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Fen Xia

TitleDepartment Chairperson
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentDepartment Chairs, College of Medicine
Address4130 Shuffield Dr.
Mail Slot # 771
Little Rock AR 72205
Phone501-686-7283
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    Collapse Research 
    Collapse research activities and funding
    P20GM152281     (EOFF, ROBERT L)Mar 5, 2024 - Dec 31, 2028
    NIH
    Center for Molecular Interactions in Cancer (CMIC)
    Role: Co-Investigator
    n/z     (XIA, FEN)Dec 12, 2023 - Dec 11, 2033
    GT Medical Technologies, Inc.
    A Phase 3 Randomized Controlled Trial of Post-Surgical Stereotactic Radiotherapy (SRT)versus Surgically Targeted Radiation Therapy (STaRT) with Gamma Tile for Treatment of Newly Diagnosed Metastatic Brain Tumors.
    Role: Principal Investigator
    P20GM125503     (OBRIEN, CHARLES A)Apr 1, 2023 - Jan 31, 2028
    NIH/Nat. Inst. of General Medical Sciences
    Center for Musculoskeletal Disease Research (CMDR)
    Role: Co-Investigator
    R01CA247947     (XIA, FEN)Apr 1, 2020 - Mar 31, 2026
    NIH
    The novel role of Sirtuin 2 in regulation of transcription-associated DNA damage repair
    Role: Principal Investigator
    R01CA188500     (XIA, FEN)Sep 2, 2014 - Aug 31, 2021
    NIH
    Novel functions of Pyruvate kinase M2 in DNA double-strand break repair
    Role: Principal Investigator
    R01CA188500     (XIA, FEN)Sep 2, 2014 - Aug 31, 2020
    NIH/NCI
    Novel functions of Pyruvate kinase M2 in DNA double-strand break repair
    Role: Principal Investigator
    R01CA163838     (XIA, FEN)Jul 12, 2012 - Apr 30, 2019
    NIH
    GSK3b mediates radiation-induced cytotoxicity in hippocampal neurons
    Role: Principal Investigator
    R01CA163838     (XIA, FEN)Jul 12, 2012 - Apr 30, 2019
    NIH
    GSK3b mediates radiation-induced cytotoxicity in hippocampal neurons
    Role: Principal Investigator
    R01CA118158     (XIA, FEN)Sep 26, 2006 - Oct 31, 2012
    NIH
    The role of BRCA1 in nonhomologous repair of chromosomal double-strand breaks
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Nissen C, Ying J, Kalantari F, Patel M, Prabhu AV, Kesaria A, Kim T, Maraboyina S, Harrell L, Xia F, Lewis GD. A Prospective Study Measuring Resident and Faculty Contour Concordance: A Potential Tool for Quantitative Assessment of Residents' Performance in Contouring and Target Delineation in Radiation Oncology Residency. J Am Coll Radiol. 2024 Mar; 21(3):464-472. PMID: 37844655.
      View in: PubMed
    2. Nissen C, Ying J, Newkirk M, Narayanasamy G, Lewis G, Xia F. An Analysis of Risk Factors for Radiation Necrosis Following Cranial Radiation. Cureus. 2022 Sep; 14(9):e29268. PMID: 36133504.
      View in: PubMed
    3. Shrestha N, Narayanasamy G, Kalantari F, Sabouri P, Xia F, Zhong S. A phantom-based study and clinical implementation of brainlab's treatment planning system for radiosurgical treatments of arteriovenous malformations. Biomed Phys Eng Express. 2022 07 29; 8(5). PMID: 35856850.
      View in: PubMed
    4. Acklin S, Sadhukhan R, Du W, Patra M, Cholia R, Xia F. Nicotinamide riboside alleviates cisplatin-induced peripheral neuropathy via SIRT2 activation. Neurooncol Adv. 2022 Jan-Dec; 4(1):vdac101. PMID: 35875690.
      View in: PubMed
    5. Kesaria AZ, Bimali M, Patel M, Prabhu A, Kesaria S, Xia F. #Brachytherapy: Physicians As Influencers on Instagram. Cureus. 2022 Feb; 14(2):e22524. PMID: 35371782.
      View in: PubMed
    6. Deshazer G, Narayanasamy G, Bimali M, Galhardo E, Kalantari F, Xia F, Pe?agar?cano J, Morrill S. A dosimetric comparative analysis of Brainlab elements and Eclipse RapidArc for spine SBRT treatment planning. Biomed Phys Eng Express. 2022 02 10; 8(2). PMID: 35086071.
      View in: PubMed
    7. Kiss RC, Xia F, Acklin S. Targeting DNA Damage Response and Repair to Enhance Therapeutic Index in Cisplatin-Based Cancer Treatment. Int J Mol Sci. 2021 Jul 30; 22(15). PMID: 34360968.
      View in: PubMed
    8. Zhang M, Acklin S, Gillenwater J, Du W, Patra M, Yu H, Xu B, Yu J, Xia F. SIRT2 promotes murine melanoma progression through natural killer cell inhibition. Sci Rep. 2021 06 21; 11(1):12988. PMID: 34155309.
      View in: PubMed
    9. Prabhu AV, Lee M, Galhardo E, Newkirk M, Rodriguez A, Xia F. Pulsed reduced dose-rate radiotherapy for previously irradiated tumors in the brain and spine. Surg Neurol Int. 2021; 12:280. PMID: 34221611.
      View in: PubMed
    10. Acklin S, Xia F. The Role of Nucleotide Excision Repair in Cisplatin-Induced Peripheral Neuropathy: Mechanism, Prevention, and Treatment. Int J Mol Sci. 2021 Feb 17; 22(4). PMID: 33671279.
      View in: PubMed
    11. Acklin S, Zhang M, Du W, Zhao X, Plotkin M, Chang J, Campisi J, Zhou D, Xia F. Depletion of senescent-like neuronal cells alleviates cisplatin-induced peripheral neuropathy in mice. Sci Rep. 2020 08 25; 10(1):14170. PMID: 32843706.
      View in: PubMed
    12. Patel M, Nowsheen S, Maraboyina S, Xia F. The role of poly(ADP-ribose) polymerase inhibitors in the treatment of cancer and methods to overcome resistance: a review. Cell Biosci. 2020; 10:35. PMID: 32180937.
      View in: PubMed
    13. Zhao X, Du W, Zhang M, Atiq ZO, Xia F. Sirt2-associated transcriptome modifications in cisplatin-induced neuronal injury. BMC Genomics. 2020 Mar 02; 21(1):192. PMID: 32122297.
      View in: PubMed
    14. Miousse IR, Tobacyk J, Quick CM, Jamshidi-Parsian A, Skinner CM, Kore R, Melnyk SB, Kutanzi KR, Xia F, Griffin RJ, Koturbash I. Modulation of dietary methionine intake elicits potent, yet distinct, anticancer effects on primary versus metastatic tumors. Carcinogenesis. 2018 09 21; 39(9):1117-1126. PMID: 29939201.
      View in: PubMed
    15. Yu H, Harrison FE, Xia F. Altered DNA repair; an early pathogenic pathway in Alzheimer's disease and obesity. Sci Rep. 2018 04 04; 8(1):5600. PMID: 29618789.
      View in: PubMed
    16. Zhang X, Rong Y, Morrill S, Fang J, Narayanasamy G, Galhardo E, Maraboyina S, Croft C, Xia F, Penagaricano J. Robust optimization in lung treatment plans accounting for geometric uncertainty. J Appl Clin Med Phys. 2018 May; 19(3):19-26. PMID: 29524301.
      View in: PubMed
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