 Serum Response Factor
"Serum Response Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A MADS domain-containing transcription factor that binds to the SERUM RESPONSE ELEMENT in the promoter-enhancer region of many genes. It is one of the four founder proteins that structurally define the superfamily of MADS DOMAIN PROTEINS.
| Descriptor ID |
D026362
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| MeSH Number(s) |
D12.776.260.400.249.875 D12.776.930.397.875
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| Concept/Terms |
Serum Response Factor- Serum Response Factor
- Response Factor, Serum
- Transcription Factor SRF
- c-fos Serum Response Factor
- c fos Serum Response Factor
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Below are MeSH descriptors whose meaning is more general than "Serum Response Factor".
Below are MeSH descriptors whose meaning is more specific than "Serum Response Factor".
This graph shows the total number of publications written about "Serum Response Factor" by people in UAMS Profiles by year, and whether "Serum Response Factor" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 1 | 0 | 1 | | 2022 | 1 | 0 | 1 | | 2017 | 2 | 0 | 2 | | 2014 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2006 | 1 | 1 | 2 | | 2004 | 1 | 0 | 1 | | 2003 | 1 | 0 | 1 |
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Below are the most recent publications written about "Serum Response Factor" by people in Profiles over the past ten years.
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Patyal P, Zhang X, Verma A, Azhar G, Wei JY. Inhibitors of Rho/MRTF/SRF Transcription Pathway Regulate Mitochondrial Function. Cells. 2024 Feb 24; 13(5).
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Patyal P, Nguyen B, Zhang X, Azhar G, Ameer FS, Verma A, Crane J, Kc G, Che Y, Wei JY. Rho/SRF Inhibitor Modulates Mitochondrial Functions. Int J Mol Sci. 2022 Sep 29; 23(19).
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Zhang X, Azhar G, Wei JY. SIRT2 gene has a classic SRE element, is a downstream target of serum response factor and is likely activated during serum stimulation. PLoS One. 2017; 12(12):e0190011.
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Williams ED, Rogers SC, Zhang X, Azhar G, Wei JY. p49/STRAP, a Serum Response Factor Binding Protein (SRFBP1), Is Involved in the Redistribution of Cytoskeletal F-Actin Proteins during Glucose Deprivation. J Nutr Health Aging. 2017; 21(10):1142-1150.
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Zhang X, Azhar G, Rogers SC, Foster SR, Luo S, Wei JY. Overexpression of p49/STRAP alters cellular cytoskeletal structure and gross anatomy in mice. BMC Cell Biol. 2014 Sep 02; 15:32.
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