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Qiang Fu

TitleAssistant Research Professor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentInternal Med, College of Medicine
DivisionInternal Med Endo
Address4301 W. Markham
Mail Slot # 587
Little Rock AR 72205
Phone501-686-6778
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    Collapse Research Funds 
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    R43AI138868     (FU, QIANG)Aug 14, 2018 - Jul 31, 2021
    NIH/Nat. Inst. of Allergy & Infectious Diseases - Pass Through: Innovation Pathways
    Evaluation of IPW-5371, a TGFRI kinase inhibitor, dosed as a single agent or in combination with G-CSF, as a medical countermeasure against the delayed effects of total body irradiation in mice
    Role: Principal Investigator

    W81XWH-15-C-0117     (HAUER-JENSEN, MARTIN)Oct 1, 2015 - Sep 20, 2021
    US Department of Defense - Pass Through: Armed Forces Radiobiology Research Institute
    Advanced Development of Gamma-Tocotrienol as a Radiation Countermeasure
    Role: Co-Investigator

    W81XWH-15-1-0489     (PAWAR, SNEHALATA)Sep 1, 2015 - Aug 31, 2019
    US Department of Defense
    Role of C/EBP delta in IR-induced sepsis
    Role: Co-Investigator

    U19AI067798     (HAUER-JENSEN, MARTIN)Aug 1, 2010 - Jul 31, 2015
    NIH/Nat. Inst. of Allergy & Infectious Diseases - Pass Through: Duke University
    Somatostatin Analogs as Countermeasures Against Intestinal Radiation Toxicity
    Role: Co-Investigator

    HU0001-09-1-0005     (HAUER-JENSEN, MARTIN)Jul 6, 2009 - Sep 30, 2011
    Uniformed Services University of the Health Sciences - Pass Through: Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.
    Synergistic Radioprotection of Gastrointestinal Tract by Gamma-Tocotrienol (GT3) and Statins: Efficacy and Mechanisms
    Role: Co-Investigator

    HDTRA1-07-C-0028     (HAUER-JENSEN, MARTIN)Jan 26, 2007 - Jan 25, 2010
    Defense Threat Reduction Agency
    Radiation Prophylaxis by Gamma-Tocotrienol
    Role: Co-Investigator

    U19AI67798     (HAUER-JENSEN, MARTIN)Aug 31, 2005 - Jul 31, 2010
    NIH/Nat. Inst. of Allergy & Infectious Diseases - Pass Through: Duke University
    Somatostatin analogues as countermeasures against intestinal radiation toxicity
    Role: Co-Investigator

    R01AR049794     (O'BRIEN, CHARLES A)Apr 1, 2003 - Mar 31, 2021
    NIH
    Osteocyte Control of Bone Remodeling
    Role: Co-Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Zhang Z, Fu Q, Wang J, Yang R, Xiao P, Ke F, Lu C. Interactions between butterfly-like prismatic dislocation loop pairs and planar defects in Ni3Al. Phys Chem Chem Phys. 2021 May 05; 23(17):10377-10383. PMID: 33884396.
      View in: PubMed
    2. Li Q, Cao M, Fu Q, Yang N, Yan X, Song L, Li C. Complement genes in black rockfish (Sebastods schlegelii): genome-wide identification, evolution and their potential functions in response to Vibrio anguillarum infection. Fish Shellfish Immunol. 2021 Apr 28; 114:119-131. PMID: 33930548.
      View in: PubMed
    3. Jin X, Cui L, Zhao W, Li X, Liu L, Li Y, Fu Q, Li D, Yu M, Du M. Decidualization-derived cAMP regulates phenotypic and functional conversion of decidual NK cells from CD56dimCD16- NK cells. Cell Mol Immunol. 2021 Mar 30. PMID: 33785840.
      View in: PubMed
    4. Han L, Wang T, Song G, Ma W, Fu Q, Yang Q, Liu X, Guo Y, Jiang H. Tunable peak power square-wave pulse based on an all-PM thulium-doped mode-locked fiber laser. Appl Opt. 2021 Mar 01; 60(7):1982-1986. PMID: 33690290.
