 Interleukin-15
"Interleukin-15" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cytokine that stimulates the proliferation of T-LYMPHOCYTES and shares biological activities with IL-2. IL-15 also can induce proliferation and differentiation of B-LYMPHOCYTES.
| Descriptor ID |
D019409
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| MeSH Number(s) |
D12.644.276.374.465.515 D12.776.467.374.465.515 D23.529.374.465.515
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Interleukin-15".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-15".
This graph shows the total number of publications written about "Interleukin-15" by people in UAMS Profiles by year, and whether "Interleukin-15" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2025 | 2 | 0 | 2 | | 2022 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 | | 2016 | 0 | 1 | 1 | | 2014 | 1 | 0 | 1 | | 2012 | 0 | 1 | 1 | | 2009 | 1 | 0 | 1 | | 2006 | 1 | 0 | 1 | | 2004 | 1 | 0 | 1 |
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Below are the most recent publications written about "Interleukin-15" by people in Profiles over the past ten years.
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Ahmed J, O'Sullivan Coyne G, Rubinstein LV, Shin SJ, Takebe N, Bruns A, Augustine B, Mukherjee J, Ma N, Fino K, Fung KL, Ferry-Galow KV, Johnson BC, Parchment RE, Streicher H, Doroshow JH, Chen AP. Phase 1 study evaluating the safety, preliminary efficacy, and pharmacodynamics of recombinant interleukin-15 in combination with nivolumab and ipilimumab in patients with refractory cancers. J Immunother Cancer. 2025 Dec 21; 13(12).
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Cron KR, Fang P, Pham O, Janes J, Brandenburg J, Lu W, Zhu J, Peterson B, Tribble S, Kehoe H, Makarova A, Iannello A, Chan J, Skoble J, He H, Rae C, Thanos CD, Udyavar AR. ACTM-838, a novel systemically delivered bacterial immunotherapy that enriches in solid tumors and delivers IL-15/IL-15Ra and STING payloads to engage innate and adaptive immunity in the TME and enable a durable anti-tumor immune response. Oncotarget. 2025 Oct 06; 16:721-740.
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Muehling LM, Heymann PW, Carper H, Murphy DD, Rajadhyaksha E, Kennedy J, Early SV, Soto-Quiros M, Avila L, Workman L, Platts-Mills TAE, Woodfolk JA. Cluster analysis of nasal cytokines during rhinovirus infection identifies different immunophenotypes in both children and adults with allergic asthma. Clin Exp Allergy. 2022 10; 52(10):1169-1182.
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Al-Attar A, Presnell SR, Clasey JL, Long DE, Walton RG, Sexton M, Starr ME, Kern PA, Peterson CA, Lutz CT. Human Body Composition and Immunity: Visceral Adipose Tissue Produces IL-15 and Muscle Strength Inversely Correlates with NK Cell Function in Elderly Humans. Front Immunol. 2018; 9:440.
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Mishra A, La Perle K, Kwiatkowski S, Sullivan LA, Sams GH, Johns J, Curphey DP, Wen J, McConnell K, Qi J, Wong H, Russo G, Zhang J, Marcucci G, Bradner JE, Porcu P, Caligiuri MA. Mechanism, Consequences, and Therapeutic Targeting of Abnormal IL15 Signaling in Cutaneous T-cell Lymphoma. Cancer Discov. 2016 09; 6(9):986-1005.
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