 Muscle Fibers, Skeletal
"Muscle Fibers, Skeletal" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Large, multinucleate single cells, either cylindrical or prismatic in shape, that form the basic unit of SKELETAL MUSCLE. They consist of MYOFIBRILS enclosed within and attached to the SARCOLEMMA. They are derived from the fusion of skeletal myoblasts (MYOBLASTS, SKELETAL) into a syncytium, followed by differentiation.
| Descriptor ID |
D018485
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| MeSH Number(s) |
A10.690.552.500.500 A11.620.249
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| Concept/Terms |
Muscle Fibers, Skeletal- Muscle Fibers, Skeletal
- Fiber, Skeletal Muscle
- Fibers, Skeletal Muscle
- Muscle Fiber, Skeletal
- Skeletal Muscle Fiber
- Myotubes
- Myotube
- Skeletal Myocytes
- Myocytes, Skeletal
- Myocyte, Skeletal
- Skeletal Myocyte
- Skeletal Muscle Fibers
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Below are MeSH descriptors whose meaning is more general than "Muscle Fibers, Skeletal".
Below are MeSH descriptors whose meaning is more specific than "Muscle Fibers, Skeletal".
This graph shows the total number of publications written about "Muscle Fibers, Skeletal" by people in UAMS Profiles by year, and whether "Muscle Fibers, Skeletal" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2024 | 0 | 1 | 1 | | 2023 | 0 | 1 | 1 | | 2022 | 3 | 2 | 5 | | 2021 | 1 | 0 | 1 | | 2020 | 2 | 1 | 3 | | 2019 | 6 | 2 | 8 | | 2018 | 2 | 1 | 3 | | 2017 | 2 | 0 | 2 | | 2016 | 2 | 4 | 6 | | 2015 | 2 | 0 | 2 | | 2014 | 2 | 0 | 2 | | 2013 | 4 | 0 | 4 | | 2012 | 4 | 0 | 4 | | 2011 | 3 | 0 | 3 | | 2009 | 0 | 1 | 1 | | 2007 | 1 | 0 | 1 | | 2004 | 0 | 3 | 3 | | 2001 | 0 | 1 | 1 | | 2000 | 1 | 0 | 1 | | 1995 | 0 | 1 | 1 |
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Below are the most recent publications written about "Muscle Fibers, Skeletal" by people in Profiles over the past ten years.
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Mehanna LE, Osborne AR, Peterson CA, Berron BJ. Spontaneous Alignment of Myotubes Through Myogenic Progenitor Cell Migration. Tissue Eng Part A. 2024 Mar; 30(5-6):192-203.
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Nolt GL, Keeble AR, Wen Y, Strong AC, Thomas NT, Valentino TR, Brightwell CR, Murach KA, Patrizia S, Weinstabl H, Gollner A, McCarthy JJ, Fry CS, Franti M, Filareto A, Peterson CA, Dungan CM. Inhibition of p53-MDM2 binding reduces senescent cell abundance and improves the adaptive responses of skeletal muscle from aged mice. Geroscience. 2024 04; 46(2):2153-2176.
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Saini SK, P?rez-Cremades D, Cheng HS, Kosmac K, Peterson CA, Li L, Tian L, Dong G, Wu KK, Bouverat B, Wohlgemuth SE, Ryan T, Sufit RL, Ferrucci L, McDermott MM, Leeuwenburgh C, Feinberg MW. Dysregulated Genes, MicroRNAs, Biological Pathways, and Gastrocnemius Muscle Fiber Types Associated With Progression of Peripheral Artery Disease: A Preliminary Analysis. J Am Heart Assoc. 2022 11; 11(21):e023085.
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Avci R, Wickens JD, Sangi M, Athavale ON, Di Natale MR, Furness JB, Du P, Cheng LK. A Computational Model of Biophysical Properties of the Rat Stomach Informed by Comprehensive Analysis of Muscle Anatomy. Annu Int Conf IEEE Eng Med Biol Soc. 2022 07; 2022:4954-4957.
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Long DE, Peck BD, Lavin KM, Dungan CM, Kosmac K, Tuggle SC, Bamman MM, Kern PA, Peterson CA. Skeletal muscle properties show collagen organization and immune cell content are associated with resistance exercise response heterogeneity in older persons. J Appl Physiol (1985). 2022 06 01; 132(6):1432-1447.