      View in: PubMed
    5. Cao M, Yan X, Su B, Yang N, Fu Q, Xue T, Song L, Li Q, Li C. Integrated Analysis of circRNA-miRNA-mRNA Regulatory Networks in the Intestine of Sebastes schlegelii Following Edwardsiella tarda Challenge. Front Immunol. 2020; 11:618687. PMID: 33552082.
      View in: PubMed
    6. Fu Q, Xie S, Chen J, Huang H. Modified Culture System and Combination of FICTION Could Increase the Detection Rate of Abnormalities in Multiple Myeloma. Ann Clin Lab Sci. 2021 Jan; 51(1):61-72. PMID: 33653782.
      View in: PubMed
    7. Tian M, Xu D, Fu Q, Zhang L, Yang N, Xue T, Gao C, Zhu Q, Ren Y, Cao M, Tan F, Song L, Li C. Galectins in turbot (Scophthalmus maximus L.): Characterization and expression profiling in mucosal tissues. Fish Shellfish Immunol. 2021 Feb; 109:71-81. PMID: 33316369.
      View in: PubMed
    8. Wu J, Lin H, Chen C, Luo Y, Dai W, Lin X, Chen W, Fu Q, Yuan Q, Chen J. [Analysis of genetic and clinical characteristics of nine cases of myelodysplastic syndrome with near tetraploid/tetraploidy karyotype]. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2020 Dec 10; 37(12):1336-1339. PMID: 33306816.
      View in: PubMed
    9. Song L, Gao C, Xue T, Yang N, Fu Q, Zhu Q, Ge X, Li C. Characterization and expression analysis of mitochondrial localization molecule: NOD-like receptor X1 (Nlrx1) in mucosal tissues of turbot (Scophthalmus maximus) following bacterial challenge. Dev Comp Immunol. 2021 Mar; 116:103944. PMID: 33248045.
      View in: PubMed
    10. Liu M, Luo J, Chen J, Gao X, Fu Q, Zhang J. Unique Slow Crack Growth Behavior of Isotactic Polypropylene: The Role of Shear Layer-Spherulites Layer Alternated Structure. Polymers (Basel). 2020 Nov 20; 12(11). PMID: 33233624.
      View in: PubMed
    11. Liu X, Fu Q, Tang Y, Deng JH, Mei D, Zhang B. A case report of neurological adverse events caused by short-term and low-dose treatment of mitotane: The role of therapeutic drug monitoring. Medicine (Baltimore). 2020 Oct 02; 99(40):e22620. PMID: 33019484.
      View in: PubMed
    12. Sun J, Wang L, Yang W, Wang L, Fu Q, Song L. IgIT-Mediated Signaling Inhibits the Antimicrobial Immune Response in Oyster Hemocytes. J Immunol. 2020 11 01; 205(9):2402-2413. PMID: 32989090.
      View in: PubMed
    13. Guan YH, Chen J, Chen LJ, Jiang XX, Fu Q. Comparison of UV/H2O2, UV/PMS, and UV/PDS in Destruction of Different Reactivity Compounds and Formation of Bromate and Chlorate. Front Chem. 2020; 8:581198. PMID: 33102448.
      View in: PubMed
    14. Cui L, Bao H, Liu Z, Man X, Liu H, Hou Y, Luo Q, Wang S, Fu Q, Zhang H. hUMSCs regulate the differentiation of ovarian stromal cells via TGF-ß1/Smad3 signaling pathway to inhibit ovarian fibrosis to repair ovarian function in POI rats. Stem Cell Res Ther. 2020 09 07; 11(1):386. PMID: 32894203.
      View in: PubMed
    15. Zhang X, Fu Q, Xu L, Yang Y, Zhao W, Zhang Y, Mi W, Li H. Corrigendum to "Dexmedetomidine Postconditioning Alleviates Hypoxia/Reoxygenation Injury in Senescent Myocardial Cells by Regulating lncRNA H19 and m6A Modification". Oxid Med Cell Longev. 2020; 2020:7059751. PMID: 32936090.
      View in: PubMed
    16. Yang L, Fu Q, Miao L, Ding Q, Li X, Wang J, Jiang G, Wang Y. Quantitative acetylome and phosphorylome analysis reveals Girdin affects pancreatic cancer progression through regulating Cortactin. Aging (Albany NY). 2020 05 05; 12(9):7679-7693. PMID: 32369440.
