 Septins
"Septins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of GTP-binding proteins that were initially identified in YEASTS where they were shown to initiate the process of septation and bud formation. Septins form into hetero-oligomeric complexes that are comprised of several distinct septin subunits. These complexes can act as cytoskeletal elements that play important roles in CYTOKINESIS, cytoskeletal reorganization, BIOLOGICAL TRANSPORT, and membrane dynamics.
| Descriptor ID |
D058112
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| MeSH Number(s) |
D08.811.277.040.330.300.700 D12.776.157.325.757 D12.776.220.932
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Septins".
Below are MeSH descriptors whose meaning is more specific than "Septins".
This graph shows the total number of publications written about "Septins" by people in UAMS Profiles by year, and whether "Septins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2020 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2011 | 1 | 0 | 1 | | 2006 | 0 | 1 | 1 | | 2004 | 0 | 3 | 3 | | 2002 | 0 | 3 | 3 |
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Below are the most recent publications written about "Septins" by people in Profiles over the past ten years.
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Martinez Barrera S, Byrum S, Mackintosh SG, Kozubowski L. Registered report protocol: Quantitative analysis of septin Cdc10-associated proteome in Cryptococcus neoformans. PLoS One. 2020; 15(12):e0242381.
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Vargas-Mu?iz JM, Renshaw H, Waitt G, Soderblom EJ, Moseley MA, Palmer JM, Juvvadi PR, Keller NP, Steinbach WJ. Caspofungin exposure alters the core septin AspB interactome of Aspergillus fumigatus. Biochem Biophys Res Commun. 2017 04 01; 485(2):221-226.
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Vargas-Mu?iz JM, Juvvadi PR, Steinbach WJ. Forging the ring: from fungal septins' divergent roles in morphology, septation and virulence to factors contributing to their assembly into higher order structures. Microbiology (Reading). 2016 09; 162(9):1527-1534.
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Vargas-Mu?iz JM, Renshaw H, Richards AD, Lamoth F, Soderblom EJ, Moseley MA, Juvvadi PR, Steinbach WJ. The Aspergillus fumigatus septins play pleiotropic roles in septation, conidiation, and cell wall stress, but are dispensable for virulence. Fungal Genet Biol. 2015 Aug; 81:41-51.
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