 Exosomes
"Exosomes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Vesicles secreted from MULTIVESICULAR BODIES into the extracellular environment when the multivesicular bodies fuse with the PLASMA MEMBRANE. Multivesicular bodies are formed from ENDOSOMES when they accumulate vesicles (sometimes referred to as "intraluminal vesicles") from inward budding of the endosome membrane.
| Descriptor ID |
D055354
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| MeSH Number(s) |
A11.284.430.214.190.875.190.880.495
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Exosomes".
Below are MeSH descriptors whose meaning is more specific than "Exosomes".
This graph shows the total number of publications written about "Exosomes" by people in UAMS Profiles by year, and whether "Exosomes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2025 | 2 | 1 | 3 | | 2024 | 1 | 0 | 1 | | 2023 | 0 | 1 | 1 | | 2022 | 3 | 0 | 3 | | 2021 | 4 | 0 | 4 | | 2020 | 2 | 1 | 3 | | 2019 | 2 | 0 | 2 | | 2018 | 6 | 1 | 7 | | 2016 | 1 | 3 | 4 | | 2015 | 1 | 1 | 2 | | 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Exosomes" by people in Profiles over the past ten years.
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Feng C, Li R, Wang G, Liu S, Fu Q. Dynamic negative pressure enhances MSC-derived exosomes treatment for vessel injury-related erectile dysfunction by facilitating cavernous diffusion. Int J Pharm. 2025 Sep 15; 682:125999.
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Fu Q, Qiu R, Tang Q, Li X, Li Y, Qin Y, Li Q, Yao J, Jiang Z, Xu H, Cheng Y. Exosomes from high-altitude cerebral edema patients induce cognitive dysfunction by altering oxidative stress responses in mice. Transl Psychiatry. 2025 Jul 22; 15(1):253.
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Li X, Fu Q, Guo M, Du Y, Cheng Y. Unlocking Parkinson's disease: the role of microRNAs in regulation, diagnosis, and therapy. Apoptosis. 2025 06; 30(5-6):1272-1291.
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Tiwari P, Shukla RP, Yadav K, Sharma M, Bakshi AK, Panwar D, Singh N, Agarwal N, Mugale MN, Mishra PR. YIGSR Functionalized Hybrid Exosomes Spatially Target Dasatinib to Laminin Receptors for Precision Therapy in Breast Cancer. Adv Healthc Mater. 2025 Apr; 14(9):e2402673.
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Kilic F. The Coordinated Changes in Platelet Glycan Patterns with Blood Serotonin and Exosomes. Int J Mol Sci. 2024 Nov 06; 25(22).
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Mainali N, Li X, Wang X, Balasubramaniam M, Ganne A, Kore R, Shmookler Reis RJ, Mehta JL, Ayyadevara S. Myocardial infarction elevates endoplasmic reticulum stress and protein aggregation in heart as well as brain. Mol Cell Biochem. 2024 Oct; 479(10):2741-2753.
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Xiao H, Ye X, Vishwakarma V, Preet R, Dixon DA. CRC-derived exosomes containing the RNA binding protein HuR promote lung cell proliferation by stabilizing c-Myc mRNA. Cancer Biol Ther. 2022 12 31; 23(1):139-149.
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Liu S, Li R, Dou K, Li K, Zhou Q, Fu Q. Injectable thermo-sensitive hydrogel containing ADSC-derived exosomes for the treatment of cavernous nerve injury. Carbohydr Polym. 2023 Jan 15; 300:120226.
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Zubair M, Hamzah R, Griffin R, Ali N. Identification and functional characterization of multiple inositol polyphosphate phosphatase1 (Minpp1) isoform-2 in exosomes with potential to modulate tumor microenvironment. PLoS One. 2022; 17(3):e0264451.