      View in: PubMed
    17. Liu X, Gao Z, Fu Q, Song L, Zhang P, Zhang X, Hendrickson H, Crooks PA, Zhou D, Zheng G. Deuteration of the farnesyl terminal methyl groups of d-tocotrienol and its effects on the metabolic stability and ability of inducing G-CSF production. Bioorg Med Chem. 2020 06 01; 28(11):115498. PMID: 32291146.
      View in: PubMed
    18. Luo Q, Fu Q, Zhang X, Zhang H, Qin T. Application of Single-Cell RNA Sequencing in Pancreatic Cancer and the Endocrine Pancreas. Adv Exp Med Biol. 2020; 1255:143-152. PMID: 32949397.
      View in: PubMed
    19. Banerjee S, Fu Q, Shah SK, Melnyk SB, Sterneck E, Hauer-Jensen M, Pawar SA. C/EBPd protects from radiation-induced intestinal injury and sepsis by suppression of inflammatory and nitrosative stress. Sci Rep. 2019 09 27; 9(1):13953. PMID: 31562350.
      View in: PubMed
    20. Fu Q, Gao Y, Zhao H, Wang Z, Wang J. Galangin protects human rheumatoid arthritis fibroblast-like synoviocytes via suppression of the NF-?B/NLRP3 pathway. Mol Med Rep. 2018 Oct; 18(4):3619-3624. PMID: 30152847.
      View in: PubMed
    21. Deng L, Peng Y, Jiang Y, Wu Y, Ding Y, Wang Y, Xu D, Fu Q. Imipramine Protects against Bone Loss by Inhibition of Osteoblast-Derived Microvesicles. Int J Mol Sci. 2017 May 08; 18(5). PMID: 28481322.
      View in: PubMed
    22. Wu Y, Wang M, Peng Y, Ding Y, Deng L, Fu Q. Overexpression of Arl6ip5 in osteoblast regulates RANKL subcellualr localization. Biochem Biophys Res Commun. 2015 Sep 04; 464(4):1275-1281. PMID: 26220341.
      View in: PubMed
    23. Deng L, Wang Y, Peng Y, Wu Y, Ding Y, Jiang Y, Shen Z, Fu Q. Osteoblast-derived microvesicles: A novel mechanism for communication between osteoblasts and osteoclasts. Bone. 2015 Oct; 79:37-42. PMID: 26013558.
      View in: PubMed
    24. Deng L, Ding Y, Peng Y, Wu Y, Fan J, Li W, Yang R, Yang M, Fu Q. ?-Tocotrienol protects against ovariectomy-induced bone loss via mevalonate pathway as HMG-CoA reductase inhibitor. Bone. 2014 Oct; 67:200-7. PMID: 25019595.
      View in: PubMed
    25. Deng L, Peng Y, Wu Y, Yang M, Ding Y, Chen Q, Fu Q. Tissue distribution of emulsified ?-tocotrienol and its long-term biological effects after subcutaneous administration. Lipids Health Dis. 2014 Apr 09; 13:66. PMID: 24712339.
      View in: PubMed
    26. Peng Y, Deng L, Ding Y, Chen Q, Wu Y, Yang M, Wang Y, Fu Q. Comparative study of somatostatin-human serum albumin fusion proteins and natural somatostatin on receptor binding, internalization and activation. PLoS One. 2014; 9(2):e89932. PMID: 24587133.
      View in: PubMed
    27. Pathak R, Pawar SA, Fu Q, Gupta PK, Berbée M, Garg S, Sridharan V, Wang W, Biju PG, Krager KJ, Boerma M, Ghosh SP, Cheema AK, Hendrickson HP, Aykin-Burns N, Hauer-Jensen M. Characterization of transgenic Gfrp knock-in mice: implications for tetrahydrobiopterin in modulation of normal tissue radiation responses. Antioxid Redox Signal. 2014 Mar 20; 20(9):1436-46. PMID: 23521531.
      View in: PubMed
    28. Onal M, Galli C, Fu Q, Xiong J, Weinstein RS, Manolagas SC, O'Brien CA. The RANKL distal control region is required for the increase in RANKL expression, but not the bone loss, associated with hyperparathyroidism or lactation in adult mice. Mol Endocrinol. 2012 Feb; 26(2):341-8. PMID: 22207718.
