 Mutagenesis
"Mutagenesis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Process of generating a genetic MUTATION. It may occur spontaneously or be induced by MUTAGENS.
| Descriptor ID |
D016296
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| MeSH Number(s) |
G05.355.600
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Mutagenesis".
Below are MeSH descriptors whose meaning is more specific than "Mutagenesis".
This graph shows the total number of publications written about "Mutagenesis" by people in UAMS Profiles by year, and whether "Mutagenesis" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 0 | 1 | 1 | | 2021 | 3 | 0 | 3 | | 2020 | 2 | 2 | 4 | | 2019 | 0 | 2 | 2 | | 2018 | 2 | 2 | 4 | | 2017 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 | | 2015 | 1 | 1 | 2 | | 2014 | 1 | 1 | 2 | | 2013 | 0 | 2 | 2 | | 2012 | 1 | 0 | 1 | | 2010 | 0 | 2 | 2 | | 2009 | 1 | 1 | 2 | | 2008 | 2 | 4 | 6 | | 2007 | 1 | 1 | 2 | | 2006 | 1 | 2 | 3 | | 2005 | 0 | 1 | 1 | | 2004 | 0 | 4 | 4 | | 2003 | 0 | 3 | 3 | | 2002 | 0 | 2 | 2 | | 2000 | 0 | 2 | 2 | | 1999 | 0 | 1 | 1 | | 1998 | 0 | 2 | 2 | | 1997 | 0 | 1 | 1 | | 1995 | 0 | 1 | 1 | | 1994 | 1 | 0 | 1 | | 1993 | 0 | 2 | 2 | | 1990 | 0 | 1 | 1 |
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Below are the most recent publications written about "Mutagenesis" by people in Profiles over the past ten years.
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Dobrovolsky VN, Atiq OT, Heflich RH, Maisha M, McKinzie PB, Pearce MG, Robison TW. Erythrocyte PIG-A mutant frequencies in cancer patients receiving cisplatin. Cancer Med. 2024 Feb; 13(3):e6895.
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Wang Y, Mittelstaedt RA, Wynne R, Chen Y, Cao X, Muskhelishvili L, Davis K, Robison TW, Sun W, Schmidt EK, Smith TH, Norgaard ZK, Valentine CC, Yaplee J, Williams LN, Salk JJ, Heflich RH. Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing DNA damage with the CometChip and mutagenesis by Duplex Sequencing. Environ Mol Mutagen. 2021 06; 62(5):306-318.
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Maura F, Weinhold N, Diamond B, Kazandjian D, Rasche L, Morgan G, Landgren O. The mutagenic impact of melphalan in multiple myeloma. Leukemia. 2021 08; 35(8):2145-2150.
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H?lzl-Armstrong L, Kucab JE, Zwart EP, Luijten M, Phillips DH, Arlt VM. Mutagenicity of N-hydroxy-4-aminobiphenyl in human TP53 knock-in (Hupki) mouse embryo fibroblasts. Environ Mol Mutagen. 2021 04; 62(4):252-264.
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H?lzl-Armstrong L, N?visdal A, Cox JA, Long AS, Chepelev NL, Phillips DH, White PA, Arlt VM. In vitro mutagenicity of selected environmental carcinogens and their metabolites in MutaMouse FE1 lung epithelial cells. Mutagenesis. 2020 12 31; 35(6):453-463.
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H?lzl-Armstrong L, Kucab JE, Moody S, Zwart EP, Loutkotov? L, Duffy V, Luijten M, Gamboa da Costa G, Stratton MR, Phillips DH, Arlt VM. Mutagenicity of acrylamide and glycidamide in human TP53 knock-in (Hupki) mouse embryo fibroblasts. Arch Toxicol. 2020 12; 94(12):4173-4196.
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Ramaker RC, Hardigan AA, Goh ST, Partridge EC, Wold B, Cooper SJ, Myers RM. Dissecting the regulatory activity and sequence content of loci with exceptional numbers of transcription factor associations. Genome Res. 2020 07; 30(7):939-950.
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Butler TJ, Estep KN, Sommers JA, Maul RW, Moore AZ, Bandinelli S, Cucca F, Tuke MA, Wood AR, Bharti SK, Bogenhagen DF, Yakubovskaya E, Garcia-Diaz M, Guilliam TA, Byrd AK, Raney KD, Doherty AJ, Ferrucci L, Schlessinger D, Ding J, Brosh RM. Mitochondrial genetic variation is enriched in G-quadruplex regions that stall DNA synthesis in vitro. Hum Mol Genet. 2020 05 28; 29(8):1292-1309.
