 Histone-Lysine N-Methyltransferase
"Histone-Lysine N-Methyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the methylation of the epsilon-amino group of lysine residues in proteins to yield epsilon mono-, di-, and trimethyllysine. EC 2.1.1.43.
| Descriptor ID |
D011495
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| MeSH Number(s) |
D08.811.913.555.500.800.400
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| Concept/Terms |
Histone-Lysine N-Methyltransferase- Histone-Lysine N-Methyltransferase
- Histone Lysine N Methyltransferase
- N-Methyltransferase, Histone-Lysine
- Protein Methylase III
- Histone-Lysine Methyltransferase
- Histone Lysine Methyltransferase
- Methyltransferase, Histone-Lysine
- Protein Lysine Methyltransferase
- Methyltransferase, Protein Lysine
- Protein Methyltransferase III
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Below are MeSH descriptors whose meaning is more general than "Histone-Lysine N-Methyltransferase".
Below are MeSH descriptors whose meaning is more specific than "Histone-Lysine N-Methyltransferase".
This graph shows the total number of publications written about "Histone-Lysine N-Methyltransferase" by people in UAMS Profiles by year, and whether "Histone-Lysine N-Methyltransferase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 1 | 0 | 1 | | 2023 | 0 | 1 | 1 | | 2022 | 1 | 0 | 1 | | 2021 | 0 | 1 | 1 | | 2020 | 1 | 1 | 2 | | 2019 | 0 | 1 | 1 | | 2016 | 3 | 2 | 5 | | 2014 | 3 | 2 | 5 | | 2013 | 0 | 2 | 2 | | 2012 | 1 | 1 | 2 | | 2011 | 1 | 1 | 2 | | 2010 | 5 | 0 | 5 | | 2009 | 2 | 1 | 3 | | 2008 | 4 | 0 | 4 | | 2007 | 0 | 1 | 1 | | 2006 | 2 | 0 | 2 | | 2005 | 1 | 1 | 2 | | 2002 | 0 | 1 | 1 |
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Below are the most recent publications written about "Histone-Lysine N-Methyltransferase" by people in Profiles over the past ten years.
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Leung JW, Miller KM. DOT1L: orchestrating methylation-dependent radiotheRAPy responses via BRCA1. Trends Pharmacol Sci. 2024 Nov; 45(11):955-957.
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Sobh A, Encinas E, Patel A, Surapaneni G, Bonilla E, Kaestner C, Poullard J, Clerio M, Vasan K, Freeman T, Lv D, Dup?r?-Richer D, Riva A, Barwick BG, Zhou D, Boise LH, Mitsiades CS, Kim B, Bennett RL, Chandel NS, Licht JD. NSD2 drives t(4;14) myeloma cell dependence on adenylate kinase 2 by diverting one-carbon metabolism to the epigenome. Blood. 2024 07 18; 144(3):283-295.
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Schuberth K, Ramani PK, Beemarajan E, Veerapandiyan A. Child Neurology: KMT2B-Related Dystonia in a Young Child With Worsening Gait Abnormality. Neurology. 2023 08 15; 101(7):328-332.
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Vinson DA, Stephens KE, O'Meally RN, Bhat S, Dancy BCR, Cole RN, Yegnasubramanian S, Taverna SD. De novo methylation of histone H3K23 by the methyltransferases EHMT1/GLP and EHMT2/G9a. Epigenetics Chromatin. 2022 11 21; 15(1):36.
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Fenu EM, O'Neill SS, Insuasti-Beltran G, Pettenati MJ, Giffen M, Harrison WT. Sudden Unexpected Death in a Child From Acute Myeloid Leukemia. Am J Forensic Med Pathol. 2021 Jun 01; 42(2):174-177.
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Liu X, Zhao Y, Luedke C, Jug R, Yang LH, Lu M, Pan Z, Wang D, Lorsbach R, Shi Y, Knez V, Rehder C, Liang X, Wang E. Infantile leukemia-What factors determine its distinct biological nature? Clinicopathological study of 78 cases. Int J Lab Hematol. 2021 Oct; 43(5):1117-1122.
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El Jamal SM, Salama A, Marcellino BK, Abulsayen HA, Zhou X, Hassan M, Firpo-Betancourt A, Saad AG. Myeloid Sarcoma of the Testis in Children: Clinicopathologic and Immunohistochemical Characteristics With KMT2A (MLL) Gene Rearrangement Correlation. Appl Immunohistochem Mol Morphol. 2020 08; 28(7):501-507.
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Dong C, West KL, Tan XY, Li J, Ishibashi T, Yu CH, Sy SMH, Leung JWC, Huen MSY. Screen identifies DYRK1B network as mediator of transcription repression on damaged chromatin. Proc Natl Acad Sci U S A. 2020 07 21; 117(29):17019-17030.
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Mousavian Z, Nowzari-Dalini A, Rahmatallah Y, Masoudi-Nejad A. Differential network analysis and protein-protein interaction study reveals active protein modules in glucocorticoid resistance for infant acute lymphoblastic leukemia. Mol Med. 2019 08 01; 25(1):36.
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Kim HS, Williamson EA, Nickoloff JA, Hromas RA, Lee SH. Metnase Mediates Loading of Exonuclease 1 onto Single Strand Overhang DNA for End Resection at Stalled Replication Forks. J Biol Chem. 2017 01 27; 292(4):1414-1425.
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Mousavian Z, Nowzari-Dalini A, Stam RW, Rahmatallah Y, Masoudi-Nejad A. Network-based expression analysis reveals key genes related to glucocorticoid resistance in infant acute lymphoblastic leukemia. Cell Oncol (Dordr). 2017 Feb; 40(1):33-45.
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Pawlyn C, Kaiser MF, Heuck C, Melchor L, Wardell CP, Murison A, Chavan SS, Johnson DC, Begum DB, Dahir NM, Proszek PZ, Cairns DA, Boyle EM, Jones JR, Cook G, Drayson MT, Owen RG, Gregory WM, Jackson GH, Barlogie B, Davies FE, Walker BA, Morgan GJ. The Spectrum and Clinical Impact of Epigenetic Modifier Mutations in Myeloma. Clin Cancer Res. 2016 Dec 01; 22(23):5783-5794.
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Wang Q, Trevino LS, Wong RL, Medvedovic M, Chen J, Ho SM, Shen J, Foulds CE, Coarfa C, O'Malley BW, Shilatifard A, Walker CL. Reprogramming of the Epigenome by MLL1 Links Early-Life Environmental Exposures to Prostate Cancer Risk. Mol Endocrinol. 2016 Aug; 30(8):856-71.
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Wu SP, Pfeiffer RM, Ahn IE, Mailankody S, Sonneveld P, van Duin M, Munshi NC, Walker BA, Morgan G, Landgren O. Impact of Genes Highly Correlated with MMSET Myeloma on the Survival of Non-MMSET Myeloma Patients. Clin Cancer Res. 2016 Aug 15; 22(16):4039-44.
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