 Interleukin-8
"Interleukin-8" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the CXC chemokine family that plays a role in the regulation of the acute inflammatory response. It is secreted by variety of cell types and induces CHEMOTAXIS of NEUTROPHILS and other inflammatory cells.
| Descriptor ID |
D016209
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| MeSH Number(s) |
D12.644.276.374.200.120.800 D12.644.276.374.465.508 D12.776.467.374.200.120.800 D12.776.467.374.465.508 D23.125.300.120.800 D23.469.200.120.800 D23.529.374.200.120.800 D23.529.374.465.508
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| Concept/Terms |
Interleukin-8- Interleukin-8
- Interleukin 8
- IL8
- Monocyte-Derived Neutrophil Chemotactic Factor
- Neutrophil Activation Factor
- Neutrophil-Activating Peptide, Lymphocyte-Derived
- Lymphocyte-Derived Neutrophil-Activating Peptide
- Neutrophil Activating Peptide, Lymphocyte Derived
- Neutrophil-Activating Peptide, Monocyte-Derived
- Monocyte-Derived Neutrophil-Activating Peptide
- Neutrophil Activating Peptide, Monocyte Derived
- Alveolar Macrophage Chemotactic Factor-I
- Alveolar Macrophage Chemotactic Factor I
- Granulocyte Chemotactic Peptide-Interleukin-8
- Chemotactic Peptide-Interleukin-8, Granulocyte
- Granulocyte Chemotactic Peptide Interleukin 8
- Anionic Neutrophil-Activating Peptide
- Anionic Neutrophil Activating Peptide
- Neutrophil-Activating Peptide, Anionic
- Peptide, Anionic Neutrophil-Activating
- Chemokine CXCL8
- CXCL8, Chemokine
- Chemokines, CXCL8
- CXCL8 Chemokines
- Chemotactic Factor, Macrophage-Derived
- Chemotactic Factor, Macrophage Derived
- Macrophage-Derived Chemotactic Factor
- Chemotactic Factor, Neutrophil
- Neutrophil Chemotactic Factor
- Chemotactic Factor, Neutrophil, Monocyte-Derived
- CXCL8 Chemokine
- Chemokine, CXCL8
- IL-8
- AMCF-I
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Below are MeSH descriptors whose meaning is more general than "Interleukin-8".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-8".
This graph shows the total number of publications written about "Interleukin-8" by people in UAMS Profiles by year, and whether "Interleukin-8" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2022 | 0 | 2 | 2 | | 2019 | 0 | 2 | 2 | | 2017 | 1 | 0 | 1 | | 2016 | 0 | 3 | 3 | | 2015 | 1 | 6 | 7 | | 2014 | 2 | 1 | 3 | | 2013 | 0 | 3 | 3 | | 2012 | 1 | 2 | 3 | | 2011 | 0 | 1 | 1 | | 2010 | 3 | 2 | 5 | | 2009 | 0 | 2 | 2 | | 2008 | 0 | 2 | 2 | | 2007 | 1 | 0 | 1 | | 2006 | 0 | 3 | 3 | | 2005 | 1 | 8 | 9 | | 2004 | 0 | 1 | 1 | | 2003 | 4 | 0 | 4 | | 2002 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 | | 1998 | 0 | 1 | 1 | | 1997 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Interleukin-8" by people in Profiles over the past ten years.
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Scott XO, Chen SH, Hadad R, Yavagal D, Peterson EC, Starke RM, Dietrich WD, Keane RW, de Rivero Vaccari JP. Cohort study on the differential expression of inflammatory and angiogenic factors in thrombi, cerebral and peripheral plasma following acute large vessel occlusion stroke. J Cereb Blood Flow Metab. 2022 10; 42(10):1827-1839.
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Muehling LM, Heymann PW, Carper H, Murphy DD, Rajadhyaksha E, Kennedy J, Early SV, Soto-Quiros M, Avila L, Workman L, Platts-Mills TAE, Woodfolk JA. Cluster analysis of nasal cytokines during rhinovirus infection identifies different immunophenotypes in both children and adults with allergic asthma. Clin Exp Allergy. 2022 10; 52(10):1169-1182.
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Palangat M, Anastasakis DG, Fei DL, Lindblad KE, Bradley R, Hourigan CS, Hafner M, Larson DR. The splicing factor U2AF1 contributes to cancer progression through a noncanonical role in translation regulation. Genes Dev. 2019 05 01; 33(9-10):482-497.
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McCoin CS, Gillingham MB, Knotts TA, Vockley J, Ono-Moore KD, Blackburn ML, Norman JE, Adams SH. Blood cytokine patterns suggest a modest inflammation phenotype in subjects with long-chain fatty acid oxidation disorders. Physiol Rep. 2019 03; 7(6):e14037.
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Stephens KE, Levine JD, Aouizerat BE, Paul SM, Abrams G, Conley YP, Miaskowski C. Associations between genetic and epigenetic variations in cytokine genes and mild persistent breast pain in women following breast cancer surgery. Cytokine. 2017 11; 99:203-213.
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Farris RA, Price ET. Reverse Translational Study of Fenofibrate's Observed Effects in Diabetes-Associated Retinopathy. Clin Transl Sci. 2017 03; 10(2):110-116.
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Jajtner AR, Hoffman JR, Townsend JR, Beyer KS, Varanoske AN, Church DD, Oliveira LP, Herrlinger KA, Radom-Aizik S, Fukuda DH, Stout JR. The effect of polyphenols on cytokine and granulocyte response to resistance exercise. Physiol Rep. 2016 12; 4(24).