      View in: PubMed
    29. Fu Q, Berbée M, Wang W, Boerma M, Wang J, Schmid HA, Hauer-Jensen M. Preclinical evaluation of Som230 as a radiation mitigator in a mouse model: postexposure time window and mechanisms of action. Radiat Res. 2011 Jun; 175(6):728-35. PMID: 21529145.
      View in: PubMed
    30. Berbée M, Fu Q, Boerma M, Sree Kumar K, Loose DS, Hauer-Jensen M. Mechanisms underlying the radioprotective properties of ?-tocotrienol: comparative gene expression profiling in tocol-treated endothelial cells. Genes Nutr. 2012 Jan; 7(1):75-81. PMID: 21516479.
      View in: PubMed
    31. Berbée M, Fu Q, Garg S, Kulkarni S, Kumar KS, Hauer-Jensen M. Pentoxifylline enhances the radioprotective properties of ?-tocotrienol: differential effects on the hematopoietic, gastrointestinal and vascular systems. Radiat Res. 2011 Mar; 175(3):297-306. PMID: 21388273.
      View in: PubMed
    32. Berbée M, Fu Q, Kumar KS, Hauer-Jensen M. Novel strategies to ameliorate radiation injury: a possible role for tetrahydrobiopterin. Curr Drug Targets. 2010 Nov; 11(11):1366-74. PMID: 20583982.
      View in: PubMed
    33. Berbee M, Fu Q, Boerma M, Pathak R, Zhou D, Kumar KS, Hauer-Jensen M. Reduction of radiation-induced vascular nitrosative stress by the vitamin E analog ?-tocotrienol: evidence of a role for tetrahydrobiopterin. Int J Radiat Oncol Biol Phys. 2011 Mar 01; 79(3):884-91. PMID: 20950957.
      View in: PubMed
    34. Cui L, Pierce D, Light KE, Melchert RB, Fu Q, Kumar KS, Hauer-Jensen M. Sublethal total body irradiation leads to early cerebellar damage and oxidative stress. Curr Neurovasc Res. 2010 May; 7(2):125-35. PMID: 20334614.
      View in: PubMed
    35. Garg S, Boerma M, Wang J, Fu Q, Loose DS, Kumar KS, Hauer-Jensen M. Influence of sublethal total-body irradiation on immune cell populations in the intestinal mucosa. Radiat Res. 2010 Apr; 173(4):469-78. PMID: 20334519.
      View in: PubMed
    36. Fu Q, Berbée M, Boerma M, Wang J, Schmid HA, Hauer-Jensen M. The somatostatin analog SOM230 (pasireotide) ameliorates injury of the intestinal mucosa and increases survival after total-body irradiation by inhibiting exocrine pancreatic secretion. Radiat Res. 2009 Jun; 171(6):698-707. PMID: 19580476.
      View in: PubMed
    37. Berbée M, Fu Q, Boerma M, Wang J, Kumar KS, Hauer-Jensen M. gamma-Tocotrienol ameliorates intestinal radiation injury and reduces vascular oxidative stress after total-body irradiation by an HMG-CoA reductase-dependent mechanism. Radiat Res. 2009 May; 171(5):596-605. PMID: 19580495.
      View in: PubMed
    38. Galli C, Fu Q, Wang W, Olsen BR, Manolagas SC, Jilka RL, O'Brien CA. Commitment to the osteoblast lineage is not required for RANKL gene expression. J Biol Chem. 2009 May 08; 284(19):12654-62. PMID: 19279010.
      View in: PubMed
    39. Boerma M, Fu Q, Wang J, Loose DS, Bartolozzi A, Ellis JL, McGonigle S, Paradise E, Sweetnam P, Fink LM, Vozenin-Brotons MC, Hauer-Jensen M. Comparative gene expression profiling in three primary human cell lines after treatment with a novel inhibitor of Rho kinase or atorvastatin. Blood Coagul Fibrinolysis. 2008 Oct; 19(7):709-18. PMID: 18832915.
      View in: PubMed
    40. Fu Q, Wang J, Boerma M, Berbée M, Qiu X, Fink LM, Hauer-Jensen M. Involvement of heat shock factor 1 in statin-induced transcriptional upregulation of endothelial thrombomodulin. Circ Res. 2008 Aug 15; 103(4):369-77. PMID: 18599869.
