 Immunity, Innate
"Immunity, Innate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The capacity of a normal organism to remain unaffected by microorganisms and their toxins. It results from the presence of naturally occurring ANTI-INFECTIVE AGENTS, constitutional factors such as BODY TEMPERATURE and immediate acting immune cells such as NATURAL KILLER CELLS.
| Descriptor ID |
D007113
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| MeSH Number(s) |
G12.450.564
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| Concept/Terms |
Immunity, Innate- Immunity, Innate
- Innate Immunity
- Immunity, Non-Specific
- Immunity, Non Specific
- Non-Specific Immunity
- Immunity, Native
- Native Immunity
- Immunity, Natural
- Natural Immunity
Innate Immune Response- Innate Immune Response
- Immune Response, Innate
- Immune Responses, Innate
- Innate Immune Responses
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Below are MeSH descriptors whose meaning is more general than "Immunity, Innate".
Below are MeSH descriptors whose meaning is more specific than "Immunity, Innate".
This graph shows the total number of publications written about "Immunity, Innate" by people in UAMS Profiles by year, and whether "Immunity, Innate" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2025 | 0 | 1 | 1 | | 2024 | 3 | 3 | 6 | | 2022 | 0 | 1 | 1 | | 2021 | 1 | 1 | 2 | | 2020 | 4 | 1 | 5 | | 2019 | 0 | 1 | 1 | | 2018 | 3 | 1 | 4 | | 2017 | 1 | 1 | 2 | | 2016 | 2 | 0 | 2 | | 2015 | 1 | 2 | 3 | | 2014 | 3 | 1 | 4 | | 2013 | 0 | 2 | 2 | | 2012 | 3 | 2 | 5 | | 2011 | 0 | 3 | 3 | | 2010 | 4 | 3 | 7 | | 2008 | 1 | 0 | 1 | | 2007 | 0 | 1 | 1 | | 2006 | 0 | 2 | 2 | | 1999 | 0 | 2 | 2 |
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Below are the most recent publications written about "Immunity, Innate" by people in Profiles over the past ten years.
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Hurst JH, Mohan AA, Dalapati T, George IA, Aquino JN, Lugo DJ, Pfeiffer TS, Rodriguez J, Rotta AT, Turner NA, Burke TW, McClain MT, Henao R, DeMarco CT, Louzao R, Denny TN, Walsh KM, Xu Z, Mejias A, Ramilo O, Woods CW, Kelly MS. Age-associated differences in mucosal and systemic host responses to SARS-CoV-2 infection. Nat Commun. 2025 Mar 10; 16(1):2383.
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Oh C, Spears TJ, Aachoui Y. Inflammasome-mediated pyroptosis in defense against pathogenic bacteria. Immunol Rev. 2025 Jan; 329(1):e13408.
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Liu Z, Kong N, Zhang Y, Zheng Y, Yang C, Fu Q, Zhang Z, Li F, Liu R, Wang L, Song L. The phytoplankton community affects the energy metabolism and immunomodulation strategy of oyster during breeding seasons. Fish Shellfish Immunol. 2024 Oct; 153:109819.
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Venugopal G, Pechous RD. Yersinia pestis and pneumonic plague: Insight into how a lethal pathogen interfaces with innate immune populations in the lung to cause severe disease. Cell Immunol. 2024 Sep-Oct; 403-404:104856.
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Pechous RD, Malaviarachchi PA, Banerjee SK, Byrum SD, Alkam DH, Ghaffarieh A, Kurten RC, Kennedy JL, Zhang X. An ex vivo human precision-cut lung slice platform provides insight into SARS-CoV-2 pathogenesis and antiviral drug efficacy. J Virol. 2024 Jul 23; 98(7):e0079424.
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Ghimire L, Paudel S, Le J, Jin L, Cai S, Bhattarai D, Jeyaseelan S. NLRP6 negatively regulates host defense against polymicrobial sepsis. Front Immunol. 2024; 15:1248907.
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Gurung M, Schlegel BT, Rajasundaram D, Fox R, Bode L, Yao T, Lindemann SR, LeRoith T, Read QD, Simecka C, Carroll L, Andres A, Yeruva L. Microbiota from human infants consuming secretors or non-secretors mothers' milk impacts the gut and immune system in mice. mSystems. 2024 Apr 16; 9(4):e0029424.
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Kieber-Emmons T. Broad Based Immunity? Monoclon Antib Immunodiagn Immunother. 2022 10; 41(5):229-230.
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Feng X, Lawrence MG, Payne SC, Mattos J, Etter E, Negri JA, Murphy D, Kennedy JL, Steinke JW, Borish L. Lower viral loads in subjects with rhinovirus-challenged allergy despite reduced innate immunity. Ann Allergy Asthma Immunol. 2022 04; 128(4):414-422.e2.
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Khare VM, Saxena VK, Pasternak MA, Nyinawabera A, Singh KB, Ashby CR, Tiwari AK, Tang Y. The expression profiles of chemokines, innate immune and apoptotic genes in tumors caused by Rous Sarcoma Virus (RSV-A) in chickens. Genes Immun. 2022 02; 23(1):12-22.
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Mercado MAB, Du W, Malaviarachchi PA, Gann JI, Li LX. Innate IFN-? Is Essential for Systemic Chlamydia muridarum Control in Mice, While CD4 T Cell-Dependent IFN-? Production Is Highly Redundant in the Female Reproductive Tract. Infect Immun. 2021 02 16; 89(3).
