Cholesterol 7-alpha-Hydroxylase
"Cholesterol 7-alpha-Hydroxylase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A membrane-bound cytochrome P450 enzyme that catalyzes the 7-alpha-hydroxylation of CHOLESTEROL in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP7, converts cholesterol to 7-alpha-hydroxycholesterol which is the first and rate-limiting step in the synthesis of BILE ACIDS.
| Descriptor ID |
D002790
|
| MeSH Number(s) |
D08.244.453.915.200 D08.811.682.690.708.170.915.200 D08.811.682.690.708.783.200 D12.776.422.220.453.915.200
|
| Concept/Terms |
Cholesterol 7-alpha-Hydroxylase- Cholesterol 7-alpha-Hydroxylase
- Cholesterol 7 alpha Hydroxylase
- Cholesterol 7alpha-Hydroxylase
- Cholesterol 7alpha Hydroxylase
- Cholesterol-7-Hydroxylase
- Cholesterol 7 Hydroxylase
- Cytochrome P450 7
- CYP 7A
- CYP7
- CYP7A
- Cytochrome P-450 CYP7
- Cytochrome P 450 CYP7
- Cholesterol 7-alpha-Monooxygenase
- Cholesterol 7 alpha Monooxygenase
- CYP 7
|
Below are MeSH descriptors whose meaning is more general than "Cholesterol 7-alpha-Hydroxylase".
Below are MeSH descriptors whose meaning is more specific than "Cholesterol 7-alpha-Hydroxylase".
This graph shows the total number of publications written about "Cholesterol 7-alpha-Hydroxylase" by people in UAMS Profiles by year, and whether "Cholesterol 7-alpha-Hydroxylase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cholesterol 7-alpha-Hydroxylase" by people in Profiles over the past ten years.
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Mercer KE, Bhattacharyya S, Diaz-Rubio ME, Piccolo BD, Pack LM, Sharma N, Chaudhury M, Cleves MA, Chintapalli SV, Shankar K, Ronis MJJ, Yeruva L. Infant Formula Feeding Increases Hepatic Cholesterol 7a Hydroxylase (CYP7A1) Expression and Fecal Bile Acid Loss in Neonatal Piglets. J Nutr. 2018 05 01; 148(5):702-711.