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Kartik Balachandran

TitleProfessor - Engineering
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentBMEG | Biomedical Engineering
Address1 University of Arkansas
Fayetteville AR 72701
Phone+1 (479) 5753376
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Dunn CS, Ferreira LA, Venier SM, Ali SF, Wolchok JC, Balachandran K. Functional Analysis of the Cortical Transcriptome and Proteome Reveal Neurogenesis, Inflammation, and Cell Death after Repeated Traumatic Brain Injury In vivo. Neurotrauma Rep. 2022; 3(1):224-239. PMID: 35919509.
      View in: PubMed
    2. Ravishankar P, Tandon I, Balachandran K. Effect of Cyclic Uniaxial Mechanical Strain on Endothelial Progenitor Cell Differentiation. Cardiovasc Eng Technol. 2022 12; 13(6):872-885. PMID: 35501625.
      View in: PubMed
    3. Tandon I, Ozkizilcik A, Ravishankar P, Balachandran K. Aortic valve cell microenvironment: Considerations for developing a valve-on-chip. Biophys Rev (Melville). 2021 Dec; 2(4):041303. PMID: 38504720.
      View in: PubMed
    4. Ozkizilcik A, Sysavanh F, Patel S, Tandon I, Balachandran K. Local Renin-Angiotensin System Signaling Mediates Cellular Function of Aortic Valves. Ann Biomed Eng. 2021 Dec; 49(12):3550-3562. PMID: 34704164.
      View in: PubMed
    5. Dunn C, Sturdivant N, Venier S, Ali S, Wolchok J, Balachandran K. Blood-Brain Barrier Breakdown and Astrocyte Reactivity Evident in the Absence of Behavioral Changes after Repeated Traumatic Brain Injury. Neurotrauma Rep. 2021; 2(1):399-410. PMID: 34901939.
      View in: PubMed
    6. Tandon I, Quinn KP, Balachandran K. Label-Free Multiphoton Microscopy for the Detection and Monitoring of Calcific Aortic Valve Disease. Front Cardiovasc Med. 2021; 8:688513. PMID: 34179147.
      View in: PubMed
    7. Tandon I, Johns S, Woessner A, Perez J, Cross D, Ozkizilcik A, Muldoon TJ, Vallurupalli S, Padala M, Quinn KP, Balachandran K. Label-free optical biomarkers detect early calcific aortic valve disease in a wild-type mouse model. BMC Cardiovasc Disord. 2020 12 11; 20(1):521. PMID: 33308143.
      View in: PubMed
    8. Ravishankar P, Ozkizilcik A, Husain A, Balachandran K. Anisotropic Fiber-Reinforced Glycosaminoglycan Hydrogels for Heart Valve Tissue Engineering. Tissue Eng Part A. 2021 05; 27(9-10):513-525. PMID: 32723024.
      View in: PubMed
    9. Tandon I, Kolenc OI, Cross D, Vargas I, Johns S, Quinn KP, Balachandran K. Label-free metabolic biomarkers for assessing valve interstitial cell calcific progression. Sci Rep. 2020 06 25; 10(1):10317. PMID: 32587322.
      View in: PubMed
    10. Lam NT, Tandon I, Balachandran K. The role of fibroblast growth factor 1 and 2 on the pathological behavior of valve interstitial cells in a three-dimensional mechanically-conditioned model. J Biol Eng. 2019; 13:45. PMID: 31149027.
      View in: PubMed
    11. Walker A, Kim J, Wyatt J, Terlouw A, Balachandran K, Wolchok J. Repeated In Vitro Impact Conditioning of Astrocytes Decreases the Expression and Accumulation of Extracellular Matrix. Ann Biomed Eng. 2019 Apr; 47(4):967-979. PMID: 30706307.
      View in: PubMed
    12. Rosas-Hernandez H, Cuevas E, Escudero-Lourdes C, Lantz SM, Sturdivant NM, Imam SZ, Sarkar S, Slikker W, Paule MG, Balachandran K, Ali SF. Characterization of uniaxial high-speed stretch as an in vitro model of mild traumatic brain injury on the blood-brain barrier. Neurosci Lett. 2018 04 13; 672:123-129. PMID: 29458086.
      View in: PubMed
    13. Rosas-Hernandez H, Cuevas E, Escudero-Lourdes C, Lantz SM, Gomez-Crisostomo NP, Sturdivant NM, Balachandran K, Imam SZ, Slikker W, Paule MG, Ali SF. Characterization of Biaxial Stretch as an In Vitro Model of Traumatic Brain Injury to the Blood-Brain Barrier. Mol Neurobiol. 2018 01; 55(1):258-266. PMID: 28842857.
      View in: PubMed
    14. Ravishankar P, Zeballos MA, Balachandran K. Isolation of Endothelial Progenitor Cells from Human Umbilical Cord Blood. J Vis Exp. 2017 09 14; (127). PMID: 28994769.
      View in: PubMed
    15. Lam NT, Lam H, Sturdivant NM, Balachandran K. Fabrication of a matrigel-collagen semi-interpenetrating scaffold for use in dynamic valve interstitial cell culture. Biomed Mater. 2017 Jul 24; 12(4):045013. PMID: 28484097.
      View in: PubMed
    16. Perez J, Diaz N, Tandon I, Plate R, Martindale C, Balachandran K. Elevated Serotonin Interacts with Angiotensin-II to Result in Altered Valve Interstitial Cell Contractility and Remodeling. Cardiovasc Eng Technol. 2018 06; 9(2):168-180. PMID: 28247311.
