 Oxidation-Reduction
"Oxidation-Reduction" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471).
| Descriptor ID |
D010084
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| MeSH Number(s) |
G02.149.767.650 G02.842.750.650 G03.495.335.531
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Oxidation-Reduction".
Below are MeSH descriptors whose meaning is more specific than "Oxidation-Reduction".
This graph shows the total number of publications written about "Oxidation-Reduction" by people in UAMS Profiles by year, and whether "Oxidation-Reduction" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2025 | 0 | 1 | 1 | | 2024 | 2 | 4 | 6 | | 2023 | 0 | 4 | 4 | | 2022 | 0 | 3 | 3 | | 2021 | 0 | 4 | 4 | | 2020 | 1 | 5 | 6 | | 2019 | 0 | 2 | 2 | | 2018 | 0 | 6 | 6 | | 2017 | 0 | 9 | 9 | | 2016 | 0 | 8 | 8 | | 2015 | 0 | 3 | 3 | | 2014 | 0 | 5 | 5 | | 2013 | 1 | 12 | 13 | | 2012 | 0 | 7 | 7 | | 2011 | 0 | 6 | 6 | | 2010 | 0 | 11 | 11 | | 2009 | 0 | 8 | 8 | | 2008 | 0 | 9 | 9 | | 2007 | 1 | 6 | 7 | | 2006 | 0 | 7 | 7 | | 2005 | 0 | 7 | 7 | | 2004 | 1 | 8 | 9 | | 2003 | 0 | 5 | 5 | | 2002 | 0 | 8 | 8 | | 2000 | 0 | 5 | 5 | | 1999 | 0 | 1 | 1 | | 1998 | 0 | 2 | 2 | | 1994 | 0 | 1 | 1 | | 1993 | 0 | 2 | 2 | | 1992 | 0 | 1 | 1 | | 1991 | 0 | 1 | 1 |
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Below are the most recent publications written about "Oxidation-Reduction" by people in Profiles over the past ten years.
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Margolis LM, Allen JT, Murphy NE, Carrigan CT, Howard EE, Barney DE, Drummer DJ, Michalak J, Ferrando AA, Pasiakos SM, Gwin JA. Carbohydrate supplementation maintains physical performance during short-term energy deficit despite reductions in exogenous glucose oxidation. Am J Physiol Endocrinol Metab. 2025 Feb 01; 328(2):E242-E253.
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Starck CS, Wolfe RR, Moughan PJ. Toward a Dynamic Model of Indispensable Amino Acid Requirements of the Adult Human: A Factorial Estimate of Oxidative Amino Acid Losses. J Nutr. 2025 Jan; 155(1):338-352.
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Najjar RS, Grace WW, Siqueira APS, Setka AM, Lu W, Wang S, Feresin RG. Polyphenols have unique cellular effects that are distinct from antioxidant function in Toll-like receptor 4-mediated inflammation in RAW264.7 macrophage-like cells. Nutr Res. 2024 Dec; 132:136-151.
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Hilgers RHP, Das KC. Redox Regulation of K+ Channel: Role of Thioredoxin. Antioxid Redox Signal. 2024 Nov; 41(13-15):818-844.
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Ippel H, Miller MC, Dings RPM, Ludwig AK, Gabius HJ, Mayo KH. Cysteine Oxidation in Human Galectin-1 Occurs Sequentially via a Folded Intermediate to a Fully Oxidized Unfolded Form. Int J Mol Sci. 2024 Jun 25; 25(13).
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Awala SI, Gwak JH, Kim Y, Jung MY, Dunfield PF, Wagner M, Rhee SK. Nitrous oxide respiration in acidophilic methanotrophs. Nat Commun. 2024 May 18; 15(1):4226.
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Wright T, Turnis ME, Grace CR, Li X, Brakefield LA, Wang YD, Xu H, Kaminska E, Climer LK, Mukiza TO, Chang CL, Moldoveanu T, Opferman JT. Anti-apoptotic MCL-1 promotes long-chain fatty acid oxidation through interaction with ACSL1. Mol Cell. 2024 Apr 04; 84(7):1338-1353.e8.
