 Tryptophan
"Tryptophan" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An essential amino acid that is necessary for normal growth in infants and for NITROGEN balance in adults. It is a precursor of INDOLE ALKALOIDS in plants. It is a precursor of SEROTONIN (hence its use as an antidepressant and sleep aid). It can be a precursor to NIACIN, albeit inefficiently, in mammals.
| Descriptor ID |
D014364
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| MeSH Number(s) |
D12.125.072.050.850 D12.125.142.875
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| Concept/Terms |
Tryptophan- Tryptophan
- L-Tryptophan
- L Tryptophan
- Levotryptophan
Ardeydorm- Ardeydorm
- Ardeytropin
- Ardeypharm Brand of Tryptophan
L-Tryptophan-ratiopharm- L-Tryptophan-ratiopharm
- L Tryptophan ratiopharm
- Ratiopharm Brand of Tryptophan
- ratio-Tryptophan
- ratio Tryptophan
PMS-Tryptophan- PMS-Tryptophan
- PMS Tryptophan
- Pharmascience Brand of Tryptophan
Trofan- Trofan
- Upsher-Smith Brand of Tryptophan
Optimax- Optimax
- Merck Brand of Tryptophan
Lyphan- Lyphan
- Naturruhe
- esparma Brand of Tryptophan
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Below are MeSH descriptors whose meaning is more general than "Tryptophan".
Below are MeSH descriptors whose meaning is more specific than "Tryptophan".
This graph shows the total number of publications written about "Tryptophan" by people in UAMS Profiles by year, and whether "Tryptophan" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 1 | 0 | 1 | | 2022 | 0 | 1 | 1 | | 2021 | 1 | 0 | 1 | | 2019 | 0 | 1 | 1 | | 2017 | 3 | 0 | 3 | | 2015 | 2 | 0 | 2 | | 2013 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2011 | 4 | 0 | 4 | | 2010 | 2 | 0 | 2 | | 2009 | 2 | 1 | 3 | | 2008 | 2 | 1 | 3 | | 2007 | 1 | 0 | 1 | | 2006 | 7 | 0 | 7 | | 2005 | 1 | 3 | 4 | | 2004 | 3 | 0 | 3 | | 2003 | 1 | 1 | 2 | | 2002 | 6 | 1 | 7 | | 2000 | 3 | 3 | 6 | | 1999 | 6 | 0 | 6 | | 1998 | 1 | 1 | 2 | | 1996 | 4 | 1 | 5 | | 1995 | 3 | 0 | 3 | | 1994 | 3 | 1 | 4 | | 1993 | 1 | 0 | 1 | | 1992 | 2 | 0 | 2 | | 1991 | 2 | 0 | 2 | | 1990 | 1 | 2 | 3 | | 1989 | 3 | 1 | 4 |
To return to the timeline, click here.
Below are the most recent publications written about "Tryptophan" by people in Profiles over the past ten years.
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Luu HN, Pham YT, Yuan JM, Brand RE, Pham TV, Dao HV, Le CKT, Huynh NYN, Nguyen HM, Le NT. Tryptophan intake and pancreatic cancer: findings from a case-control study. Eur J Cancer Prev. 2024 Jul 01; 33(4):285-292.
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Joffr? E, Xiao X, Correia MSP, Nookaew I, Sasse S, Globisch D, Zhu B, Sj?ling ?. Analysis of Growth Phases of Enterotoxigenic Escherichia coli Reveals a Distinct Transition Phase before Entry into Early Stationary Phase with Shifts in Tryptophan, Fucose, and Putrescine Metabolism and Degradation of Neurotransmitter Precursors. Microbiol Spectr. 2022 08 31; 10(4):e0175521.
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Yusufu I, Ding K, Smith K, Wankhade UD, Sahay B, Patterson GT, Pacholczyk R, Adusumilli S, Hamrick MW, Hill WD, Isales CM, Fulzele S. A Tryptophan-Deficient Diet Induces Gut Microbiota Dysbiosis and Increases Systemic Inflammation in Aged Mice. Int J Mol Sci. 2021 May 08; 22(9).
