 Histiocytosis, Langerhans-Cell
"Histiocytosis, Langerhans-Cell" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of disorders resulting from the abnormal proliferation of and tissue infiltration by LANGERHANS CELLS which can be detected by their characteristic Birbeck granules (X bodies), or by monoclonal antibody staining for their surface CD1 ANTIGENS. Langerhans-cell granulomatosis can involve a single organ, or can be a systemic disorder.
| Descriptor ID |
D006646
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| MeSH Number(s) |
C08.381.483.375 C15.604.250.400
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| Concept/Terms |
Histiocytosis, Langerhans-Cell- Histiocytosis, Langerhans-Cell
- Histiocytosis, Langerhans Cell
- Hand-Schueller-Christian Syndrome
- Hand Schueller Christian Syndrome
- Syndrome, Hand-Schueller-Christian
- Hand-Schüller-Christian Disease
- Disease, Hand-Schüller-Christian
- Hand Schüller Christian Disease
- Hand-Schüller-Christian Syndrome
- Hand Schüller Christian Syndrome
- Syndrome, Hand-Schüller-Christian
- Histiocytosis X
- Histiocytosis, Generalized
- Generalized Histiocytoses
- Generalized Histiocytosis
- Histiocytoses, Generalized
- Histiocytosis-X
- Langerhans Cell Histiocytosis
- Cell Histiocytoses, Langerhans
- Cell Histiocytosis, Langerhans
- Histiocytoses, Langerhans Cell
- Langerhans Cell Histiocytoses
- Langerhans-Cell Granulomatosis
- Granulomatosis, Langerhans-Cell
- Langerhans Cell Granulomatosis
- Langerhans-Cell Histiocytosis
- Letterer-Siwe Disease
- Disease, Letterer-Siwe
- Letterer Siwe Disease
- Non-Lipid Reticuloendotheliosis
- Non Lipid Reticuloendotheliosis
- Non-Lipid Reticuloendothelioses
- Reticuloendothelioses, Non-Lipid
- Reticuloendotheliosis, Non-Lipid
- Schueller-Christian Disease
- Disease, Schueller-Christian
- Schueller Christian Disease
- Systemic Aleukemic Reticuloendotheliosis
- Aleukemic Reticuloendothelioses, Systemic
- Aleukemic Reticuloendotheliosis, Systemic
- Reticuloendothelioses, Systemic Aleukemic
- Reticuloendotheliosis, Systemic Aleukemic
- Systemic Aleukemic Reticuloendothelioses
- Type 2 Histiocytosis
- Histiocytoses, Type 2
- Histiocytosis, Type 2
- Type 2 Histiocytoses
- Hand-Schueller-Christian Disease
- Disease, Hand-Schueller-Christian
- Hand Schueller Christian Disease
Pulmonary Histiocytosis X- Pulmonary Histiocytosis X
- Histiocytosis X, Pulmonary
- Pulmonary Langerhans Cell Granulomatosis
- Langerhans Cell Granulomatosis, Pulmonary
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Below are MeSH descriptors whose meaning is more general than "Histiocytosis, Langerhans-Cell".
Below are MeSH descriptors whose meaning is more specific than "Histiocytosis, Langerhans-Cell".
This graph shows the total number of publications written about "Histiocytosis, Langerhans-Cell" by people in UAMS Profiles by year, and whether "Histiocytosis, Langerhans-Cell" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 2 | 0 | 2 | | 2023 | 3 | 0 | 3 | | 2022 | 5 | 0 | 5 | | 2021 | 2 | 0 | 2 | | 2020 | 2 | 0 | 2 | | 2017 | 2 | 0 | 2 | | 2016 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2004 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 1998 | 1 | 1 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Histiocytosis, Langerhans-Cell" by people in Profiles over the past ten years.
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Bielamowicz K, Dimitrion P, Abla O, Bomken S, Campbell P, Collin M, Degar B, Diamond EL, Eckstein OS, El-Mallawany N, Fluchel M, Goyal G, Henry MM, Hermiston M, Hogarty M, Jeng M, Jubran R, Lubega J, Kumar A, Ladisch S, McClain KL, Merad M, Mi QS, Parsons DW, Peckham-Gregory E, Picarsic J, Prudowsky ZD, Rollins BJ, Shaw PH, Wistinghausen B, Rodriguez-Galindo C, Allen CE. Langerhans cell histiocytosis: NACHO update on progress, chaos, and opportunity on the path to rational cures. Cancer. 2024 Jul 15; 130(14):2416-2439.
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Cournoyer E, Ferrell J, Sharp S, Ray A, Jordan M, Dandoy C, Grimley M, Roy S, Lorsbach R, Merrow AC, Nelson A, Bartlett A, Picarsic J, Kumar A. Dabrafenib and trametinib in Langerhans cell histiocytosis and other histiocytic disorders. Haematologica. 2024 04 01; 109(4):1137-1148.
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Chang L, Lang M, Lin H, Cai H, Duan MH, Zhou DB, Cao XX. Phase 2 study using low dose cytarabine for adult patients with newly diagnosed Langerhans cell histiocytosis. Leukemia. 2024 Apr; 38(4):803-809.
