 Amino Acids, Essential
"Amino Acids, Essential" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Amino acids that are not synthesized by the human body in amounts sufficient to carry out physiological functions. They are obtained from dietary foodstuffs.
| Descriptor ID |
D000601
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| MeSH Number(s) |
D12.125.142
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Amino Acids, Essential".
Below are MeSH descriptors whose meaning is more specific than "Amino Acids, Essential".
This graph shows the total number of publications written about "Amino Acids, Essential" by people in UAMS Profiles by year, and whether "Amino Acids, Essential" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2024 | 3 | 1 | 4 | | 2023 | 1 | 0 | 1 | | 2022 | 1 | 3 | 4 | | 2021 | 5 | 2 | 7 | | 2020 | 5 | 0 | 5 | | 2019 | 1 | 0 | 1 | | 2018 | 2 | 0 | 2 | | 2017 | 2 | 1 | 3 | | 2016 | 2 | 2 | 4 | | 2015 | 2 | 0 | 2 | | 2014 | 1 | 1 | 2 | | 2013 | 2 | 0 | 2 | | 2012 | 1 | 1 | 2 | | 2009 | 3 | 0 | 3 | | 2008 | 3 | 0 | 3 | | 2007 | 2 | 2 | 4 | | 2006 | 1 | 0 | 1 | | 2005 | 2 | 0 | 2 | | 2004 | 3 | 1 | 4 | | 2003 | 3 | 0 | 3 | | 2002 | 1 | 0 | 1 |
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Below are the most recent publications written about "Amino Acids, Essential" by people in Profiles over the past ten years.
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Starck CS, Wolfe RR, Moughan PJ. Toward a Dynamic Model of Indispensable Amino Acid Requirements of the Adult Human: A Factorial Estimate of Oxidative Amino Acid Losses. J Nutr. 2025 Jan; 155(1):338-352.
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Gwin JA, Church DD, Allen JT, Wilson MA, Carrigan CT, Murphy NE, Varanoske AN, Margolis LM, Wolfe RR, Ferrando AA, Pasiakos SM. Consuming Whey Protein with Added Essential Amino Acids, Not Carbohydrate, Maintains Postexercise Anabolism While Underfed. Med Sci Sports Exerc. 2025 Jan 01; 57(1):70-80.
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Jang J, Kim Y, Song T, Park S, Kim HJ, Koh JH, Cho Y, Park SY, Sadayappan S, Kwak HB, Wolfe RR, Kim IY, Choi CS. Free essential amino acid feeding improves endurance during resistance training via DRP1-dependent mitochondrial remodelling. J Cachexia Sarcopenia Muscle. 2024 Oct; 15(5):1651-1663.
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Azhar G, Verma A, Robeson MS, Patyal P, Nookaew I, Sharma S, Pangle A, Che Y, Wolfe RR, Wei JY. Short-Term Ingestion of Essential Amino Acid Based Nutritional Supplements or Whey Protein Improves the Physical Function of Older Adults Independently of Gut Microbiome. Mol Nutr Food Res. 2024 Mar; 68(6):e2300716.
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Azhar G, Verma A, Zhang X, Pangle A, Patyal P, Zhang W, Che Y, Coker K, Wolfe RR, Wei JY. Differential plasma protein expression after ingestion of essential amino acid-based dietary supplement verses whey protein in low physical functioning older adults. Geroscience. 2023 06; 45(3):1729-1743.
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Wolfe RR, Kim IY, Park S, Ferrando A. Tracing metabolic flux to assess optimal dietary protein and amino acid consumption. Exp Mol Med. 2022 09; 54(9):1323-1331.
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Jang J, Koh JH, Kim Y, Kim HJ, Park S, Chang Y, Jung J, Wolfe RR, Kim IY. Balanced Free Essential Amino Acids and Resistance Exercise Training Synergistically Improve Dexamethasone-Induced Impairments in Muscle Strength, Endurance, and Insulin Sensitivity in Mice. Int J Mol Sci. 2022 Aug 27; 23(17).