      View in: PubMed
    41. Galli C, Zella LA, Fretz JA, Fu Q, Pike JW, Weinstein RS, Manolagas SC, O'Brien CA. Targeted deletion of a distant transcriptional enhancer of the receptor activator of nuclear factor-kappaB ligand gene reduces bone remodeling and increases bone mass. Endocrinology. 2008 Jan; 149(1):146-53. PMID: 17932217.
      View in: PubMed
    42. Wang J, Boerma M, Fu Q, Kulkarni A, Fink LM, Hauer-Jensen M. Simvastatin ameliorates radiation enteropathy development after localized, fractionated irradiation by a protein C-independent mechanism. Int J Radiat Oncol Biol Phys. 2007 Aug 01; 68(5):1483-90. PMID: 17674978.
      View in: PubMed
    43. Wang J, Boerma M, Fu Q, Hauer-Jensen M. Significance of endothelial dysfunction in the pathogenesis of early and delayed radiation enteropathy. World J Gastroenterol. 2007 Jun 14; 13(22):3047-55. PMID: 17589919.
      View in: PubMed
    44. Hauer-Jensen M, Wang J, Boerma M, Fu Q, Denham JW. Radiation damage to the gastrointestinal tract: mechanisms, diagnosis, and management. Curr Opin Support Palliat Care. 2007 Apr; 1(1):23-9. PMID: 18660720.
      View in: PubMed
    45. Wang J, Boerma M, Fu Q, Hauer-Jensen M. Radiation responses in skin and connective tissues: effect on wound healing and surgical outcome. Hernia. 2006 Dec; 10(6):502-6. PMID: 17047884.
      View in: PubMed
    46. Fu Q, Manolagas SC, O'Brien CA. Parathyroid hormone controls receptor activator of NF-kappaB ligand gene expression via a distant transcriptional enhancer. Mol Cell Biol. 2006 Sep; 26(17):6453-68. PMID: 16914731.
      View in: PubMed
    47. Bellido T, Ali AA, Gubrij I, Plotkin LI, Fu Q, O'Brien CA, Manolagas SC, Jilka RL. Chronic elevation of parathyroid hormone in mice reduces expression of sclerostin by osteocytes: a novel mechanism for hormonal control of osteoblastogenesis. Endocrinology. 2005 Nov; 146(11):4577-83. PMID: 16081646.
      View in: PubMed
    48. O'Brien CA, Jilka RL, Fu Q, Stewart S, Weinstein RS, Manolagas SC. IL-6 is not required for parathyroid hormone stimulation of RANKL expression, osteoclast formation, and bone loss in mice. Am J Physiol Endocrinol Metab. 2005 Nov; 289(5):E784-93. PMID: 15956054.
      View in: PubMed
    49. Bellido T, Ali AA, Plotkin LI, Fu Q, Gubrij I, Roberson PK, Weinstein RS, O'Brien CA, Manolagas SC, Jilka RL. Proteasomal degradation of Runx2 shortens parathyroid hormone-induced anti-apoptotic signaling in osteoblasts. A putative explanation for why intermittent administration is needed for bone anabolism. J Biol Chem. 2003 Dec 12; 278(50):50259-72. PMID: 14523023.
      View in: PubMed
    50. Kousteni S, Chen JR, Bellido T, Han L, Ali AA, O'Brien CA, Plotkin L, Fu Q, Mancino AT, Wen Y, Vertino AM, Powers CC, Stewart SA, Ebert R, Parfitt AM, Weinstein RS, Jilka RL, Manolagas SC. Reversal of bone loss in mice by nongenotropic signaling of sex steroids. Science. 2002 Oct 25; 298(5594):843-6. PMID: 12399595.
      View in: PubMed
    51. Fu Q, Jilka RL, Manolagas SC, O'Brien CA. Parathyroid hormone stimulates receptor activator of NFkappa B ligand and inhibits osteoprotegerin expression via protein kinase A activation of cAMP-response element-binding protein. J Biol Chem. 2002 Dec 13; 277(50):48868-75. PMID: 12364326.
      View in: PubMed
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