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Yiew NKH, Vazquez JH, Martino MR, Kennon-McGill S, Price JR, Allard FD, Yee EU, Layman AJ, James LP, McCommis KS, Finck BN, McGill MR. Hepatic pyruvate and alanine metabolism are critical and complementary for maintenance of antioxidant capacity and resistance to oxidative insult. Mol Metab. 2023 Nov; 77:101808.
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Derry PJ, Liopo AV, Mouli K, McHugh EA, Vo ATT, McKelvey A, Suva LJ, Wu G, Gao Y, Olson KR, Tour JM, Kent TA. Oxidation of Hydrogen Sulfide to Polysulfide and Thiosulfate by a Carbon Nanozyme: Therapeutic Implications with an Emphasis on Down Syndrome. Adv Mater. 2024 Mar; 36(10):e2211241.
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Warren A, Porter RM, Reyes-Castro O, Ali MM, Marques-Carvalho A, Kim HN, Gatrell LB, Schipani E, Nookaew I, O'Brien CA, Morello R, Almeida M. The NAD salvage pathway in mesenchymal cells is indispensable for skeletal development in mice. Nat Commun. 2023 06 17; 14(1):3616.
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Zhou S, Guo F, Chao CY, Yoon S, Alvarez SL, Shrestha S, Flynn JH, Usenko S, Sheesley RJ, Griffin RJ. Marine Submicron Aerosols from the Gulf of Mexico: Polluted and Acidic with Rapid Production of Sulfate and Organosulfates. Environ Sci Technol. 2023 04 04; 57(13):5149-5159.
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Najjar RS, Wong BJ, Feresin RG. Tissue Derivation and Biological Sex Uniquely Mediate Endothelial Cell Protein Expression, Redox Status, and Nitric Oxide Synthesis. Cells. 2022 12 26; 12(1).
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Najjar RS, Knapp D, Wanders D, Feresin RG. Raspberry and blackberry act in a synergistic manner to improve cardiac redox proteins and reduce NF-?B and SAPK/JNK in mice fed a high-fat, high-sucrose diet. Nutr Metab Cardiovasc Dis. 2022 07; 32(7):1784-1796.
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Das A, Ash D, Fouda AY, Sudhahar V, Kim YM, Hou Y, Hudson FZ, Stansfield BK, Caldwell RB, McMenamin M, Littlejohn R, Su H, Regan MR, Merrill BJ, Poole LB, Kaplan JH, Fukai T, Ushio-Fukai M. Cysteine oxidation of copper transporter CTR1 drives VEGFR2 signalling and angiogenesis. Nat Cell Biol. 2022 01; 24(1):35-50.
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Ruiz de Azua MJ, Cruz-Carri?n ?, Muguerza B, Arola-Arnal A, Suarez M. Seasonal Consumption of Cherries from Different Origins Affects Metabolic Markers and Gene Expression of Lipogenic Enzymes in Rat Liver: A Preliminary Study. Nutrients. 2021 Oct 18; 13(10).
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Frye RE, Lionnard L, Singh I, Karim MA, Chajra H, Frechet M, Kissa K, Racine V, Ammanamanchi A, McCarty PJ, Delhey L, Tippett M, Rose S, Aouacheria A. Mitochondrial morphology is associated with respiratory chain uncoupling in autism spectrum disorder. Transl Psychiatry. 2021 10 13; 11(1):527.
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Barbosa P, Melnyk S, Bennuri SC, Delhey L, Reis A, Moura GR, B?rsheim E, Rose S, Carvalho E. Redox Imbalance and Methylation Disturbances in Early Childhood Obesity. Oxid Med Cell Longev. 2021; 2021:2207125.
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Ono-Moore KD, Olfert IM, Rutkowsky JM, Chintapalli SV, Willis BJ, Blackburn ML, Williams DK, O'Reilly J, Tolentino T, Lloyd KCK, Adams SH. Metabolic physiology and skeletal muscle phenotypes in male and female myoglobin knockout mice. Am J Physiol Endocrinol Metab. 2021 07 01; 321(1):E63-E79.