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Peck BD, Murach KA, Walton RG, Simmons AJ, Long DE, Kosmac K, Dungan CM, Kern PA, Bamman MM, Peterson CA. A muscle cell-macrophage axis involving matrix metalloproteinase 14 facilitates extracellular matrix remodeling with mechanical loading. FASEB J. 2022 02; 36(2):e22155.
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Viggars MR, Wen Y, Peterson CA, Jarvis JC. Automated cross-sectional analysis of trained, severely atrophied, and recovering rat skeletal muscles using MyoVision 2.0. J Appl Physiol (1985). 2022 03 01; 132(3):593-610.
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Murach KA, Fry CS, Dupont-Versteegden EE, McCarthy JJ, Peterson CA. Fusion and beyond: Satellite cell contributions to loading-induced skeletal muscle adaptation. FASEB J. 2021 10; 35(10):e21893.
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Murach KA, Vechetti IJ, Van Pelt DW, Crow SE, Dungan CM, Figueiredo VC, Kosmac K, Fu X, Richards CI, Fry CS, McCarthy JJ, Peterson CA. Fusion-Independent Satellite Cell Communication to Muscle Fibers During Load-Induced Hypertrophy. Function (Oxf). 2020; 1(1):zqaa009.
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Blackburn ML, Ono-Moore KD, Sobhi HF, Adams SH. Carnitine palmitoyltransferase 2 knockout potentiates palmitate-induced insulin resistance in C2C12 myotubes. Am J Physiol Endocrinol Metab. 2020 08 01; 319(2):E265-E275.
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Englund DA, Murach KA, Dungan CM, Figueiredo VC, Vechetti IJ, Dupont-Versteegden EE, McCarthy JJ, Peterson CA. Depletion of resident muscle stem cells negatively impacts running volume, physical function, and muscle fiber hypertrophy in response to lifelong physical activity. Am J Physiol Cell Physiol. 2020 06 01; 318(6):C1178-C1188.
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Dungan CM, Peck BD, Walton RG, Huang Z, Bamman MM, Kern PA, Peterson CA. In vivo analysis of ?H2AX+ cells in skeletal muscle from aged and obese humans. FASEB J. 2020 05; 34(5):7018-7035.
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Murach KA, Dungan CM, Kosmac K, Voigt TB, Tourville TW, Miller MS, Bamman MM, Peterson CA, Toth MJ. Fiber typing human skeletal muscle with fluorescent immunohistochemistry. J Appl Physiol (1985). 2019 12 01; 127(6):1632-1639.
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Murach KA, Dungan CM, Peterson CA, McCarthy JJ. Response. Exerc Sport Sci Rev. 2019 10; 47(4):260.
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Moro T, Brightwell CR, Phalen DE, McKenna CF, Lane SJ, Porter C, Volpi E, Rasmussen BB, Fry CS. Low skeletal muscle capillarization limits muscle adaptation to resistance exercise training in older adults. Exp Gerontol. 2019 11; 127:110723.
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Englund DA, Peck BD, Murach KA, Neal AC, Caldwell HA, McCarthy JJ, Peterson CA, Dupont-Versteegden EE. Resident muscle stem cells are not required for testosterone-induced skeletal muscle hypertrophy. Am J Physiol Cell Physiol. 2019 10 01; 317(4):C719-C724.
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Rose S, Carvalho E, Diaz EC, Cotter M, Bennuri SC, Azhar G, Frye RE, Adams SH, B?rsheim E. A comparative study of mitochondrial respiration in circulating blood cells and skeletal muscle fibers in women. Am J Physiol Endocrinol Metab. 2019 09 01; 317(3):E503-E512.
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Murach KA, Dungan CM, Peterson CA, McCarthy JJ. Muscle Fiber Splitting Is a Physiological Response to Extreme Loading in Animals. Exerc Sport Sci Rev. 2019 04; 47(2):108-115.
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Dungan CM, Murach KA, Frick KK, Jones SR, Crow SE, Englund DA, Vechetti IJ, Figueiredo VC, Levitan BM, Satin J, McCarthy JJ, Peterson CA. Elevated myonuclear density during skeletal muscle hypertrophy in response to training is reversed during detraining. Am J Physiol Cell Physiol. 2019 05 01; 316(5):C649-C654.
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Walton RG, Kosmac K, Mula J, Fry CS, Peck BD, Groshong JS, Finlin BS, Zhu B, Kern PA, Peterson CA. Human skeletal muscle macrophages increase following cycle training and are associated with adaptations that may facilitate growth. Sci Rep. 2019 01 30; 9(1):969.