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Alam M, Zameer S, Najmi AK, Ahmad FJ, Imam SS, Akhtar M. Thymoquinone Loaded Solid Lipid Nanoparticles Demonstrated Antidepressant-Like Activity in Rats via Indoleamine 2, 3- Dioxygenase Pathway. Drug Res (Stuttg). 2020 May; 70(5):206-213.
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Xin Y, Yue X, Li H, Li Z, Cai H, Choudhary AK, Zhang S, Chugani DC, Langhans SA. PET imaging of medulloblastoma with an 18F-labeled tryptophan analogue in a transgenic mouse model. Sci Rep. 2020 03 02; 10(1):3800.
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Yue X, Xin Y, Zhang S, Nikam R, Kandula V, Choudhary AK, Chugani HT, Chugani DC. Automated production of 1-(2-[18F]fluoroethyl)-l-tryptophan for imaging of tryptophan metabolism. Appl Radiat Isot. 2020 Feb; 156:109022.
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Huang JY, Larose TL, Luu HN, Wang R, Fanidi A, Alcala K, Stevens VL, Weinstein SJ, Albanes D, Caporaso NE, Purdue MP, Ziegler RG, Freedman ND, Lan Q, Prentice RL, Pettinger M, Thomson CA, Cai Q, Wu J, Blot WJ, Shu XO, Zheng W, Arslan AA, Zeleniuch-Jacquotte A, Le Marchand L, Wilkens LR, Haiman CA, Zhang X, Stampfer MJ, Han J, Giles GG, Hodge AM, Severi G, Johansson M, Grankvist K, Langhammer A, Hveem K, Xiang YB, Li HL, Gao YT, Visvanathan K, Ueland PM, Midttun ?, Ulvi A, Buring JE, Lee IM, Sesso HD, Gaziano JM, Manjer J, Relton C, Koh WP, Brennan P, Johansson M, Yuan JM. Circulating markers of cellular immune activation in prediagnostic blood sample and lung cancer risk in the Lung Cancer Cohort Consortium (LC3). Int J Cancer. 2020 05 01; 146(9):2394-2405.
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Fertan E, Rodrigues GJ, Wheeler RV, Goguen D, Wong AA, James H, Stadnyk A, Brown RE, Weaver ICG. Cognitive Decline, Cerebral-Spleen Tryptophan Metabolism, Oxidative Stress, Cytokine Production, and Regulation of the Txnip Gene in a Triple Transgenic Mouse Model of Alzheimer Disease. Am J Pathol. 2019 07; 189(7):1435-1450.
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Bagla S, Cukovic D, Asano E, Sood S, Luat A, Chugani HT, Chugani DC, Dombkowski AA. A distinct microRNA expression profile is associated with a[11C]-methyl-L-tryptophan (AMT) PET uptake in epileptogenic cortical tubers resected from patients with tuberous sclerosis complex. Neurobiol Dis. 2018 Jan; 109(Pt A):76-87.
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Saraf MK, Piccolo BD, Bowlin AK, Mercer KE, LeRoith T, Chintapalli SV, Shankar K, Badger TM, Yeruva L. Formula diet driven microbiota shifts tryptophan metabolism from serotonin to tryptamine in neonatal porcine colon?. Microbiome. 2017 07 14; 5(1):77.
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Lieben CK, Blokland A, Deutz NE, Jansen W, Han G, Hupperts RM. Intake of tryptophan-enriched whey protein acutely enhances recall of positive loaded words in patients with multiple sclerosis. Clin Nutr. 2018 02; 37(1):321-328.
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Weinstein JJ, Rogers BP, Taylor WD, Boyd BD, Cowan RL, Shelton KM, Salomon RM. Effects of acute tryptophan depletion on raph? functional connectivity in depression. Psychiatry Res. 2015 Nov 30; 234(2):164-71.
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Wang B, Lu F, Cheng Y, Chen JH, Jeon HY, Ha KS, Cao J, Nyunt MH, Han JH, Lee SK, Kyaw MP, Sattabongkot J, Takashima E, Tsuboi T, Han ET. Immunoprofiling of the tryptophan-rich antigen family in Plasmodium vivax. Infect Immun. 2015 Aug; 83(8):3083-95.
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