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Coker MS, Barati Z, Murphy CJ, Bateman T, Newcomer BR, Wolfe RR, Coker RH. Essential amino acid enriched meal replacement improves body composition and physical function in obese older adults: A randomized controlled trial. Clin Nutr ESPEN. 2022 10; 51:104-111.
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Park S, Chang Y, Wolfe RR, Kim IY. Prevention of Loss of Muscle Mass and Function in Older Adults during COVID-19 Lockdown: Potential Role of Dietary Essential Amino Acids. Int J Environ Res Public Health. 2022 07 01; 19(13).
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Coker MS, Schutzler SE, Park S, Williams RH, Ferrando AA, Deutz NEP, Wolfe RR, Coker RH. Equivalent servings of free-range reindeer promote greater net protein balance compared to commercial beef. Int J Circumpolar Health. 2021 12; 80(1):1897222.
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Hirsch KR, Greenwalt CE, Cabre HE, Gould LM, Brewer GJ, Blue MNM, Ferrando AA, Huffman KM, Mayer-Davis EJ, Ryan ED, Smith-Ryan AE. Metabolic effects of high-intensity interval training and essential amino acids. Eur J Appl Physiol. 2021 Dec; 121(12):3297-3311.
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Azhar G, Wei JY, Schutzler SE, Coker K, Gibson RV, Kirby MF, Ferrando AA, Wolfe RR. Daily Consumption of a Specially Formulated Essential Amino Acid-Based Dietary Supplement Improves Physical Performance in Older Adults With Low Physical Functioning. J Gerontol A Biol Sci Med Sci. 2021 06 14; 76(7):1184-1191.
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Hirsch KR, Wolfe RR, Ferrando AA. Pre- and Post-Surgical Nutrition for Preservation of Muscle Mass, Strength, and Functionality Following Orthopedic Surgery. Nutrients. 2021 May 15; 13(5).
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Jang J, Park S, Kim Y, Jung J, Lee J, Chang Y, Lee SP, Park BC, Wolfe RR, Choi CS, Kim IY. Myostatin Inhibition-Induced Increase in Muscle Mass and Strength Was Amplified by Resistance Exercise Training, and Dietary Essential Amino Acids Improved Muscle Quality in Mice. Nutrients. 2021 Apr 29; 13(5).
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Gwin JA, Church DD, Hatch-McChesney A, Allen JT, Wilson MA, Varanoske AN, Carrigan CT, Murphy NE, Margolis LM, Carbone JW, Wolfe RR, Ferrando AA, Pasiakos SM. Essential amino acid-enriched whey enhances post-exercise whole-body protein balance during energy deficit more than iso-nitrogenous whey or a mixed-macronutrient meal: a randomized, crossover study. J Int Soc Sports Nutr. 2021 Jan 07; 18(1):4.
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Hirsch KR, Greenwalt CE, Saylor HE, Gould LM, Harrison CH, Brewer GJ, Blue MNM, Ferrando AA, Huffman KM, Mayer-Davis EJ, Ryan ED, Smith-Ryan AE. High-intensity interval training and essential amino acid supplementation: Effects on muscle characteristics and whole-body protein turnover. Physiol Rep. 2021 01; 9(1):e14655.
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Church DD, Hirsch KR, Park S, Kim IY, Gwin JA, Pasiakos SM, Wolfe RR, Ferrando AA. Essential Amino Acids and Protein Synthesis: Insights into Maximizing the Muscle and Whole-Body Response to Feeding. Nutrients. 2020 Dec 02; 12(12).
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Gwin JA, Church DD, Wolfe RR, Ferrando AA, Pasiakos SM. Muscle Protein Synthesis and Whole-Body Protein Turnover Responses to Ingesting Essential Amino Acids, Intact Protein, and Protein-Containing Mixed Meals with Considerations for Energy Deficit. Nutrients. 2020 Aug 15; 12(8).
