 Tetrahydroisoquinolines
"Tetrahydroisoquinolines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of ISOQUINOLINES in which the nitrogen containing ring is protonated. They derive from the non-enzymatic Pictet-Spengler condensation of CATECHOLAMINES with ALDEHYDES.
| Descriptor ID |
D044005
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| MeSH Number(s) |
D03.438.531.820
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| Concept/Terms |
Tetrahydroisoquinolines- Tetrahydroisoquinolines
- 1,2,3,4-Tetrahydroisoquinolines
- Tetrahydro-Isoquinolines
- Tetrahydro Isoquinolines
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Below are MeSH descriptors whose meaning is more general than "Tetrahydroisoquinolines".
Below are MeSH descriptors whose meaning is more specific than "Tetrahydroisoquinolines".
This graph shows the total number of publications written about "Tetrahydroisoquinolines" by people in UAMS Profiles by year, and whether "Tetrahydroisoquinolines" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 0 | 1 | | 2016 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 | | 2013 | 1 | 0 | 1 | | 2012 | 2 | 0 | 2 | | 2002 | 1 | 0 | 1 |
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Below are the most recent publications written about "Tetrahydroisoquinolines" by people in Profiles over the past ten years.
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Wells AM, Ridener E, Bourbonais CA, Kim W, Pantazopoulos H, Carroll FI, Kim KS, Cohen BM, Carlezon WA. Effects of Chronic Social Defeat Stress on Sleep and Circadian Rhythms Are Mitigated by Kappa-Opioid Receptor Antagonism. J Neurosci. 2017 08 09; 37(32):7656-7668.
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Owens SM, Pollard GT, Howard JL, Fennell TR, Snyder RW, Carroll FI. Pharmacodynamic Relationships between Duration of Action of JDTic-like Kappa-Opioid Receptor Antagonists and Their Brain and Plasma Pharmacokinetics in Rats. ACS Chem Neurosci. 2016 12 21; 7(12):1737-1745.
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Molden BM, Cooney KA, West K, Van Der Ploeg LH, Baldini G. Temporal cAMP Signaling Selectivity by Natural and Synthetic MC4R Agonists. Mol Endocrinol. 2015 Nov; 29(11):1619-33.
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Munro TA, Huang XP, Inglese C, Perrone MG, Van't Veer A, Carroll FI, Béguin C, Carlezon WA, Colabufo NA, Cohen BM, Roth BL. Selective ? opioid antagonists nor-BNI, GNTI and JDTic have low affinities for non-opioid receptors and transporters. PLoS One. 2013; 8(8):e70701.
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Van't Veer A, Yano JM, Carroll FI, Cohen BM, Carlezon WA. Corticotropin-releasing factor (CRF)-induced disruption of attention in rats is blocked by the ?-opioid receptor antagonist JDTic. Neuropsychopharmacology. 2012 Dec; 37(13):2809-16.
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Munro TA, Berry LM, Van't Veer A, Béguin C, Carroll FI, Zhao Z, Carlezon WA, Cohen BM. Long-acting ? opioid antagonists nor-BNI, GNTI and JDTic: pharmacokinetics in mice and lipophilicity. BMC Pharmacol. 2012 May 29; 12:5.
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