 Clonal Evolution
"Clonal Evolution" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process of accumulation of genetic and epigenetic changes over time in individual cells and the effect of the changes on CELL PROLIFERATION.
| Descriptor ID |
D060965
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| MeSH Number(s) |
G04.299.350 G05.355.123
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Clonal Evolution".
Below are MeSH descriptors whose meaning is more specific than "Clonal Evolution".
This graph shows the total number of publications written about "Clonal Evolution" by people in UAMS Profiles by year, and whether "Clonal Evolution" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 0 | 1 | 1 | | 2023 | 0 | 1 | 1 | | 2021 | 1 | 1 | 2 | | 2020 | 1 | 0 | 1 | | 2019 | 3 | 0 | 3 | | 2018 | 2 | 0 | 2 | | 2017 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 | | 2015 | 2 | 0 | 2 | | 2014 | 3 | 1 | 4 | | 2012 | 1 | 1 | 2 |
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Below are the most recent publications written about "Clonal Evolution" by people in Profiles over the past ten years.
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Schinke C, Rasche L, Raab MS, Weinhold N. Impact of Clonal Heterogeneity in Multiple Myeloma. Hematol Oncol Clin North Am. 2024 04; 38(2):461-476.
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Schichman SA, Penton AL, Ghanta SN, Konda M, Papenhausen PR. B-lymphoblastic leukemia/lymphoma with MYC and BCL2 gene rearrangements shows evidence for clonal evolution and mitotic recombination. J Hematop. 2023 Jun; 16(2):111-117.
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Diamond B, Yellapantula V, Rustad EH, Maclachlan KH, Mayerhoefer M, Kaiser M, Morgan G, Landgren O, Maura F. Positive selection as the unifying force for clonal evolution in multiple myeloma. Leukemia. 2021 05; 35(5):1511-1515.
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Mohan M, Yarlagadda N, Szabo A, Singh A, Pina Oviedo S, Schinke C. Clinical characteristics of testicular extramedullary involvement in multiple myeloma. Am J Hematol. 2021 03 01; 96(3):E77-E81.
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Landau HJ, Yellapantula V, Diamond BT, Rustad EH, Maclachlan KH, Gundem G, Medina-Martinez J, Ossa JA, Levine MF, Zhou Y, Kappagantula R, Baez P, Attiyeh M, Makohon-Moore A, Zhang L, Boyle EM, Ashby C, Blaney P, Patel M, Zhang Y, Dogan A, Chung DJ, Giralt S, Lahoud OB, Peled JU, Scordo M, Shah G, Hassoun H, Korde NS, Lesokhin AM, Lu S, Mailankody S, Shah U, Smith E, Hultcrantz ML, Ulaner GA, van Rhee F, Morgan GJ, Landgren O, Papaemmanuil E, Iacobuzio-Donahue C, Maura F. Accelerated single cell seeding in relapsed multiple myeloma. Nat Commun. 2020 07 17; 11(1):3617.
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Maura F, Rustad EH, Yellapantula V, Luksza M, Hoyos D, Maclachlan KH, Diamond BT, Greenbaum BD, Morgan G, Lesokhin A, Papaemmanuil E, Landgren O. Role of AID in the temporal pattern of acquisition of driver mutations in multiple myeloma. Leukemia. 2020 05; 34(5):1476-1480.
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Munawar U, Rasche L, M?ller N, Vogt C, Da-Via M, Haertle L, Arampatzi P, Dietrich S, Roth M, Garitano-Trojaola A, Steinhardt MJ, Strifler S, Gallardo M, Martinez-Lopez J, Bargou RC, Heckel T, Einsele H, St?hmer T, Kort?m KM, Barrio S. Hierarchy of mono- and biallelic TP53 alterations in multiple myeloma cell fitness. Blood. 2019 09 05; 134(10):836-840.
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Jones JR, Weinhold N, Ashby C, Walker BA, Wardell C, Pawlyn C, Rasche L, Melchor L, Cairns DA, Gregory WM, Johnson D, Begum DB, Ellis S, Sherborne AL, Cook G, Kaiser MF, Drayson MT, Owen RG, Jackson GH, Davies FE, Greaves M, Morgan GJ. Clonal evolution in myeloma: the impact of maintenance lenalidomide and depth of response on the genetics and sub-clonal structure of relapsed disease in uniformly treated newly diagnosed patients. Haematologica. 2019 07; 104(7):1440-1450.
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Dutta AK, Fink JL, Grady JP, Morgan GJ, Mullighan CG, To LB, Hewett DR, Zannettino ACW. Subclonal evolution in disease progression from MGUS/SMM to multiple myeloma is characterised by clonal stability. Leukemia. 2019 02; 33(2):457-468.
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Gralewski JH, Post GR, van Rhee F, Yuan Y. Myeloid transformation of plasma cell myeloma: molecular evidence of clonal evolution revealed by next generation sequencing. Diagn Pathol. 2018 Feb 20; 13(1):15.
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Wagner-Johnston ND, Lensing S, Noy A, Ratner L, Henry D, Lee JY, Silver S, Faham M, Ambinder RF. High frequency of identical clonal immunoglobulin DNA in pre-treatment tumor and plasma from untreated patients with HIV-associated lymphoma: prospective multicenter trial of the AIDS malignancies consortium (AMC 064). Leuk Lymphoma. 2017 12; 58(12):2939-2942.
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Weinhold N, Ashby C, Rasche L, Chavan SS, Stein C, Stephens OW, Tytarenko R, Bauer MA, Meissner T, Deshpande S, Patel PH, Buzder T, Molnar G, Peterson EA, van Rhee F, Zangari M, Thanendrarajan S, Schinke C, Tian E, Epstein J, Barlogie B, Davies FE, Heuck CJ, Walker BA, Morgan GJ. Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma. Blood. 2016 09 29; 128(13):1735-44.
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Peterson EA, Bauer MA, Chavan SS, Ashby C, Weinhold N, Heuck CJ, Morgan GJ, Johann DJ. Enhancing cancer clonality analysis with integrative genomics. BMC Bioinformatics. 2015; 16 Suppl 13:S7.
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Nanaji NM, Chen QC, Singh Z, Ross DD, Elman AH, Zou YS. Concomitant bone marrow involvement by plasma cell myeloma and primary myelodysplastic syndrome with biclonal complex chromosome anomalies. Leuk Lymphoma. 2015; 56(8):2470-2.
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