 Homeodomain Proteins
"Homeodomain Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins encoded by homeobox genes (GENES, HOMEOBOX) that exhibit structural similarity to certain prokaryotic and eukaryotic DNA-binding proteins. Homeodomain proteins are involved in the control of gene expression during morphogenesis and development (GENE EXPRESSION REGULATION, DEVELOPMENTAL).
| Descriptor ID |
D018398
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| MeSH Number(s) |
D12.776.260.400
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| Concept/Terms |
Homeodomain Proteins- Homeodomain Proteins
- Proteins, Homeodomain
- Homeobox Proteins
- Proteins, Homeobox
- Homeotic Proteins
- Proteins, Homeotic
- Homeoproteins
- Homeo Domain Proteins
- Proteins, Homeo Domain
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Below are MeSH descriptors whose meaning is more general than "Homeodomain Proteins".
Below are MeSH descriptors whose meaning is more specific than "Homeodomain Proteins".
This graph shows the total number of publications written about "Homeodomain Proteins" by people in UAMS Profiles by year, and whether "Homeodomain Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2025 | 0 | 1 | 1 | | 2024 | 1 | 1 | 2 | | 2023 | 0 | 1 | 1 | | 2022 | 0 | 3 | 3 | | 2021 | 2 | 0 | 2 | | 2020 | 0 | 1 | 1 | | 2019 | 1 | 1 | 2 | | 2018 | 1 | 2 | 3 | | 2017 | 0 | 1 | 1 | | 2015 | 2 | 0 | 2 | | 2014 | 2 | 0 | 2 | | 2013 | 3 | 1 | 4 | | 2012 | 1 | 2 | 3 | | 2011 | 4 | 3 | 7 | | 2010 | 0 | 6 | 6 | | 2008 | 0 | 1 | 1 | | 2006 | 1 | 0 | 1 | | 2005 | 1 | 2 | 3 | | 2004 | 0 | 3 | 3 | | 2003 | 1 | 1 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Homeodomain Proteins" by people in Profiles over the past ten years.
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Ahn JH, Guo Y, Lyons H, Mackintosh SG, Lau BK, Edmondson RD, Byrum SD, Storey AJ, Tackett AJ, Cai L, Sabari BR, Wang GG. The phenylalanine-and-glycine repeats of NUP98 oncofusions form condensates that selectively partition transcriptional coactivators. Mol Cell. 2025 Feb 20; 85(4):708-725.e9.
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Mercado MAB, Li Q, Quick CM, Kim Y, Palmer R, Huang L, Li LX. BHLHE40 drives protective polyfunctional CD4 T cell differentiation in the female reproductive tract against Chlamydia. PLoS Pathog. 2024 Jan; 20(1):e1011983.
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Shah UA, Moshier E, Derkach A, Huang Y, Mailankody S, Tan CR, Maclachlan K, Hultcrantz M, Korde N, Hassoun H, Thibaud S, Sanchez L, Rodriguez C, Richard S, Richter J, Rossi A, Cho HJ, Lesokhin A, Chari A, Usmani SZ, Jagannath S, Parekh S, Gallagher EJ. Prevalence and impact of diabetes on survival of patients with multiple myeloma in different racial groups. Blood Adv. 2024 01 09; 8(1):236-247.
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O'Neal KA, Zeltner SL, Foscue CL, Stumhofer JS. Bhlhe40 limits early IL-10 production from CD4+ T cells during Plasmodium yoelii 17X infection. Infect Immun. 2023 11 16; 91(11):e0036723.
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Atkinson EG, Adaway M, Horan DJ, Korff C, Klunk A, Orr AL, Ratz K, Bellido T, Plotkin LI, Robling AG, Bidwell JP. Conditional Loss of Nmp4 in Mesenchymal Stem Progenitor Cells Enhances PTH-Induced Bone Formation. J Bone Miner Res. 2023 01; 38(1):70-85.
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Geng L, Li Q, Jiao L, Xiang Y, Deng Q, Zhou DX, Zhao Y. WOX11 and CRL1 act synergistically to promote crown root development by maintaining cytokinin homeostasis in rice. New Phytol. 2023 01; 237(1):204-216.
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Ponte F, Kim HN, Warren A, Iyer S, Han L, Mannen E, Gomez-Acevedo H, Nookaew I, Almeida M, Manolagas SC. Mmp13 deletion in mesenchymal cells increases bone mass and may attenuate the cortical bone loss caused by estrogen deficiency. Sci Rep. 2022 06 17; 12(1):10257.
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Ghosh RN, Guglani L, Westbrook AL, Mao CY, Bai S, Keens TG, Kasi AS. Impaired ventilation during 6-min?walk test in congenital central hypoventilation syndrome. Pediatr Pulmonol. 2022 07; 57(7):1660-1667.
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Ahn JH, Davis ES, Daugird TA, Zhao S, Quiroga IY, Uryu H, Li J, Storey AJ, Tsai YH, Keeley DP, Mackintosh SG, Edmondson RD, Byrum SD, Cai L, Tackett AJ, Zheng D, Legant WR, Phanstiel DH, Wang GG. Phase separation drives aberrant chromatin looping and cancer development. Nature. 2021 07; 595(7868):591-595.
