 Amino Acid Chloromethyl Ketones
"Amino Acid Chloromethyl Ketones" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Inhibitors of SERINE ENDOPEPTIDASES and sulfhydryl group-containing enzymes. They act as alkylating agents and are known to interfere in the translation process.
| Descriptor ID |
D000590
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| MeSH Number(s) |
D12.125.065
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Amino Acid Chloromethyl Ketones".
Below are MeSH descriptors whose meaning is more specific than "Amino Acid Chloromethyl Ketones".
This graph shows the total number of publications written about "Amino Acid Chloromethyl Ketones" by people in UAMS Profiles by year, and whether "Amino Acid Chloromethyl Ketones" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2013 | 0 | 1 | 1 | | 2012 | 1 | 0 | 1 | | 2005 | 0 | 2 | 2 | | 2003 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 |
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Below are the most recent publications written about "Amino Acid Chloromethyl Ketones" by people in Profiles over the past ten years.
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Ni HM, McGill MR, Chao X, Woolbright BL, Jaeschke H, Ding WX. Caspase Inhibition Prevents Tumor Necrosis Factor-a-Induced Apoptosis and Promotes Necrotic Cell Death in Mouse Hepatocytes in?Vivo and in?Vitro. Am J Pathol. 2016 10; 186(10):2623-36.
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Woolbright BL, McGill MR, Yan H, Jaeschke H. Bile Acid-Induced Toxicity in HepaRG Cells Recapitulates the Response in Primary Human Hepatocytes. Basic Clin Pharmacol Toxicol. 2016 Feb; 118(2):160-7.
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