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Edwards AD, Marecki JC, Byrd AK, Gao J, Raney KD. G-Quadruplex loops regulate PARP-1 enzymatic activation. Nucleic Acids Res. 2021 01 11; 49(1):416-431.
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Simmen FA, Alhallak I, Simmen RCM. Malic enzyme 1 (ME1) in the biology of cancer: it is not just intermediary metabolism. J Mol Endocrinol. 2020 11; 65(4):R77-R90.
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Dienel GA, Rothman DL. Reevaluation of Astrocyte-Neuron Energy Metabolism with Astrocyte Volume Fraction Correction: Impact on Cellular Glucose Oxidation Rates, Glutamate-Glutamine Cycle Energetics, Glycogen Levels and Utilization Rates vs. Exercising Muscle, and Na+/K+ Pumping Rates. Neurochem Res. 2020 Nov; 45(11):2607-2630.
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Gu C, Brereton N, Schweitzer A, Cotter M, Duan D, B?rsheim E, Wolfe RR, Pham LV, Polotsky VY, Jun JC. Metabolic Effects of Late Dinner in Healthy Volunteers-A Randomized Crossover Clinical Trial. J Clin Endocrinol Metab. 2020 08 01; 105(8).
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Zheng ZZ, Zheng LW, Xu MN, Tan E, Hutchins DA, Deng W, Zhang Y, Shi D, Dai M, Kao SJ. Substrate regulation leads to differential responses of microbial ammonia-oxidizing communities to ocean warming. Nat Commun. 2020 07 14; 11(1):3511.
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Tandon I, Kolenc OI, Cross D, Vargas I, Johns S, Quinn KP, Balachandran K. Label-free metabolic biomarkers for assessing valve interstitial cell calcific progression. Sci Rep. 2020 06 25; 10(1):10317.
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Tascioglu Aliyev A, LoBianco F, Krager KJ, Aykin-Burns N. Assessment of Cellular Oxidation using a Subcellular Compartment-Specific Redox-Sensitive Green Fluorescent Protein. J Vis Exp. 2020 06 18; (160).
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McElroy T, Brown T, Kiffer F, Wang J, Byrum SD, Oberley-Deegan RE, Allen AR. Assessing the Effects of Redox Modifier MnTnBuOE-2-PyP 5+ on Cognition and Hippocampal Physiology Following Doxorubicin, Cyclophosphamide, and Paclitaxel Treatment. Int J Mol Sci. 2020 Mar 09; 21(5).
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Krantz GP, Lucas K, Wunderlich EL, Hoang LT, Avci R, Siuzdak G, Fields MW. Bulk phase resource ratio alters carbon steel corrosion rates and endogenously produced extracellular electron transfer mediators in a sulfate-reducing biofilm. Biofouling. 2019 07; 35(6):669-683.
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Barone R, Rizzo R, Tabb? G, Malaguarnera M, Frye RE, Bastin J. Nuclear Peroxisome Proliferator-Activated Receptors (PPARs) as Therapeutic Targets of Resveratrol for Autism Spectrum Disorder. Int J Mol Sci. 2019 Apr 16; 20(8).
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McCoin CS, Gillingham MB, Knotts TA, Vockley J, Ono-Moore KD, Blackburn ML, Norman JE, Adams SH. Blood cytokine patterns suggest a modest inflammation phenotype in subjects with long-chain fatty acid oxidation disorders. Physiol Rep. 2019 03; 7(6):e14037.
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Solverson PM, Rumpler WV, Leger JL, Redan BW, Ferruzzi MG, Baer DJ, Castonguay TW, Novotny JA. Blackberry Feeding Increases Fat Oxidation and Improves Insulin Sensitivity in Overweight and Obese Males. Nutrients. 2018 Aug 09; 10(8).
