 Glycolysis
"Glycolysis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A metabolic process that converts GLUCOSE into two molecules of PYRUVIC ACID through a series of enzymatic reactions. Energy generated by this process is conserved in two molecules of ATP. Glycolysis is the universal catabolic pathway for glucose, free glucose, or glucose derived from complex CARBOHYDRATES, such as GLYCOGEN and STARCH.
| Descriptor ID |
D006019
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| MeSH Number(s) |
G02.111.087.160.750 G02.149.115.160.750 G03.495.256.750 G03.495.335.436 G03.495.553.360
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| Concept/Terms |
Embden-Meyerhof Pathway- Embden-Meyerhof Pathway
- Embden Meyerhof Pathway
- Embden-Meyerhof Pathways
- Pathway, Embden-Meyerhof
- Pathways, Embden-Meyerhof
- Embden-Meyerhof-Parnas Pathway
- Embden Meyerhof Parnas Pathway
- Pathway, Embden-Meyerhof-Parnas
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Below are MeSH descriptors whose meaning is more general than "Glycolysis".
Below are MeSH descriptors whose meaning is more specific than "Glycolysis".
This graph shows the total number of publications written about "Glycolysis" by people in UAMS Profiles by year, and whether "Glycolysis" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2025 | 1 | 0 | 1 | | 2023 | 2 | 0 | 2 | | 2022 | 0 | 2 | 2 | | 2021 | 1 | 4 | 5 | | 2020 | 1 | 1 | 2 | | 2019 | 2 | 0 | 2 | | 2018 | 0 | 4 | 4 | | 2017 | 3 | 3 | 6 | | 2016 | 1 | 2 | 3 | | 2015 | 0 | 1 | 1 | | 2014 | 1 | 1 | 2 | | 2013 | 3 | 1 | 4 | | 2012 | 0 | 2 | 2 | | 2011 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2006 | 1 | 0 | 1 | | 2005 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2002 | 1 | 0 | 1 | | 2000 | 0 | 1 | 1 | | 1999 | 0 | 2 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Glycolysis" by people in Profiles over the past ten years.
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Pi H, Fu Q, Liu J, Zhou H, Wang Y. Excessive apoptosis, glycolysis, and abnormal levels of gluconeogenase in rheumatoid arthritis involves in the dysregulation of glucose metabolism: an animal model study. Autoimmunity. 2025 Dec; 58(1):2499730.
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Theriault JE, Shaffer C, Dienel GA, Sander CY, Hooker JM, Dickerson BC, Barrett LF, Quigley KS. A functional account of stimulation-based aerobic glycolysis and its role in interpreting BOLD signal intensity increases in neuroimaging experiments. Neurosci Biobehav Rev. 2023 10; 153:105373.
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DiNuzzo M, Dienel GA, Behar KL, Petroff OA, Benveniste H, Hyder F, Giove F, Michaeli S, Mangia S, Herculano-Houzel S, Rothman DL. Neurovascular coupling is optimized to compensate for the increase in proton production from nonoxidative glycolysis and glycogenolysis during brain activation and maintain homeostasis of pH, pCO2, and pO2. J Neurochem. 2024 05; 168(5):632-662.
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Cheng Y, Sun F, Thornton K, Jing X, Dong J, Yun G, Pisano M, Zhan F, Kim SH, Katzenellenbogen JA, Katzenellenbogen BS, Hari P, Janz S. FOXM1 regulates glycolysis and energy production in multiple myeloma. Oncogene. 2022 08; 41(32):3899-3911.
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Gumus R, Capik O, Gundogdu B, Tatar A, Altinkaynak K, Ozdemir Tozlu O, Karatas OF. Low vitamin D and high cholesterol facilitate oral carcinogenesis in 4NQO-induced rat models via regulating glycolysis. Oral Dis. 2023 Apr; 29(3):978-989.
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Cha Y, Kim T, Jeon J, Jang Y, Kim PB, Lopes C, Leblanc P, Cohen BM, Kim KS. SIRT2 regulates mitochondrial dynamics and reprogramming via MEK1-ERK-DRP1 and AKT1-DRP1 axes. Cell Rep. 2021 12 28; 37(13):110155.
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McDonald JT, Enguita FJ, Taylor D, Griffin RJ, Priebe W, Emmett MR, Sajadi MM, Harris AD, Clement J, Dybas JM, Aykin-Burns N, Guarnieri JW, Singh LN, Grabham P, Baylin SB, Yousey A, Pearson AN, Corry PM, Saravia-Butler A, Aunins TR, Sharma S, Nagpal P, Meydan C, Foox J, Mozsary C, Cerqueira B, Zaksas V, Singh U, Wurtele ES, Costes SV, Davanzo GG, Galeano D, Paccanaro A, Meinig SL, Hagan RS, Bowman NM, Wolfgang MC, Altinok S, Sapoval N, Treangen TJ, Moraes-Vieira PM, Vanderburg C, Wallace DC, Schisler JC, Mason CE, Chatterjee A, Meller R, Beheshti A. Role of miR-2392 in driving SARS-CoV-2 infection. Cell Rep. 2021 10 19; 37(3):109839.
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Xu C, Tsai YH, Galbo PM, Gong W, Storey AJ, Xu Y, Byrum SD, Xu L, Whang YE, Parker JS, Mackintosh SG, Edmondson RD, Tackett AJ, Huang J, Zheng D, Earp HS, Wang GG, Cai L. Cistrome analysis of YY1 uncovers a regulatory axis of YY1:BRD2/4-PFKP during tumorigenesis of advanced prostate cancer. Nucleic Acids Res. 2021 05 21; 49(9):4971-4988.
