A family of proteinase-activated receptors that are specific for THROMBIN. They are found primarily on PLATELETS and on ENDOTHELIAL CELLS. Activation of thrombin receptors occurs through the proteolytic action of THROMBIN, which cleaves the N-terminal peptide from the receptor to reveal a new N-terminal peptide that is a cryptic ligand for the receptor. The receptors signal through HETEROTRIMERIC GTP-BINDING PROTEINS. Small synthetic peptides that contain the unmasked N-terminal peptide sequence can also activate the receptor in the absence of proteolytic activity.

Descriptor ID	D018179
MeSH Number(s)	D12.776.395.550.625.800 D12.776.543.550.625.800 D12.776.543.750.100.875 D12.776.543.750.750.850 D12.776.543.750.792.500
Concept/Terms	Receptors, Thrombin Receptors, Thrombin Thrombin Receptors Thrombin Receptor Receptor, Thrombin Thrombin Receptor Activating Peptides Thrombin Receptor Activating Peptides Thrombin Receptor Activator Peptide TRAP Peptide Peptide, TRAP Thrombin Receptor Activating Peptide Ligand

Below are MeSH descriptors whose meaning is more general than "Receptors, Thrombin".

Below are MeSH descriptors whose meaning is related to "Receptors, Thrombin".

Below are MeSH descriptors whose meaning is more specific than "Receptors, Thrombin".