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Kunadirek P, Ariyachet C, Sriphoosanaphan S, Pinjaroen N, Sirichindakul P, Nookaew I, Chuaypen N, Tangkijvanich P. Identification of BHLHE40 expression in peripheral blood mononuclear cells as a novel biomarker for diagnosis and prognosis of hepatocellular carcinoma. Sci Rep. 2021 05 27; 11(1):11201.
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Ponte F, Kim HN, Iyer S, Han L, Almeida M, Manolagas SC. Cxcl12 Deletion in Mesenchymal Cells Increases Bone Turnover and Attenuates the Loss of Cortical Bone Caused by Estrogen Deficiency in Mice. J Bone Miner Res. 2020 08; 35(8):1441-1451.
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Yang F, Shao C, Wei K, Jing X, Qin Z, Shi Y, Shu Y, Shen H. miR-942 promotes tumor migration, invasion, and angiogenesis by regulating EMT via BARX2 in non-small-cell lung cancer. J Cell Physiol. 2019 12; 234(12):23596-23607.
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Iacobucci I, Wen J, Meggendorfer M, Choi JK, Shi L, Pounds SB, Carmichael CL, Masih KE, Morris SM, Lindsley RC, Janke LJ, Alexander TB, Song G, Qu C, Li Y, Payne-Turner D, Tomizawa D, Kiyokawa N, Valentine M, Valentine V, Basso G, Locatelli F, Enemark EJ, Kham SKY, Yeoh AEJ, Ma X, Zhou X, Sioson E, Rusch M, Ries RE, Stieglitz E, Hunger SP, Wei AH, To LB, Lewis ID, D'Andrea RJ, Kile BT, Brown AL, Scott HS, Hahn CN, Marlton P, Pei D, Cheng C, Loh ML, Ebert BL, Meshinchi S, Haferlach T, Mullighan CG. Genomic subtyping and therapeutic targeting of acute erythroleukemia. Nat Genet. 2019 04; 51(4):694-704.
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Howe LJ, Richardson TG, Arathimos R, Alvizi L, Passos-Bueno MR, Stanier P, Nohr E, Ludwig KU, Mangold E, Knapp M, Stergiakouli E, Pourcain BS, Smith GD, Sandy J, Relton CL, Lewis SJ, Hemani G, Sharp GC. Evidence for DNA methylation mediating genetic liability to non-syndromic cleft lip/palate. Epigenomics. 2019 02; 11(2):133-145.
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Poston TB, O'Connell CM, Girardi J, Sullivan JE, Nagarajan UM, Marinov A, Scurlock AM, Darville T. T Cell-Independent Gamma Interferon and B Cells Cooperate To Prevent Mortality Associated with Disseminated Chlamydia muridarum Genital Tract Infection. Infect Immun. 2018 07; 86(7).
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Xiong J, Almeida M, O'Brien CA. The YAP/TAZ transcriptional co-activators have opposing effects at different stages of osteoblast differentiation. Bone. 2018 07; 112:1-9.
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Hughes MW, Jiang TX, Plikus MV, Guerrero-Juarez CF, Lin CH, Schafer C, Maxson R, Widelitz RB, Chuong CM. Msx2 Supports Epidermal Competency?during Wound-Induced Hair?Follicle Neogenesis. J Invest Dermatol. 2018 09; 138(9):2041-2050.
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Shpyleva S, Dreval K, de Conti A, Kindrat I, Melnyk S, Yan J, Chen T, Beland FA, Pogribny IP. Editor's Highlight: Organ-Specific Epigenetic Changes Induced by the Nongenotoxic Liver Carcinogen Methapyrilene in Fischer 344 Rats. Toxicol Sci. 2017 03 01; 156(1):190-198.
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Tas E, Sebastian J, Madan-Khetarpal S, Sweet P, Yatsenko AN, Pollock N, Rajkovic A, Schneck FX, Yatsenko SA, Witchel SF. Familial deletion of the HOXA gene cluster associated with Hand-Foot-Genital syndrome and phenotypic variability. Am J Med Genet A. 2017 Jan; 173(1):221-224.
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Richards EJ, Permuth-Wey J, Li Y, Chen YA, Coppola D, Reid BM, Lin HY, Teer JK, Berchuck A, Birrer MJ, Lawrenson K, Monteiro AN, Schildkraut JM, Goode EL, Gayther SA, Sellers TA, Cheng JQ. A functional variant in HOXA11-AS, a novel long non-coding RNA, inhibits the oncogenic phenotype of epithelial ovarian cancer. Oncotarget. 2015 Oct 27; 6(33):34745-57.
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Tanaka AJ, Cho MT, Millan F, Juusola J, Retterer K, Joshi C, Niyazov D, Garnica A, Gratz E, Deardorff M, Wilkins A, Ortiz-Gonzalez X, Mathews K, Panzer K, Brilstra E, van Gassen KL, Volker-Touw CM, van Binsbergen E, Sobreira N, Hamosh A, McKnight D, Monaghan KG, Chung WK. Mutations in SPATA5 Are Associated with Microcephaly, Intellectual Disability, Seizures, and Hearing Loss. Am J Hum Genet. 2015 Sep 03; 97(3):457-64.
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