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Khan FZ, Hutcheson JA, Hunter CJ, Powless AJ, Benson D, Fritsch I, Muldoon TJ. Redox-Magnetohydrodynamically Controlled Fluid Flow with Poly(3,4-ethylenedioxythiophene) Coupled to an Epitaxial Light Sheet Confocal Microscope for Image Cytometry Applications. Anal Chem. 2018 07 03; 90(13):7862-7870.
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Lee DE, Alhallak K, Jenkins SV, Vargas I, Greene NP, Quinn KP, Griffin RJ, Dings RPM, Rajaram N. A Radiosensitizing Inhibitor of HIF-1 alters the Optical Redox State of Human Lung Cancer Cells In Vitro. Sci Rep. 2018 06 11; 8(1):8815.
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Ambrogini E, Que X, Wang S, Yamaguchi F, Weinstein RS, Tsimikas S, Manolagas SC, Witztum JL, Jilka RL. Oxidation-specific epitopes restrain bone formation. Nat Commun. 2018 06 06; 9(1):2193.
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Prakash D, Walters KA, Martinie RJ, McCarver AC, Kumar AK, Lessner DJ, Krebs C, Golbeck JH, Ferry JG. Toward a mechanistic and physiological understanding of a ferredoxin:disulfide reductase from the domains Archaea and Bacteria. J Biol Chem. 2018 06 15; 293(24):9198-9209.
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Schafer C, Young ZT, Makarewich CA, Elnwasany A, Kinter C, Kinter M, Szweda LI. Coenzyme A-mediated degradation of pyruvate dehydrogenase kinase 4 promotes cardiac metabolic flexibility after high-fat feeding in mice. J Biol Chem. 2018 05 04; 293(18):6915-6924.
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Huang L, Nazarova EV, Tan S, Liu Y, Russell DG. Growth of Mycobacterium tuberculosis in vivo segregates with host macrophage metabolism and ontogeny. J Exp Med. 2018 04 02; 215(4):1135-1152.
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Das KC, Kundumani-Sridharan V, Subramani J. Role of Thioredoxin in Age-Related Hypertension. Curr Hypertens Rep. 2018 02 14; 20(1):6.
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Olson KR, Gao Y, Arif F, Arora K, Patel S, DeLeon ER, Sutton TR, Feelisch M, Cortese-Krott MM, Straub KD. Metabolism of hydrogen sulfide (H2S) and Production of Reactive Sulfur Species (RSS) by superoxide dismutase. Redox Biol. 2018 05; 15:74-85.
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Sonntag KC, Ryu WI, Amirault KM, Healy RA, Siegel AJ, McPhie DL, Forester B, Cohen BM. Late-onset Alzheimer's disease is associated with inherent changes in bioenergetics profiles. Sci Rep. 2017 10 25; 7(1):14038.
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Bhattacharyya S, Ali M, Smith WH, Minkler PE, Stoll MS, Hoppel CL, Adams SH. Anesthesia and bariatric surgery gut preparation alter plasma acylcarnitines reflective of mitochondrial fat and branched-chain amino acid oxidation. Am J Physiol Endocrinol Metab. 2017 12 01; 313(6):E690-E698.
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Frye RE, Rose S, Wynne R, Bennuri SC, Blossom S, Gilbert KM, Heilbrun L, Palmer RF. Oxidative Stress Challenge Uncovers Trichloroacetaldehyde Hydrate-Induced Mitoplasticity in Autistic and Control Lymphoblastoid Cell Lines. Sci Rep. 2017 06 30; 7(1):4478.
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Hutchins DA, Fu F. Microorganisms and ocean global change. Nat Microbiol. 2017 May 25; 2:17058.
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Petibone DM, Mustafa T, Bourdo SE, Lafont A, Ding W, Karmakar A, Nima ZA, Watanabe F, Casciano D, Morris SM, Dobrovolsky VN, Biris AS. p53-competent cells and p53-deficient cells display different susceptibility to oxygen functionalized graphene cytotoxicity and genotoxicity. J Appl Toxicol. 2017 Nov; 37(11):1333-1345.
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Dang NL, Hughes TB, Miller GP, Swamidass SJ. Computational Approach to Structural Alerts: Furans, Phenols, Nitroaromatics, and Thiophenes. Chem Res Toxicol. 2017 04 17; 30(4):1046-1059.