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Lang M, Cai HC, Lin H, Chang L, Dai JW, Chen J, Duan MH, Zhou DB, Goyal G, Cao XX. Clinical features, genomic profiling, and outcomes of adult patients with unifocal Langerhans cell histiocytosis. Orphanet J Rare Dis. 2023 Nov 30; 18(1):372.
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Dai JW, Lin H, Chang L, Li J, Zhou DB, Cao XX. The clinical spectrum and prognostic factors of Erdheim-Chester disease and mixed Langerhans cell histiocytosis and Erdheim-Chester disease. Ann Hematol. 2023 Dec; 102(12):3335-3343.
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Han HX, Chang L, Lang M, Lin H, Li J, Duan MH, Zhou DB, Cao XX. Clinical characteristics, genomic profiling and outcomes of single system multifocal Langerhans cell histiocytosis in adults with bone involvement. Blood Cancer J. 2023 09 05; 13(1):135.
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Cai HC, Chen J, Liu T, Cai H, Duan MH, Li J, Zhou DB, Cao XX. Langerhans cell histiocytosis in adolescent patients: a single-centre retrospective study. Orphanet J Rare Dis. 2022 07 15; 17(1):268.
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Cai HC, Liu T, Cai H, Duan MH, Li J, Zhou DB, Cao XX. Adult Langerhans cell histiocytosis with thyroid gland involvement: clinical presentation, genomic analysis, and outcome. Ann Hematol. 2022 Sep; 101(9):1925-1929.
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Wang JN, Liu T, Zhao AL, Pan BJ, Sun J, Li J, Zhou DB, Cao XX, Duan MH. Phase 2 study of oral thalidomide-cyclophosphamide-dexamethasone for recurrent/refractory adult Langerhans cell histiocytosis. Leukemia. 2022 06; 36(6):1619-1624.
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Zhao AL, Cai H, Chen J, Duan MH, Zhou DB, Li J, Cao XX. The potential of cell-free DNA to reveal the molecular profiles of Langerhans cell histiocytosis and Erdheim-Chester disease in adults. Leukemia. 2022 05; 36(5):1412-1415.
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Liu T, Cai HC, Cai H, Chen M, Zhang W, Li J, Zhou DB, Cao XX. Intermediate-dose cytarabine is an effective therapy for adults with non-Langerhans cell histiocytosis. Orphanet J Rare Dis. 2022 02 07; 17(1):39.
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Cao XX, Duan MH, Zhao AL, Cai H, Chen J, Gao XM, Liu T, Cai HC, Zhang L, Sun J, Liang ZY, Zhou DB, Li J. Treatment outcomes and prognostic factors of patients with adult Langerhans cell histiocytosis. Am J Hematol. 2022 02 01; 97(2):203-208.
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Wang JN, Wang FD, Sun J, Liang ZY, Li J, Zhou DB, Tian X, Cao XX. Pulmonary manifestations of Erdheim-Chester disease: clinical characteristics, outcomes and comparison with Langerhans cell histiocytosis. Br J Haematol. 2021 09; 194(6):1024-1033.
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Miao HL, Zhao AL, Duan MH, Zhou DB, Cao XX, Li J. Clinical presentation and prognostic analysis of adult patients with Langerhans cell histiocytosis with pulmonary involvement. BMC Cancer. 2020 Sep 23; 20(1):911.
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Cao XX, Li J, Zhao AL, He TH, Gao XM, Cai HC, Zhang L, Zhang Y, Feng J, Zhu TN, Niu N, Sun J, Liang ZY, Duan MH, Zhou DB. Methotrexate and cytarabine for adult patients with newly diagnosed Langerhans cell histiocytosis: A single arm, single center, prospective phase 2 study. Am J Hematol. 2020 09; 95(9):E235-E238.
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Lee LH, Krupski C, Clark J, Wunderlich M, Lorsbach RB, Grimley MS, Burwinkel M, Nelson A, Kumar AR. High-risk LCH in infants is serially transplantable in a xenograft model but responds durably to targeted therapy. Blood Adv. 2020 02 25; 4(4):717-727.
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Pina-Oviedo S, Torres-Cabala CA, Miranda RN, Tetzlaff MT, Singh S, Rapini RP, Prieto VG, Aung PP. Concomitant Cutaneous Langerhans Cell Hystiocytosis and Leukemia Cutis. Am J Dermatopathol. 2017 May; 39(5):388-392.
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Pina-Oviedo S, Medeiros LJ, Li S, Khoury JD, Patel KP, Alayed K, Cason RC, Bowman CJ, Yin CC. Langerhans cell histiocytosis associated with lymphoma: an incidental finding that is not associated with BRAF or MAP2K1 mutations. Mod Pathol. 2017 05; 30(5):734-744.
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Al-Mohannadi M, Yakoub R, Soofi ME, Elsabah HM, Thandassery RB. Gastrointestinal: Letterer Siwe disease: An uncommon gastrointestinal presentation. J Gastroenterol Hepatol. 2016 Jun; 31(6):1070.
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Stine KC. Risk organ + LCH gets the one-two punch? Blood. 2015 Sep 17; 126(12):1399-400.
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