I-kappa B Kinase
 
																	
																		 
																	
																		
																	 
																	
																		 
																	
																		
																	 
																	
																			
																					
	"I-kappa B Kinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
 
	
	
		
			
			
				A protein serine-threonine kinase that catalyzes the PHOSPHORYLATION of I KAPPA B PROTEINS. This enzyme also activates the transcription factor NF-KAPPA B and is composed of alpha and beta catalytic subunits, which are protein kinases and gamma, a regulatory subunit.
    
			 
			
				
				
					
						| Descriptor ID | 
										
							D051550
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						| MeSH Number(s) | 
						
							 D08.811.913.696.620.682.700.494 D12.644.360.376 D12.776.476.378 
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						| Concept/Terms | 
						
							I-kappa B Kinase- I-kappa B Kinase
 - B Kinase, I-kappa
 - Kinase, I-kappa B
 - IkappaB Kinase
 - Kinase, IkappaB
 - NK-kappa B-Activating Kinase NAK
 - NK kappa B Activating Kinase NAK
 - I kappa B Kinase
 
  IkappaB Kinase gamma- IkappaB Kinase gamma
 - NF-kappaB Essential Modifier
 - Essential Modifier, NF-kappaB
 - NF kappaB Essential Modifier
 - IKK gamma
 
  IkappaB Kinase alpha- IkappaB Kinase alpha
 - Kinase alpha, IkappaB
 - Conserved Helix-Loop-Helix Ubiquitous Kinase
 - Conserved Helix Loop Helix Ubiquitous Kinase
 - IKK alpha
 - IkappaBalpha Kinase
 - IKK 1 Kinase
 - CHUK Kinase
 - I Kappa B alpha-Associated Protein Kinase
 - I Kappa B alpha Associated Protein Kinase
 
  
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				Below are MeSH descriptors whose meaning is more general than "I-kappa B Kinase". 
				
			 
			
			
				Below are MeSH descriptors whose meaning is more specific than "I-kappa B Kinase". 
				
			 
		 
	 
 
																				
																					
	
	
		
			
			
					
				This graph shows the total number of publications written about "I-kappa B Kinase" by people in UAMS Profiles by year, and whether "I-kappa B Kinase" was a major or minor topic of these publications.  
				
					 
                    To see the data from this visualization as text,  click here. 
				 
                
		            | Year | Major Topic | Minor Topic | Total | 
|---|
 | 2022 | 0 | 1 | 1 |  | 2021 | 1 | 0 | 1 |  | 2016 | 0 | 1 | 1 |  | 2015 | 0 | 1 | 1 |  | 2014 | 1 | 0 | 1 |  | 2012 | 0 | 1 | 1 |  | 2011 | 1 | 2 | 3 |  | 2010 | 1 | 2 | 3 |  | 2007 | 0 | 1 | 1 |  | 2005 | 0 | 1 | 1 |  
 
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				Below are the most recent publications written about "I-kappa B Kinase" by people in Profiles over the past ten years. 
						
					
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Sanford Kobayashi E, Batalov S, Wenger AM, Lambert C, Dhillon H, Hall RJ, Baybayan P, Ding Y, Rego S, Wigby K, Friedman J, Hobbs C, Bainbridge MN. Approaches to long-read sequencing in a clinical setting to improve diagnostic rate. Sci Rep. 2022 10 09; 12(1):16945. 
															
								 
							
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McCorkell KA, Jayachandran N, Cully MD, Freund-Brown J, Weinkopff T, Monslow J, Hu Y, Pur? E, Freedman BD, Alvarez JI, Cancro MP, May MJ. Lymph node formation and B cell homeostasis require IKK-a in distinct endothelial cell-derived compartments. Proc Natl Acad Sci U S A. 2021 11 30; 118(48). 
															
								 
							
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Liu M, Chen S, Yueh MF, Fujiwara R, Konopnicki C, Hao H, Tukey RH. Cadmium and arsenic override NF-?B developmental regulation of the intestinal UGT1A1 gene and control of hyperbilirubinemia. Biochem Pharmacol. 2016 06 15; 110-111:37-46. 
															
								 
							
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Mao X, Phanavanh B, Hamdan H, Moerman-Herzog AM, Barger SW. NF?B-inducing kinase inhibits NF?B activity specifically in neurons of the CNS. J Neurochem. 2016 Apr; 137(2):154-63. 
															
								 
							
				 	
			 	
			
			
		 
	 
 
       
																				
                                                                            
																		
																	 
																 
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