 DEAD-box RNA Helicases
"DEAD-box RNA Helicases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A large family of RNA helicases that share a common protein motif with the single letter amino acid sequence D-E-A-D (Asp-Glu-Ala-Asp). In addition to RNA helicase activity, members of the DEAD-box family participate in other aspects of RNA metabolism and regulation of RNA function.
| Descriptor ID |
D053487
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| MeSH Number(s) |
D08.811.913.696.445.735.720.249
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| Concept/Terms |
DEAD-box RNA Helicases- DEAD-box RNA Helicases
- DEAD box RNA Helicases
- Helicases, DEAD-box RNA
- RNA Helicases, DEAD-box
DEAD Box Helicase p68- DEAD Box Helicase p68
- p68 RNA Helicase
- Helicase, p68 RNA
- RNA Helicase, p68
- p68 DEAD Box Protein
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Below are MeSH descriptors whose meaning is more general than "DEAD-box RNA Helicases".
Below are MeSH descriptors whose meaning is more specific than "DEAD-box RNA Helicases".
This graph shows the total number of publications written about "DEAD-box RNA Helicases" by people in UAMS Profiles by year, and whether "DEAD-box RNA Helicases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 0 | 1 | 1 | | 2023 | 0 | 3 | 3 | | 2022 | 0 | 1 | 1 | | 2021 | 1 | 1 | 2 | | 2020 | 1 | 1 | 2 | | 2019 | 1 | 0 | 1 | | 2017 | 1 | 1 | 2 | | 2016 | 0 | 1 | 1 | | 2015 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2012 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2008 | 1 | 1 | 2 | | 2007 | 1 | 0 | 1 |
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Below are the most recent publications written about "DEAD-box RNA Helicases" by people in Profiles over the past ten years.
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Abla O, Ries RE, Triche T, Gerbing RB, Hirsch B, Raimondi S, Cooper T, Farrar JE, Buteyn N, Harmon LM, Wen H, Deshpande AJ, Kolb EA, Gamis AS, Aplenc R, Alonzo T, Meshinchi S. Structural variants involving MLLT10 fusion are associated with adverse outcomes in pediatric acute myeloid leukemia. Blood Adv. 2024 04 23; 8(8):2005-2017.
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Naik U, Shah M, Sandberg DI, Samant R, Roy A, Bhattacharjee MB. Histopathologic "Evolution" in Pediatric Primary Intracranial High-Grade Sarcoma - a Key that Unlocked the Correct Diagnosis. Ann Clin Lab Sci. 2023 Jul; 53(4):661-666.
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Li J, Zhou Y, Zhao W, Liu J, Ullah R, Fang P, Fang L, Xiao S. Porcine reproductive and respiratory syndrome virus degrades DDX10 via SQSTM1/p62-dependent selective autophagy to antagonize its antiviral activity. Autophagy. 2023 08; 19(8):2257-2274.
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Ricarte-Filho JC, Casado-Medrano V, Reichenberger E, Spangler Z, Scheerer M, Isaza A, Baran J, Patel T, MacFarland SP, Brodeur GM, Stewart DR, Baloch Z, Bauer AJ, Wasserman JD, Franco AT. DICER1 RNase IIIb domain mutations trigger widespread miRNA dysregulation and MAPK activation in pediatric thyroid cancer. Front Endocrinol (Lausanne). 2023; 14:1083382.
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Baran JA, Halada S, Bauer AJ, Ricarte-Filho JC, Isaza A, Surrey LF, McGrath C, Bhatti T, Jalaly J, Mostoufi-Moab S, Franco AT, Adzick NS, Kazahaya K, Cahill AM, Baloch Z. Indeterminate Thyroid Fine-Needle Aspirations in Pediatrics: Exploring Clinicopathologic Features and Utility of Molecular Profiling. Horm Res Paediatr. 2022; 95(5):430-441.
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Marecki JC, Belachew B, Gao J, Raney KD. RNA helicases required for viral propagation in humans. Enzymes. 2021; 50:335-367.
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Gao J, Gao Z, Putnam AA, Byrd AK, Venus SL, Marecki JC, Edwards AD, Lowe HM, Jankowsky E, Raney KD. G-quadruplex DNA inhibits unwinding activity but promotes liquid-liquid phase separation by the DEAD-box helicase Ded1p. Chem Commun (Camb). 2021 Jul 27; 57(60):7445-7448.
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Dungan CM, Valentino T, Vechetti IJ, Zdunek CJ, Murphy MP, Lin AL, McCarthy JJ, Peterson CA. Exercise-mediated alteration of hippocampal Dicer mRNA and miRNAs is associated with lower BACE1 gene expression and A?1-42 in female 3xTg-AD mice. J Neurophysiol. 2020 12 01; 124(6):1571-1577.
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Liu D, Zeng X, Li X, Cui C, Hou R, Guo Z, Mehta JL, Wang X. Advances in the molecular mechanisms of NLRP3 inflammasome activators and inactivators. Biochem Pharmacol. 2020 05; 175:113863.
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Gao J, Byrd AK, Zybailov BL, Marecki JC, Guderyon MJ, Edwards AD, Chib S, West KL, Waldrip ZJ, Mackintosh SG, Gao Z, Putnam AA, Jankowsky E, Raney KD. DEAD-box RNA helicases Dbp2, Ded1 and Mss116 bind to G-quadruplex nucleic acids and destabilize G-quadruplex RNA. Chem Commun (Camb). 2019 Apr 11; 55(31):4467-4470.
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Pierce JM, LaCroix P, Heym K, Bowman WP, Margraf L, Iglesias J, Ray A. Pleuropulmonary Blastoma: A Single-center Case Series of 6 Patients. J Pediatr Hematol Oncol. 2017 11; 39(8):e419-e422.
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Piatek MJ, Henderson V, Fearn A, Chaudhry B, Werner A. Ectopically expressed Slc34a2a sense-antisense transcripts cause a cerebellar phenotype in zebrafish embryos depending on RNA complementarity and Dicer. PLoS One. 2017; 12(5):e0178219.
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Luizon MR, Eckalbar WL, Wang Y, Jones SL, Smith RP, Laurance M, Lin L, Gallins PJ, Etheridge AS, Wright F, Zhou Y, Molony C, Innocenti F, Yee SW, Giacomini KM, Ahituv N. Genomic Characterization of Metformin Hepatic Response. PLoS Genet. 2016 Nov; 12(11):e1006449.
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Blair LP, Liu Z, Labitigan RL, Wu L, Zheng D, Xia Z, Pearson EL, Nazeer FI, Cao J, Lang SM, Rines RJ, Mackintosh SG, Moore CL, Li W, Tian B, Tackett AJ, Yan Q. KDM5 lysine demethylases are involved in maintenance of 3'UTR length. Sci Adv. 2016 Nov; 2(11):e1501662.
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Epling LB, Grace CR, Lowe BR, Partridge JF, Enemark EJ. Cancer-associated mutants of RNA helicase DDX3X are defective in RNA-stimulated ATP hydrolysis. J Mol Biol. 2015 May 08; 427(9):1779-1796.
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