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Wang L, Cheng W, Zhu J, Li W, Li D, Yang X, Zhao W, Ren M, Ren J, Mo X, Fu Q, Zhang K. Electrospun nanoyarn and exosomes of adipose-derived stem cells for urethral regeneration: Evaluations in vitro and in vivo. Colloids Surf B Biointerfaces. 2022 Jan; 209(Pt 2):112218.
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Kore RA, Wang X, Henson JC, Ding Z, Jamshidi-Parsian A, Mehta JL. Proteomic basis of modulation of postischemic fibrosis by MSC exosomes. Am J Physiol Regul Integr Comp Physiol. 2021 11 01; 321(5):R639-R654.
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Hamzah RN, Alghazali KM, Biris AS, Griffin RJ. Exosome Traceability and Cell Source Dependence on Composition and Cell-Cell Cross Talk. Int J Mol Sci. 2021 May 19; 22(10).
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Kore RA, Wang X, Ding Z, Griffin RJ, Tackett AJ, Mehta JL. MSC exosome-mediated cardioprotection in ischemic mouse heart comparative proteomics of infarct and peri-infarct areas. Mol Cell Biochem. 2021 Apr; 476(4):1691-1704.
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Davies BA, Morton LO, Jefferson JR, Rozeveld CN, Doskey LC, LaRusso NF, Katzmann DJ. Polarized human cholangiocytes release distinct populations of apical and basolateral small extracellular vesicles. Mol Biol Cell. 2020 10 15; 31(22):2463-2474.
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Sharma KD, Schaal D, Kore RA, Hamzah RN, Pandanaboina SC, Hayar A, Griffin RJ, Srivatsan M, Reyna NS, Xie JY. Glioma-derived exosomes drive the differentiation of neural stem cells to astrocytes. PLoS One. 2020; 15(7):e0234614.
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Huang X, Sun L, Wen S, Deng D, Wan F, He X, Tian L, Liang L, Wei C, Gao K, Fu Q, Li Y, Jiang J, Zhai R, He M. RNA sequencing of plasma exosomes revealed novel functional long noncoding RNAs in hepatocellular carcinoma. Cancer Sci. 2020 Sep; 111(9):3338-3349.
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Kore RA, Henson JC, Hamzah RN, Griffin RJ, Tackett AJ, Ding Z, Mehta JL. Molecular events in MSC exosome mediated cytoprotection in cardiomyocytes. Sci Rep. 2019 12 17; 9(1):19276.
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Zhang Q, Higginbotham JN, Jeppesen DK, Yang YP, Li W, McKinley ET, Graves-Deal R, Ping J, Britain CM, Dorsett KA, Hartman CL, Ford DA, Allen RM, Vickers KC, Liu Q, Franklin JL, Bellis SL, Coffey RJ. Transfer of Functional Cargo in Exomeres. Cell Rep. 2019 04 16; 27(3):940-954.e6.
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Aguilar-Lozano A, Baier S, Grove R, Shu J, Giraud D, Leiferman A, Mercer KE, Cui J, Badger TM, Adamec J, Andres A, Zempleni J. Concentrations of Purine Metabolites Are Elevated in Fluids from Adults and Infants and in Livers from Mice Fed Diets Depleted of Bovine Milk Exosomes and their RNA Cargos. J Nutr. 2018 12 01; 148(12):1886-1894.
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Fujiwara T, Eguchi T, Sogawa C, Ono K, Murakami J, Ibaragi S, Asaumi JI, Calderwood SK, Okamoto K, Kozaki KI. Carcinogenic epithelial-mesenchymal transition initiated by oral cancer exosomes is inhibited by anti-EGFR antibody cetuximab. Oral Oncol. 2018 11; 86:251-257.
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Jamshidi-Parsian A, Griffin RJ, Kore RA, Todorova VK, Makhoul I. Tumor-endothelial cell interaction in an experimental model of human hepatocellular carcinoma. Exp Cell Res. 2018 11 01; 372(1):16-24.
