responses to feeding soy protein isolate and treatment with 17?-estradiol differ in ovariectomized female rats. Toxicol Appl Pharmacol. 2016 Apr 15; 297:68-80.
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Panchanathan R, Liu H, Leung YK, Ho SM, Choubey D. Bisphenol A (BPA) stimulates the interferon signaling and activates the inflammasome activity in myeloid cells. Mol Cell Endocrinol. 2015 Nov 05; 415:45-55.
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Ucer S, Iyer S, Bartell SM, Martin-Millan M, Han L, Kim HN, Weinstein RS, Jilka RL, O'Brien CA, Almeida M, Manolagas SC. The Effects of Androgens on Murine Cortical Bone Do Not Require AR or ERa Signaling in Osteoblasts and Osteoclasts. J Bone Miner Res. 2015 Jul; 30(7):1138-49.
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Yao-Borengasser A, Monzavi-Karbassi B, Hedges RA, Rogers LJ, Kadlubar SA, Kieber-Emmons T. Adipocyte hypoxia promotes epithelial-mesenchymal transition-related gene expression and estrogen receptor-negative phenotype in breast cancer cells. Oncol Rep. 2015 Jun; 33(6):2689-94.
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Sinha S, Shukla S, Khan S, Tollefsbol TO, Meeran SM. Epigenetic reactivation of p21CIP1/WAF1 and KLOTHO by a combination of bioactive dietary supplements is partially ERa-dependent in ERa-negative human breast cancer cells. Mol Cell Endocrinol. 2015 May 05; 406:102-14.
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Wang X, Guo Z, Ding Z, Khaidakov M, Lin J, Xu Z, Sharma SG, Jiwani S, Mehta JL. Endothelin-1 upregulation mediates aging-related cardiac fibrosis. J Mol Cell Cardiol. 2015 Mar; 80:101-9.
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