 Receptor, Melanocortin, Type 4
"Receptor, Melanocortin, Type 4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A melanocortin receptor subtype found primarily in BRAIN. It shows specificity for ALPHA-MSH; BETA-MSH and ADRENOCORTICOTROPIC HORMONE.
| Descriptor ID |
D044105
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| MeSH Number(s) |
D12.776.543.750.100.430.937 D12.776.543.750.720.600.285.500.937 D12.776.543.750.750.555.285.500.937 D12.776.543.750.750.660.285.500.937
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| Concept/Terms |
Receptor, Melanocortin, Type 4- Receptor, Melanocortin, Type 4
- Melanocortin Receptor 4
- Receptor 4, Melanocortin
- Receptor, Melanocortin-4
- Melanocortin 4 Receptor
- Receptor, Melanocortin 4
- Melanocortin-4 Receptor
- MC4 Receptor
- Receptor, MC4
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Below are MeSH descriptors whose meaning is more general than "Receptor, Melanocortin, Type 4".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.100]
- Receptors, Melanocortin [D12.776.543.750.100.430]
- Receptor, Melanocortin, Type 4 [D12.776.543.750.100.430.937]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Neuropeptide [D12.776.543.750.720.600]
- Receptors, Corticotropin [D12.776.543.750.720.600.285]
- Receptors, Melanocortin [D12.776.543.750.720.600.285.500]
- Receptor, Melanocortin, Type 4 [D12.776.543.750.720.600.285.500.937]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Neuropeptide [D12.776.543.750.750.555]
- Receptors, Corticotropin [D12.776.543.750.750.555.285]
- Receptors, Melanocortin [D12.776.543.750.750.555.285.500]
- Receptor, Melanocortin, Type 4 [D12.776.543.750.750.555.285.500.937]
- Receptors, Pituitary Hormone [D12.776.543.750.750.660]
- Receptors, Corticotropin [D12.776.543.750.750.660.285]
- Receptors, Melanocortin [D12.776.543.750.750.660.285.500]
- Receptor, Melanocortin, Type 4 [D12.776.543.750.750.660.285.500.937]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Melanocortin, Type 4".
This graph shows the total number of publications written about "Receptor, Melanocortin, Type 4" by people in UAMS Profiles by year, and whether "Receptor, Melanocortin, Type 4" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 1 | 0 | 1 | | 2019 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2014 | 2 | 0 | 2 | | 2013 | 1 | 0 | 1 | | 2012 | 2 | 0 | 2 | | 2011 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2006 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptor, Melanocortin, Type 4" by people in Profiles over the past ten years.
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Griffin H, Hanson J, Phelan KD, Baldini G. MC4R Localizes at Excitatory Postsynaptic and Peri-Postsynaptic Sites of Hypothalamic Neurons in Primary Culture. Cells. 2024 Jul 23; 13(15).
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Baldini G, Phelan KD. The melanocortin pathway and control of appetite-progress and therapeutic implications. J Endocrinol. 2019 04 01; 241(1):R1-R33.
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Cooney KA, Molden BM, Kowalczyk NS, Russell S, Baldini G. Lipid stress inhibits endocytosis of melanocortin-4 receptor from modified clathrin-enriched sites and impairs receptor desensitization. J Biol Chem. 2017 10 27; 292(43):17731-17745.
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Molden BM, Cooney KA, West K, Van Der Ploeg LH, Baldini G. Temporal cAMP Signaling Selectivity by Natural and Synthetic MC4R Agonists. Mol Endocrinol. 2015 Nov; 29(11):1619-33.
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Bazzi MD, Nasr FA, Alanazi MS, Alamri A, Turjoman AA, Moustafa AS, Alfadda AA, Pathan AA, Parine NR. Association between FTO, MC4R, SLC30A8, and KCNQ1 gene variants and type 2 diabetes in Saudi population. Genet Mol Res. 2014 Dec 04; 13(4):10194-203.
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