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Ni J, Li H, Zhou Y, Gu B, Xu Y, Fu Q, Peng X, Cao N, Fu Q, Jin M, Sun G, Wang J, Jin Y, Liu F. Therapeutic Potential of Human Adipose-Derived Stem Cell Exosomes in Stress Urinary Incontinence - An in Vitro and in Vivo Study. Cell Physiol Biochem. 2018; 48(4):1710-1722.
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Patel NA, Moss LD, Lee JY, Tajiri N, Acosta S, Hudson C, Parag S, Cooper DR, Borlongan CV, Bickford PC. Long noncoding RNA MALAT1 in exosomes drives regenerative function and modulates inflammation-linked networks following traumatic brain injury. J Neuroinflammation. 2018 Jul 12; 15(1):204.
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Haemmerle M, Stone RL, Menter DG, Afshar-Kharghan V, Sood AK. The Platelet Lifeline to Cancer: Challenges and Opportunities. Cancer Cell. 2018 06 11; 33(6):965-983.
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Eguchi T, Sogawa C, Okusha Y, Uchibe K, Iinuma R, Ono K, Nakano K, Murakami J, Itoh M, Arai K, Fujiwara T, Namba Y, Murata Y, Ohyama K, Shimomura M, Okamura H, Takigawa M, Nakatsura T, Kozaki KI, Okamoto K, Calderwood SK. Organoids with cancer stem cell-like properties secrete exosomes and HSP90 in a 3D nanoenvironment. PLoS One. 2018; 13(2):e0191109.
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Nolan J, Sarimollaoglu M, Nedosekin DA, Jamshidi-Parsian A, Galanzha EI, Kore RA, Griffin RJ, Zharov VP. In Vivo Flow Cytometry of Circulating Tumor-Associated Exosomes. Anal Cell Pathol (Amst). 2016; 2016:1628057.
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Fry CS, Kirby TJ, Kosmac K, McCarthy JJ, Peterson CA. Myogenic Progenitor Cells Control Extracellular Matrix Production by Fibroblasts during Skeletal Muscle Hypertrophy. Cell Stem Cell. 2017 01 05; 20(1):56-69.
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Ehrlich S, Lambers D, Baccarelli A, Khoury J, Macaluso M, Ho SM. Endocrine Disruptors: A Potential Risk Factor for Gestational Diabetes Mellitus. Am J Perinatol. 2016 11; 33(13):1313-1318.
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Liu Y, Bailey JC, Helwa I, Dismuke WM, Cai J, Drewry M, Brilliant MH, Budenz DL, Christen WG, Chasman DI, Fingert JH, Gaasterland D, Gaasterland T, Gordon MO, Igo RP, Kang JH, Kass MA, Kraft P, Lee RK, Lichter P, Moroi SE, Realini A, Richards JE, Ritch R, Schuman JS, Scott WK, Singh K, Sit AJ, Song YE, Vollrath D, Weinreb R, Medeiros F, Wollstein G, Zack DJ, Zhang K, Pericak-Vance MA, Gonzalez P, Stamer WD, Kuchtey J, Kuchtey RW, Allingham RR, Hauser MA, Pasquale LR, Haines JL, Wiggs JL. A Common Variant in MIR182 Is Associated With Primary Open-Angle Glaucoma in the NEIGHBORHOOD Consortium. Invest Ophthalmol Vis Sci. 2016 08 01; 57(10):4528-4535.
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Kore RA, Abraham EC. Phosphorylation negatively regulates exosome mediated secretion of cryAB in glioma cells. Biochim Biophys Acta. 2016 Feb; 1863(2):368-77.
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Enriquez VA, Cleys ER, Da Silveira JC, Spillman MA, Winger QA, Bouma GJ. High LIN28A Expressing Ovarian Cancer Cells Secrete Exosomes That Induce Invasion and Migration in HEK293 Cells. Biomed Res Int. 2015; 2015:701390.
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