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Gwin JA, Church DD, Hatch-McChesney A, Howard EE, Carrigan CT, Murphy NE, Wilson MA, Margolis LM, Carbone JW, Wolfe RR, Ferrando AA, Pasiakos SM. Effects of high versus standard essential amino acid intakes on whole-body protein turnover and mixed muscle protein synthesis during energy deficit: A randomized, crossover study. Clin Nutr. 2021 03; 40(3):767-777.
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Park S, Church DD, Azhar G, Schutzler SE, Ferrando AA, Wolfe RR. Anabolic response to essential amino acid plus whey protein composition is greater than whey protein alone in young healthy adults. J Int Soc Sports Nutr. 2020 Feb 10; 17(1):9.
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Coker MS, Ladd KR, Kim J, Murphy CJ, DeCort R, Newcomer BR, Wolfe RR, Coker RH. Essential Amino Acid Supplement Lowers Intrahepatic Lipid despite Excess Alcohol Consumption. Nutrients. 2020 Jan 19; 12(1).
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Kim IY, Park S, Smeets ETHC, Schutzler S, Azhar G, Wei JY, Ferrando AA, Wolfe RR. Consumption of a Specially-Formulated Mixture of Essential Amino Acids Promotes Gain in Whole-Body Protein to a Greater Extent than a Complete Meal Replacement in Older Women with Heart Failure. Nutrients. 2019 Jun 17; 11(6).
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Coker RH, Shin K, Scholten K, Johannsen M, Tsigonis J, Kim IY, Schutzler SE, Wolfe RR. Essential amino acid-enriched meal replacement promotes superior net protein balance in older, overweight adults. Clin Nutr. 2019 12; 38(6):2821-2826.
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Dijk FJ, van Dijk M, Walrand S, van Loon LJC, van Norren K, Luiking YC. Differential effects of leucine and leucine-enriched whey protein on skeletal muscle protein synthesis in aged mice. Clin Nutr ESPEN. 2018 04; 24:127-133.
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Wolfe RR, Baum JI, Starck C, Moughan PJ. Factors contributing to the selection of dietary protein food sources. Clin Nutr. 2018 02; 37(1):130-138.
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Kim IY, Shin YA, Schutzler SE, Azhar G, Wolfe RR, Ferrando AA. Quality of meal protein determines anabolic response in older adults. Clin Nutr. 2018 12; 37(6 Pt A):2076-2083.
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J?ger R, Kerksick CM, Campbell BI, Cribb PJ, Wells SD, Skwiat TM, Purpura M, Ziegenfuss TN, Ferrando AA, Arent SM, Smith-Ryan AE, Stout JR, Arciero PJ, Ormsbee MJ, Taylor LW, Wilborn CD, Kalman DS, Kreider RB, Willoughby DS, Hoffman JR, Krzykowski JL, Antonio J. International Society of Sports Nutrition Position Stand: protein and exercise. J Int Soc Sports Nutr. 2017; 14:20.
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Jonker R, Deutz NE, Erbland ML, Anderson PJ, Engelen MP. Effectiveness of essential amino acid supplementation in stimulating whole body net protein anabolism is comparable between COPD patients and healthy older adults. Metabolism. 2017 Apr; 69:120-129.
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Kramer IF, Verdijk LB, Hamer HM, Verlaan S, Luiking YC, Kouw IWK, Senden JM, van Kranenburg J, Gijsen AP, Bierau J, Poeze M, van Loon LJC. Both basal and post-prandial muscle protein synthesis rates, following the ingestion of a leucine-enriched whey protein supplement, are not impaired in sarcopenic older males. Clin Nutr. 2017 10; 36(5):1440-1449.
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Wolfe RR, Rutherfurd SM, Kim IY, Moughan PJ. Protein quality as determined by the Digestible Indispensable Amino Acid Score: evaluation of factors underlying the calculation. Nutr Rev. 2016 09; 74(9):584-99.
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Baum JI, Kim IY, Wolfe RR. Protein Consumption and the Elderly: What Is the Optimal Level of Intake? Nutrients. 2016 Jun 08; 8(6).
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