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Verma H, Cholia RP, Kaur S, Dhiman M, Mantha AK. A short review on cross-link between pyruvate kinase (PKM2) and Glioblastoma Multiforme. Metab Brain Dis. 2021 06; 36(5):751-765.
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Soeters PB, Shenkin A, Sobotka L, Soeters MR, de Leeuw PW, Wolfe RR. The anabolic role of the Warburg, Cori-cycle and Crabtree effects in health and disease. Clin Nutr. 2021 05; 40(5):2988-2998.
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Harada K, Patnana M, Wang X, Iwatsuki M, Murphy MAB, Zhao M, Das P, Minsky BD, Weston B, Lee JH, Bhutani MS, Estrella JS, Shanbhag N, Ikoma N, Badgwell BD, Ajani JA. Low metabolic activity in primary gastric adenocarcinoma is associated with resistance to chemoradiation and the presence of signet ring cells. Surg Today. 2020 Oct; 50(10):1223-1231.
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Englund DA, Murach KA, Dungan CM, Figueiredo VC, Vechetti IJ, Dupont-Versteegden EE, McCarthy JJ, Peterson CA. Depletion of resident muscle stem cells negatively impacts running volume, physical function, and muscle fiber hypertrophy in response to lifelong physical activity. Am J Physiol Cell Physiol. 2020 06 01; 318(6):C1178-C1188.
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Newhardt MF, Batushansky A, Matsuzaki S, Young ZT, West M, Chin NC, Szweda LI, Kinter M, Humphries KM. Enhancing cardiac glycolysis causes an increase in PDK4 content in response to short-term high-fat diet. J Biol Chem. 2019 11 08; 294(45):16831-16845.
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Dienel GA, Rothman DL. Glycogenolysis in Cerebral Cortex During Sensory Stimulation, Acute Hypoglycemia, and Exercise: Impact on Astrocytic Energetics, Aerobic Glycolysis, and Astrocyte-Neuron Interactions. Adv Neurobiol. 2019; 23:209-267.
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Sedgeman LR, Beysen C, Allen RM, Ramirez Solano MA, Turner SM, Vickers KC. Intestinal bile acid sequestration improves glucose control by stimulating hepatic miR-182-5p in type 2 diabetes. Am J Physiol Gastrointest Liver Physiol. 2018 11 01; 315(5):G810-G823.
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Dienel GA. Metabolomic Assays of Postmortem Brain Extracts: Pitfalls in Extrapolation of Concentrations of Glucose and Amino Acids to Metabolic Dysregulation In Vivo in Neurological Diseases. Neurochem Res. 2019 Oct; 44(10):2239-2260.
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Carlson GM, Dienel GA, Colbran RJ. Introduction to the Thematic Minireview Series: Brain glycogen metabolism. J Biol Chem. 2018 05 11; 293(19):7087-7088.
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Huang L, Nazarova EV, Tan S, Liu Y, Russell DG. Growth of Mycobacterium tuberculosis in vivo segregates with host macrophage metabolism and ontogeny. J Exp Med. 2018 04 02; 215(4):1135-1152.
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Bockus LB, Matsuzaki S, Vadvalkar SS, Young ZT, Giorgione JR, Newhardt MF, Kinter M, Humphries KM. Cardiac Insulin Signaling Regulates Glycolysis Through Phosphofructokinase 2 Content and Activity. J Am Heart Assoc. 2017 Dec 04; 6(12).
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Sonntag KC, Ryu WI, Amirault KM, Healy RA, Siegel AJ, McPhie DL, Forester B, Cohen BM. Late-onset Alzheimer's disease is associated with inherent changes in bioenergetics profiles. Sci Rep. 2017 10 25; 7(1):14038.
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Alhallak K, Jenkins SV, Lee DE, Greene NP, Quinn KP, Griffin RJ, Dings RPM, Rajaram N. Optical imaging of radiation-induced metabolic changes in radiation-sensitive and resistant cancer cells. J Biomed Opt. 2017 06 01; 22(6):60502.
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Kalantari F, Wang J. Attenuation correction in 4D-PET using a single-phase attenuation map and rigidity-adaptive deformable registration. Med Phys. 2017 Feb; 44(2):522-532.
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Dienel GA. Lack of appropriate stoichiometry: Strong evidence against an energetically important astrocyte-neuron lactate shuttle in brain. J Neurosci Res. 2017 11; 95(11):2103-2125.
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Gu Z, Xia J, Xu H, Frech I, Tricot G, Zhan F. NEK2 Promotes Aerobic Glycolysis in Multiple Myeloma Through Regulating Splicing of Pyruvate Kinase. J Hematol Oncol. 2017 01 13; 10(1):17.
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Schibler J, Tomanek-Chalkley AM, Reedy JL, Zhan F, Spitz DR, Schultz MK, Goel A. Mitochondrial-Targeted Decyl-Triphenylphosphonium Enhances 2-Deoxy-D-Glucose Mediated Oxidative Stress and Clonogenic Killing of Multiple Myeloma Cells. PLoS One. 2016; 11(11):e0167323.
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McDonald JE, Kessler MM, Gardner MW, Buros AF, Ntambi JA, Waheed S, van Rhee F, Zangari M, Heuck CJ, Petty N, Schinke C, Thanendrarajan S, Mitchell A, Hoering A, Barlogie B, Morgan GJ, Davies FE. Assessment of Total Lesion Glycolysis by 18F FDG PET/CT Significantly Improves Prognostic Value of GEP and ISS in Myeloma. Clin Cancer Res. 2017 04 15; 23(8):1981-1987.
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Dienel GA, Cruz NF. Aerobic glycolysis during brain activation: adrenergic regulation and influence of norepinephrine on astrocytic metabolism. J Neurochem. 2016 07; 138(1):14-52.
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