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Yeruva L, Spencer NE, Saraf MK, Hennings L, Bowlin AK, Cleves MA, Mercer K, Chintapalli SV, Shankar K, Rank RG, Badger TM, Ronis MJ. Formula diet alters small intestine morphology, microbial abundance and reduces VE-cadherin and IL-10 expression in neonatal porcine model. BMC Gastroenterol. 2016 Mar 22; 16:40.
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Prueitt RL, Wallace TA, Glynn SA, Yi M, Tang W, Luo J, Dorsey TH, Stagliano KE, Gillespie JW, Hudson RS, Terunuma A, Shoe JL, Haines DC, Yfantis HG, Han M, Martin DN, Jordan SV, Borin JF, Naslund MJ, Alexander RB, Stephens RM, Loffredo CA, Lee DH, Putluri N, Sreekumar A, Hurwitz AA, Ambs S. An Immune-Inflammation Gene Expression Signature in Prostate Tumors of Smokers. Cancer Res. 2016 Mar 01; 76(5):1055-1065.
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Ryu S, Johnson A, Park Y, Kim B, Norris D, Armstrong CA, Song PI. The Alpha-Melanocyte-Stimulating Hormone Suppresses TLR2-Mediated Functional Responses through IRAK-M in Normal Human Keratinocytes. PLoS One. 2015; 10(8):e0136887.
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Stolarz AJ, Farris RA, Wiley CA, O'Brien CE, Price ET. Fenofibrate Attenuates Neutrophilic Inflammation in Airway Epithelia: Potential Drug Repurposing for Cystic Fibrosis. Clin Transl Sci. 2015 Dec; 8(6):696-701.
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Ryu S, Han HM, Song PI, Armstrong CA, Park Y. Suppression of Propionibacterium acnes Infection and the Associated Inflammatory Response by the Antimicrobial Peptide P5 in Mice. PLoS One. 2015; 10(7):e0132619.
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Yeruva L, Bowlin AK, Spencer N, Maurelli AT, Rank RG. Chlamydial variants differ in ability to ascend the genital tract in the guinea pig model of chlamydial genital infection. Infect Immun. 2015 Aug; 83(8):3176-83.
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DelNero P, Lane M, Verbridge SS, Kwee B, Kermani P, Hempstead B, Stroock A, Fischbach C. 3D culture broadly regulates tumor cell hypoxia response and angiogenesis via pro-inflammatory pathways. Biomaterials. 2015 Jul; 55:110-8.
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Schinke C, Giricz O, Li W, Shastri A, Gordon S, Barreyro L, Barreryo L, Bhagat T, Bhattacharyya S, Ramachandra N, Bartenstein M, Pellagatti A, Boultwood J, Wickrema A, Yu Y, Will B, Wei S, Steidl U, Verma A. IL8-CXCR2 pathway inhibition as a therapeutic strategy against MDS and AML stem cells. Blood. 2015 May 14; 125(20):3144-52.
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Ryu S, Park Y, Kim B, Cho SM, Lee J, Lee HH, Gurley C, Song K, Johnson A, Armstrong CA, Song PI. Inhibitory and anti-inflammatory effects of the Helicobacter pylori-derived antimicrobial peptide HPA3NT3 against Propionibacterium acnes in the skin. Br J Dermatol. 2014 Dec; 171(6):1358-67.
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Braganhol E, Kukulski F, Lévesque SA, Fausther M, Lavoie EG, Zanotto-Filho A, Bergamin LS, Pelletier J, Bahrami F, Ben Yebdri F, Fonseca Moreira JC, Battastini AM, Sévigny J. Nucleotide receptors control IL-8/CXCL8 and MCP-1/CCL2 secretions as well as proliferation in human glioma cells. Biochim Biophys Acta. 2015 Jan; 1852(1):120-30.
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Kamalakar A, Bendre MS, Washam CL, Fowler TW, Carver A, Dilley JD, Bracey JW, Akel NS, Margulies AG, Skinner RA, Swain FL, Hogue WR, Montgomery CO, Lahiji P, Maher JJ, Leitzel KE, Ali SM, Lipton A, Nicholas RW, Gaddy D, Suva LJ. Circulating interleukin-8 levels explain breast cancer osteolysis in mice and humans. Bone. 2014 Apr; 61:176-85.
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Zabaleta J, Velasco-Gonzalez C, Estrada J, Ravussin E, Pelligrino N, Mohler MC, Larson-Meyer E, Boulares AH, Powell-Young Y, Bennett B, Happel K, Cefalu W, Scribner R, Tseng TS, Sothern M. Inverse correlation of serum inflammatory markers with metabolic parameters in healthy, Black and White prepubertal youth. Int J Obes (Lond). 2014 Apr; 38(4):563-8.
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Saben J, Zhong Y, Gomez-Acevedo H, Thakali KM, Borengasser SJ, Andres A, Shankar K. Early growth response protein-1 mediates lipotoxicity-associated placental inflammation: role in maternal obesity. Am J Physiol Endocrinol Metab. 2013 Jul 01; 305(1):E1-14.
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Khandpur R, Carmona-Rivera C, Vivekanandan-Giri A, Gizinski A, Yalavarthi S, Knight JS, Friday S, Li S, Patel RM, Subramanian V, Thompson P, Chen P, Fox DA, Pennathur S, Kaplan MJ. NETs are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritis. Sci Transl Med. 2013 Mar 27; 5(178):178ra40.
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