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Stuart JD, Salinas E, Grakoui A. Immune system control of hepatitis C virus infection. Curr Opin Virol. 2021 02; 46:36-44.
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Osterman MT, Gordon IO, Davis EM, Ciorba M, Glover SC, Abraham B, Khan F, Guo X, Yee EU, Allard FD, Claggett B, Shen B, Liu JJ. Mucosal Biomarker of Innate Immune Activation Predicts Response to Vedolizumab in Crohn's Disease. Inflamm Bowel Dis. 2020 09 18; 26(10):1554-1561.
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Oh C, Verma A, Aachoui Y. Caspase-11 Non-canonical Inflammasomes in the Lung. Front Immunol. 2020; 11:1895.
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Kar UK, Joosten LAB. Training the trainable cells of the immune system and beyond. Nat Immunol. 2020 02; 21(2):115-119.
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Coleman CM. Determining How Coronaviruses Overcome the Interferon and Innate Immune Response. Methods Mol Biol. 2020; 2203:223-229.
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Svahn SL, Guti?rrez S, Ulleryd MA, Nookaew I, Osla V, Beckman F, Nilsson S, Karlsson A, Jansson JO, Johansson ME. Dietary Polyunsaturated Fatty Acids Promote Neutrophil Accumulation in the Spleen by Altering Chemotaxis and Delaying Cell Death. Infect Immun. 2019 08; 87(8).
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Giebel AM, Hu S, Rajaram K, Finethy R, Toh E, Brothwell JA, Morrison SG, Suchland RJ, Stein BD, Coers J, Morrison RP, Nelson DE. Genetic Screen in Chlamydia muridarum Reveals Role for an Interferon-Induced Host Cell Death Program in Antimicrobial Inclusion Rupture. mBio. 2019 04 09; 10(2).
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Zimmer A, Bagchi AK, Vinayak K, Bello-Klein A, Singal PK. Innate immune response in the pathogenesis of heart failure in survivors of myocardial infarction. Am J Physiol Heart Circ Physiol. 2019 03 01; 316(3):H435-H445.
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Yang FM, Zuo Y, Zhou W, Xia C, Hahm B, Sullivan M, Cheng J, Chang HM, Yeh ET. sNASP inhibits TLR signaling to regulate immune response in sepsis. J Clin Invest. 2018 06 01; 128(6):2459-2472.
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Bhattarai D, Worku T, Dad R, Rehman ZU, Gong X, Zhang S. Mechanism of pattern recognition receptors (PRRs) and host pathogen interplay in bovine mastitis. Microb Pathog. 2018 Jul; 120:64-70.
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Gao X, Cao Q, Cheng Y, Zhao D, Wang Z, Yang H, Wu Q, You L, Wang Y, Lin Y, Li X, Wang Y, Bian JS, Sun D, Kong L, Birnbaumer L, Yang Y. Chronic stress promotes colitis by disturbing the gut microbiota and triggering immune system response. Proc Natl Acad Sci U S A. 2018 03 27; 115(13):E2960-E2969.
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Lao Y, Yang K, Wang Z, Sun X, Zou Q, Yu X, Cheng J, Tong X, Yeh ETH, Yang J, Yi J. DeSUMOylation of MKK7 kinase by the SUMO2/3 protease SENP3 potentiates lipopolysaccharide-induced inflammatory signaling in macrophages. J Biol Chem. 2018 03 16; 293(11):3965-3980.
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Ayoub KF, Pothineni NVK, Rutland J, Ding Z, Mehta JL. Immunity, Inflammation, and Oxidative Stress in Heart Failure: Emerging Molecular Targets. Cardiovasc Drugs Ther. 2017 Dec; 31(5-6):593-608.
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Pechous RD. With Friends Like These: The Complex Role of Neutrophils in the Progression of Severe Pneumonia. Front Cell Infect Microbiol. 2017; 7:160.
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Karta MR, Rosenthal PS, Beppu A, Vuong CY, Miller M, Das S, Kurten RC, Doherty TA, Broide DH. ?2 integrins rather than ?1 integrins mediate Alternaria-induced group 2 innate lymphoid cell trafficking to the lung. J Allergy Clin Immunol. 2018 01; 141(1):329-338.e12.
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Qiang YW, Ye S, Chen Y, Buros AF, Edmonson R, van Rhee F, Barlogie B, Epstein J, Morgan GJ, Davies FE. MAF protein mediates innate resistance to proteasome inhibition therapy in multiple myeloma. Blood. 2016 12 22; 128(25):2919-2930.
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Cho NE, Bang BR, Gurung P, Li M, Clemens DL, Underhill TM, James LP, Chase JR, Saito T. Retinoid regulation of antiviral innate immunity in hepatocytes. Hepatology. 2016 06; 63(6):1783-95.
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Huang L, Beiting DP, Gebreselassie NG, Gagliardo LF, Ruyechan MC, Lee NA, Lee JJ, Appleton JA. Eosinophils and IL-4 Support Nematode Growth Coincident with an Innate Response to Tissue Injury. PLoS Pathog. 2015 Dec; 11(12):e1005347.
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Panchanathan R, Liu H, Leung YK, Ho SM, Choubey D. Bisphenol A (BPA) stimulates the interferon signaling and activates the inflammasome activity in myeloid cells. Mol Cell Endocrinol. 2015 Nov 05; 415:45-55.
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