 Sirtuin 3
"Sirtuin 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sirtuin family member found primarily in MITOCHONDRIA. It is a multifunctional enzyme that contains a NAD-dependent deacetylase activity that is specific for HISTONES and a mono-ADP-ribosyltransferase activity.
| Descriptor ID |
D056566
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| MeSH Number(s) |
D08.811.277.087.520.200.650.600 D08.811.913.400.725.115.961.600 D12.776.476.900.600 D12.776.575.875
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| Concept/Terms |
Sirtuin 3- Sirtuin 3
- Silent Mating Type Information Regulation 2 Homolog 3
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Below are MeSH descriptors whose meaning is more general than "Sirtuin 3".
Below are MeSH descriptors whose meaning is more specific than "Sirtuin 3".
This graph shows the total number of publications written about "Sirtuin 3" by people in UAMS Profiles by year, and whether "Sirtuin 3" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 1 | 0 | 1 | | 2023 | 1 | 0 | 1 | | 2022 | 0 | 1 | 1 | | 2021 | 1 | 0 | 1 | | 2013 | 0 | 1 | 1 | | 2011 | 2 | 0 | 2 | | 2010 | 1 | 0 | 1 | | 2008 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Sirtuin 3" by people in Profiles over the past ten years.
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Richardson KK, Adam GO, Ling W, Warren A, Marques-Carvalho A, Thostenson JD, Krager K, Aykin-Burns N, Byrum SD, Almeida M, Kim HN. Mitochondrial protein deacetylation by SIRT3 in osteoclasts promotes bone resorption with aging in female mice. Mol Metab. 2024 Oct; 88:102012.
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Allen AR, Jones A', LoBianco FV, Krager KJ, Aykin-Burns N. Effect of Sirt3 on hippocampal MnSOD activity, mitochondrial function, physiology, and cognition in an aged murine model. Behav Brain Res. 2023 04 27; 444:114335.
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Richardson KK, Ling W, Krager K, Fu Q, Byrum SD, Pathak R, Aykin-Burns N, Kim HN. Ionizing Radiation Activates Mitochondrial Function in Osteoclasts and Causes Bone Loss in Young Adult Male Mice. Int J Mol Sci. 2022 Jan 08; 23(2).
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Ling W, Krager K, Richardson KK, Warren AD, Ponte F, Aykin-Burns N, Manolagas SC, Almeida M, Kim HN. Mitochondrial Sirt3 contributes to the bone loss caused by aging or estrogen deficiency. JCI Insight. 2021 05 24; 6(10).
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