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Schnell DM, Walton RG, Vekaria HJ, Sullivan PG, Bollinger LM, Peterson CA, Thomas DT. Vitamin D produces a perilipin 2-dependent increase in mitochondrial function in C2C12 myotubes. J Nutr Biochem. 2019 03; 65:83-92.
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Harada Y, Gokden M, Masangkay N, Sadjadi R. Clinical Reasoning: Subacute paresis in a 28-year-old man with HIV. Neurology. 2018 02 27; 90(9):432-435.
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Murach KA, Fry CS, Kirby TJ, Jackson JR, Lee JD, White SH, Dupont-Versteegden EE, McCarthy JJ, Peterson CA. Starring or Supporting Role? Satellite Cells and Skeletal Muscle Fiber Size Regulation. Physiology (Bethesda). 2018 Jan 01; 33(1):26-38.
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Stuart CA, Lee ML, South MA, Howell MEA, Stone MH. Muscle hypertrophy in prediabetic men after 16 wk of resistance training. J Appl Physiol (1985). 2017 Oct 01; 123(4):894-901.
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McCarthy JJ, Dupont-Versteegden EE, Fry CS, Murach KA, Peterson CA. Methodological issues limit interpretation of negative effects of satellite cell depletion on adult muscle hypertrophy. Development. 2017 04 15; 144(8):1363-1365.
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Fry CS, Kirby TJ, Kosmac K, McCarthy JJ, Peterson CA. Myogenic Progenitor Cells Control Extracellular Matrix Production by Fibroblasts during Skeletal Muscle Hypertrophy. Cell Stem Cell. 2017 01 05; 20(1):56-69.
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South MA, Layne AS, Stuart CA, Triplett NT, Ramsey M, Howell ME, Sands WA, Mizuguchi S, Hornsby WG, Kavanaugh AA, Stone MH. Effects of Short-Term Free-Weight and Semiblock Periodization Resistance Training on Metabolic Syndrome. J Strength Cond Res. 2016 Oct; 30(10):2682-96.
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White SH, McDermott MM, Sufit RL, Kosmac K, Bugg AW, Gonzalez-Freire M, Ferrucci L, Tian L, Zhao L, Gao Y, Kibbe MR, Criqui MH, Leeuwenburgh C, Peterson CA. Walking performance is positively correlated to calf muscle fiber size in peripheral artery disease subjects, but fibers show aberrant mitophagy: an observational study. J Transl Med. 2016 09 29; 14(1):284.
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Soni NK, Ross AB, Scheers N, Savolainen OI, Nookaew I, Gabrielsson BG, Sandberg AS. Eicosapentaenoic and Docosahexaenoic Acid-Enriched High Fat Diet Delays Skeletal Muscle Degradation in Mice. Nutrients. 2016 Sep 03; 8(9).
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Phillips C, Salehi A. A Special Regenerative Rehabilitation and Genomics Letter: Is There a "Hope" Molecule? Phys Ther. 2016 Apr; 96(4):581-3.
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Kirby TJ, Patel RM, McClintock TS, Dupont-Versteegden EE, Peterson CA, McCarthy JJ. Myonuclear transcription is responsive to mechanical load and DNA content but uncoupled from cell size during hypertrophy. Mol Biol Cell. 2016 Mar 01; 27(5):788-98.
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Porter C, Herndon DN, Bhattarai N, Ogunbileje JO, Szczesny B, Szabo C, Toliver-Kinsky T, Sidossis LS. Differential acute and chronic effects of burn trauma on murine skeletal muscle bioenergetics. Burns. 2016 Feb; 42(1):112-122.
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Lee JD, Fry CS, Mula J, Kirby TJ, Jackson JR, Liu F, Yang L, Dupont-Versteegden EE, McCarthy JJ, Peterson CA. Aged Muscle Demonstrates Fiber-Type Adaptations in Response to Mechanical Overload, in the Absence of Myofiber Hypertrophy, Independent of Satellite Cell Abundance. J Gerontol A Biol Sci Med Sci. 2016 Apr; 71(4):461-7.
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McCoin CS, Knotts TA, Ono-Moore KD, Oort PJ, Adams SH. Long-chain acylcarnitines activate cell stress and myokine release in C2C12 myotubes: calcium-dependent and -independent effects. Am J Physiol Endocrinol Metab. 2015 Jun 01; 308(11):E990-E1000.
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