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Chouinard VA, Kim SY, Valeri L, Yuksel C, Ryan KP, Chouinard G, Cohen BM, Du F, ?ng?r D. Brain bioenergetics and redox state measured by 31P magnetic resonance spectroscopy in unaffected siblings of patients with psychotic disorders. Schizophr Res. 2017 09; 187:11-16.
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Wang Y, Safirstein R, Velazquez H, Guo XJ, Hollander L, Chang J, Chen TM, Mu JJ, Desir GV. Extracellular renalase protects cells and organs by outside-in signalling. J Cell Mol Med. 2017 07; 21(7):1260-1265.
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Hilgers RH, Kundumani-Sridharan V, Subramani J, Chen LC, Cuello LG, Rusch NJ, Das KC. Thioredoxin reverses age-related hypertension by chronically improving vascular redox and restoring eNOS function. Sci Transl Med. 2017 02 08; 9(376).
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Sharma M, Afolayan AJ. Redox Signaling and Persistent Pulmonary Hypertension of the Newborn. Adv Exp Med Biol. 2017; 967:277-287.
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Zhang J, Light AR, Hoppel CL, Campbell C, Chandler CJ, Burnett DJ, Souza EC, Casazza GA, Hughen RW, Keim NL, Newman JW, Hunter GR, Fernandez JR, Garvey WT, Harper ME, Fiehn O, Adams SH. Acylcarnitines as markers of exercise-associated fuel partitioning, xenometabolism, and potential signals to muscle afferent neurons. Exp Physiol. 2017 01 01; 102(1):48-69.
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Aguer C, Piccolo BD, Fiehn O, Adams SH, Harper ME. A novel amino acid and metabolomics signature in mice overexpressing muscle uncoupling protein 3. FASEB J. 2017 02; 31(2):814-827.
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Kim SY, Cohen BM, Chen X, Lukas SE, Shinn AK, Yuksel AC, Li T, Du F, ?ng?r D. Redox Dysregulation in Schizophrenia Revealed by in vivo NAD+/NADH Measurement. Schizophr Bull. 2017 01; 43(1):197-204.
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Earthman CP, Wolfe RR, Heymsfield SB. Dudrick Research Symposium 2015-Lean Tissue and Protein in Health and Disease. JPEN J Parenter Enteral Nutr. 2017 02; 41(2):226-237.
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Chondronikola M, Volpi E, B?rsheim E, Porter C, Saraf MK, Annamalai P, Yfanti C, Chao T, Wong D, Shinoda K, Labbe SM, Hurren NM, Cesani F, Kajimura S, Sidossis LS. Brown Adipose Tissue Activation Is Linked to Distinct Systemic Effects on Lipid Metabolism in Humans. Cell Metab. 2016 06 14; 23(6):1200-1206.
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Heard ME, Melnyk SB, Simmen FA, Yang Y, Pabona JM, Simmen RC. High-Fat Diet Promotion of Endometriosis in an Immunocompetent Mouse Model is Associated With Altered Peripheral and Ectopic Lesion Redox and Inflammatory Status. Endocrinology. 2016 07; 157(7):2870-82.
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Pencharz PB, Elango R, Wolfe RR. Recent developments in understanding protein needs - How much and what kind should we eat? Appl Physiol Nutr Metab. 2016 May; 41(5):577-80.
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Trexler ET, Smith-Ryan AE, Wingfield HL, Blue MN, Roelofs EJ, Hirsch KR. Dietary macronutrient distribution influences postexercise substrate utilization in women: a cross-sectional evaluation of metabolic flexibility. J Sports Med Phys Fitness. 2017 May; 57(5):580-588.
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McCoin CS, Piccolo BD, Knotts TA, Matern D, Vockley J, Gillingham MB, Adams SH. Unique plasma metabolomic signatures of individuals with inherited disorders of long-chain fatty acid oxidation. J Inherit Metab Dis. 2016 05; 39(3):399-408.
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