 Mechanotransduction, Cellular
"Mechanotransduction, Cellular" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process by which cells convert mechanical stimuli into a chemical response. It can occur in both cells specialized for sensing mechanical cues such as MECHANORECEPTORS, and in parenchymal cells whose primary function is not mechanosensory.
| Descriptor ID |
D040542
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| MeSH Number(s) |
G01.154.100.440 G01.595.100.440 G02.111.087.800.580 G02.149.115.800.580 G04.299.880.580
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| Concept/Terms |
Mechanotransduction, Cellular- Mechanotransduction, Cellular
- Signal Transduction, Mechanical
- Mechanical Signal Transduction
- Mechanosensory Transduction
- Transduction, Mechanosensory
- Cellular Mechanotransduction
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Below are MeSH descriptors whose meaning is more general than "Mechanotransduction, Cellular".
Below are MeSH descriptors whose meaning is more specific than "Mechanotransduction, Cellular".
This graph shows the total number of publications written about "Mechanotransduction, Cellular" by people in UAMS Profiles by year, and whether "Mechanotransduction, Cellular" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2023 | 1 | 0 | 1 | | 2022 | 0 | 1 | 1 | | 2021 | 4 | 1 | 5 | | 2020 | 0 | 3 | 3 | | 2019 | 0 | 1 | 1 | | 2017 | 1 | 1 | 2 | | 2016 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2013 | 2 | 0 | 2 | | 2012 | 0 | 1 | 1 | | 2011 | 2 | 1 | 3 | | 2010 | 0 | 1 | 1 | | 2009 | 1 | 0 | 1 | | 2008 | 0 | 1 | 1 | | 2007 | 2 | 0 | 2 | | 2006 | 2 | 0 | 2 | | 2003 | 0 | 1 | 1 |
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Below are the most recent publications written about "Mechanotransduction, Cellular" by people in Profiles over the past ten years.
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Li X, Zhang C, Bowman HH, Stambough JB, Stronach BM, Mears SC, Barnes LC, Ambrogini E, Xiong J. Piezo1 opposes age-associated cortical bone loss. Aging Cell. 2023 06; 22(6):e13846.
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Reyes-Pardo H, S?nchez-Herrera DP, Santill?n M. On the effects of diabetes mellitus on the mechanical properties of DRG sensory neurons and their possible relation with diabetic neuropathy. Phys Biol. 2022 05 10; 19(4).
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Joshi R, Batie MR, Fan Q, Varisco BM. Mouse lung organoid responses to reduced, increased, and cyclic stretch. Am J Physiol Lung Cell Mol Physiol. 2022 01 01; 322(1):L162-L173.
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Dole NS, Yoon J, Monteiro DA, Yang J, Mazur CM, Kaya S, Belair CD, Alliston T. Mechanosensitive miR-100 coordinates TGF? and Wnt signaling in osteocytes during fluid shear stress. FASEB J. 2021 10; 35(10):e21883.
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Martinez A, Buckley M, Scalise CB, Katre AA, Dholakia JJ, Crossman D, Birrer MJ, Berry JL, Arend RC. Understanding the effect of mechanical forces on ovarian cancer progression. Gynecol Oncol. 2021 07; 162(1):154-162.
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Bailey KN, Nguyen J, Yee CS, Dole NS, Dang A, Alliston T. Mechanosensitive Control of Articular Cartilage and Subchondral Bone Homeostasis in Mice Requires Osteocytic Transforming Growth Factor ? Signaling. Arthritis Rheumatol. 2021 03; 73(3):414-425.
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Li X, Kordsmeier J, Xiong J. New Advances in Osteocyte Mechanotransduction. Curr Osteoporos Rep. 2021 02; 19(1):101-106.
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Liu S, Deng X, Zhang P, Wang X, Fan Y, Zhou S, Mu S, Mehta JL, Ding Z. Blood flow patterns regulate PCSK9 secretion via MyD88-mediated pro-inflammatory cytokines. Cardiovasc Res. 2020 08 01; 116(10):1721-1732.
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Hill JR, Eekhoff JD, Brophy RH, Lake SP. Elastic fibers in orthopedics: Form and function in tendons and ligaments, clinical implications, and future directions. J Orthop Res. 2020 11; 38(11):2305-2317.
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Ding Z, Pothineni NVK, Goel A, L?scher TF, Mehta JL. PCSK9 and inflammation: role of shear stress, pro-inflammatory cytokines, and LOX-1. Cardiovasc Res. 2020 04 01; 116(5):908-915.
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Reyes-Pardo H, S?nchez-Herrera DP. Mechanosensitive ion channel inhibitors promote the stiffening of the plasma membrane of mouse sensory neurons. Soft Matter. 2019 Oct 23; 15(41):8320-8328.
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Quach ME, Dragovich MA, Chen W, Syed AK, Cao W, Liang X, Deng W, De Meyer SF, Zhu G, Peng J, Ni H, Bennett CM, Hou M, Ware J, Deckmyn H, Zhang XF, Li R. Fc-independent immune thrombocytopenia via mechanomolecular signaling in platelets. Blood. 2018 02 15; 131(7):787-796.
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Perez J, Diaz N, Tandon I, Plate R, Martindale C, Balachandran K. Elevated Serotonin Interacts with Angiotensin-II to Result in Altered Valve Interstitial Cell Contractility and Remodeling. Cardiovasc Eng Technol. 2018 06; 9(2):168-180.
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Plotkin LI, Bellido T. Osteocytic signalling pathways as therapeutic targets for bone fragility. Nat Rev Endocrinol. 2016 Oct; 12(10):593-605.
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Young SM, Liu S, Joshi R, Batie MR, Kofron M, Guo J, Woods JC, Varisco BM. Localization and stretch-dependence of lung elastase activity in development and compensatory growth. J Appl Physiol (1985). 2015 Apr 01; 118(7):921-31.
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