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Su N, Byrd AK, Bharath SR, Yang O, Jia Y, Tang X, Ha T, Raney KD, Song H. Structural basis for DNA unwinding at forked dsDNA by two coordinating Pif1 helicases. Nat Commun. 2019 11 26; 10(1):5375.
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Kucab JE, Zou X, Morganella S, Joel M, Nanda AS, Nagy E, Gomez C, Degasperi A, Harris R, Jackson SP, Arlt VM, Phillips DH, Nik-Zainal S. A Compendium of Mutational Signatures of Environmental Agents. Cell. 2019 05 02; 177(4):821-836.e16.
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Walker BA, Mavrommatis K, Wardell CP, Ashby TC, Bauer M, Davies FE, Rosenthal A, Wang H, Qu P, Hoering A, Samur M, Towfic F, Ortiz M, Flynt E, Yu Z, Yang Z, Rozelle D, Obenauer J, Trotter M, Auclair D, Keats J, Bolli N, Fulciniti M, Szalat R, Moreau P, Durie B, Stewart AK, Goldschmidt H, Raab MS, Einsele H, Sonneveld P, San Miguel J, Lonial S, Jackson GH, Anderson KC, Avet-Loiseau H, Munshi N, Thakurta A, Morgan GJ. Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma. Blood. 2018 08 09; 132(6):587-597.
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Zheng JH, Grace CR, Guibao CD, McNamara DE, Llambi F, Wang YM, Chen T, Moldoveanu T. Intrinsic Instability of BOK Enables Membrane Permeabilization in Apoptosis. Cell Rep. 2018 05 15; 23(7):2083-2094.e6.
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Salinas E, Gupta A, Sifford JM, Oldenburg DG, White DW, Forrest JC. Conditional mutagenesis in vivo reveals cell type- and infection stage-specific requirements for LANA in chronic MHV68 infection. PLoS Pathog. 2018 01; 14(1):e1006865.
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Latham JI, Blevins JS. Generation of Conditional Mutants in Borrelia burgdorferi. Methods Mol Biol. 2018; 1690:225-239.
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Peng Y, Shinde DN, Valencia CA, Mo JS, Rosenfeld J, Truitt Cho M, Chamberlin A, Li Z, Liu J, Gui B, Brockhage R, Basinger A, Alvarez-Leon B, Heydemann P, Magoulas PL, Lewis AM, Scaglia F, Gril S, Chong SC, Bower M, Monaghan KG, Willaert R, Plona MR, Dineen R, Milan F, Hoganson G, Powis Z, Helbig KL, Keller-Ramey J, Harris B, Anderson LC, Green T, Sukoff Rizzo SJ, Kaylor J, Chen J, Guan MX, Sellars E, Sparagana SP, Gibson JB, Reinholdt LG, Tang S, Huang T. Biallelic mutations in the ferredoxin reductase gene cause novel mitochondriopathy with optic atrophy. Hum Mol Genet. 2017 12 15; 26(24):4937-4950.
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Culbertson AT, Chou YH, Smith AL, Young ZT, Tietze AA, Cottaz S, Faur? R, Zabotina OA. Enzymatic Activity of Xyloglucan Xylosyltransferase 5. Plant Physiol. 2016 07; 171(3):1893-904.
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Kucab JE, Zwart EP, van Steeg H, Luijten M, Schmeiser HH, Phillips DH, Arlt VM. TP53 and lacZ mutagenesis induced by 3-nitrobenzanthrone in Xpa-deficient human TP53 knock-in mouse embryo fibroblasts. DNA Repair (Amst). 2016 Mar; 39:21-33.
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Nik-Zainal S, Kucab JE, Morganella S, Glodzik D, Alexandrov LB, Arlt VM, Weninger A, Hollstein M, Stratton MR, Phillips DH. The genome as a record of environmental exposure. Mutagenesis. 2015 Nov; 30(6):763-70.
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Lor VS, Starker CG, Voytas DF, Weiss D, Olszewski NE. Targeted mutagenesis of the tomato PROCERA gene using transcription activator-like effector nucleases. Plant Physiol. 2014 Nov; 166(3):1288-91.
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