      View in: PubMed
    17. Lam NT, Muldoon TJ, Quinn KP, Rajaram N, Balachandran K. Valve interstitial cell contractile strength and metabolic state are dependent on its shape. Integr Biol (Camb). 2016 10 10; 8(10):1079-1089. PMID: 27713997.
      View in: PubMed
    18. Khang A, Ravishankar P, Krishnaswamy A, Anderson PK, Cone SG, Liu Z, Qian X, Balachandran K. Engineering anisotropic biphasic Janus-type polymer nanofiber scaffold networks via centrifugal jet spinning. J Biomed Mater Res B Appl Biomater. 2017 Nov; 105(8):2455-2464. PMID: 27652573.
      View in: PubMed
    19. Sturdivant NM, Smith SG, Ali SF, Wolchok JC, Balachandran K. Acetazolamide Mitigates Astrocyte Cellular Edema Following Mild Traumatic Brain Injury. Sci Rep. 2016 09 14; 6:33330. PMID: 27623738.
      View in: PubMed
    20. Tandon I, Razavi A, Ravishankar P, Walker A, Sturdivant NM, Lam NT, Wolchok JC, Balachandran K. Valve interstitial cell shape modulates cell contractility independent of cell phenotype. J Biomech. 2016 10 03; 49(14):3289-3297. PMID: 27567567.
      View in: PubMed
    21. Lam NT, Balachandran K. The mechanobiology of drug-induced cardiac valve disease. J Long Term Eff Med Implants. 2015; 25(1-2):27-40. PMID: 25955005.
      View in: PubMed
    22. Badrossamay MR, Balachandran K, Capulli AK, Golecki HM, Agarwal A, Goss JA, Kim H, Shin K, Parker KK. Engineering hybrid polymer-protein super-aligned nanofibers via rotary jet spinning. Biomaterials. 2014 Mar; 35(10):3188-97. PMID: 24456606.
      View in: PubMed
    23. Greening GJ, Istfan R, Higgins LM, Balachandran K, Roblyer D, Pierce MC, Muldoon TJ. Characterization of thin poly(dimethylsiloxane)-based tissue-simulating phantoms with tunable reduced scattering and absorption coefficients at visible and near-infrared wavelengths. J Biomed Opt. 2014; 19(11):115002. PMID: 25387084.
      View in: PubMed
    24. Balachandran K, Alford PW, Wylie-Sears J, Goss JA, Grosberg A, Bischoff J, Aikawa E, Levine RA, Parker KK. Cyclic strain induces dual-mode endothelial-mesenchymal transformation of the cardiac valve. Proc Natl Acad Sci U S A. 2011 Dec 13; 108(50):19943-8. PMID: 22123981.
      View in: PubMed
    25. Balachandran K, Hussain S, Yap CH, Padala M, Chester AH, Yoganathan AP. Elevated cyclic stretch and serotonin result in altered aortic valve remodeling via a mechanosensitive 5-HT(2A) receptor-dependent pathway. Cardiovasc Pathol. 2012 May-Jun; 21(3):206-13. PMID: 21865058.
      View in: PubMed
    26. Balachandran K, Sucosky P, Yoganathan AP. Hemodynamics and mechanobiology of aortic valve inflammation and calcification. Int J Inflam. 2011; 2011:263870. PMID: 21760982.
      View in: PubMed
    27. Balachandran K, Bakay MA, Connolly JM, Zhang X, Yoganathan AP, Levy RJ. Aortic valve cyclic stretch causes increased remodeling activity and enhanced serotonin receptor responsiveness. Ann Thorac Surg. 2011 Jul; 92(1):147-53. PMID: 21718840.
      View in: PubMed
    28. Weiler M, Yap CH, Balachandran K, Padala M, Yoganathan AP. Regional analysis of dynamic deformation characteristics of native aortic valve leaflets. J Biomech. 2011 May 17; 44(8):1459-65. PMID: 21458817.
      View in: PubMed
    29. Thayer P, Balachandran K, Rathan S, Yap CH, Arjunon S, Jo H, Yoganathan AP. The effects of combined cyclic stretch and pressure on the aortic valve interstitial cell phenotype. Ann Biomed Eng. 2011 Jun; 39(6):1654-67. PMID: 21347552.
      View in: PubMed
    30. Padala M, Sacks MS, Liou SW, Balachandran K, He Z, Yoganathan AP. Mechanics of the mitral valve strut chordae insertion region. J Biomech Eng. 2010 Aug; 132(8):081004. PMID: 20670053.
      View in: PubMed
    31. Balachandran K, Sucosky P, Jo H, Yoganathan AP. Elevated cyclic stretch induces aortic valve calcification in a bone morphogenic protein-dependent manner. Am J Pathol. 2010 Jul; 177(1):49-57. PMID: 20489151.
      View in: PubMed
    32. Yap CH, Kim HS, Balachandran K, Weiler M, Haj-Ali R, Yoganathan AP. Dynamic deformation characteristics of porcine aortic valve leaflet under normal and hypertensive conditions. Am J Physiol Heart Circ Physiol. 2010 Feb; 298(2):H395-405. PMID: 19915178.
      View in: PubMed
    33. El-Hamamsy I, Balachandran K, Yacoub MH, Stevens LM, Sarathchandra P, Taylor PM, Yoganathan AP, Chester AH. Endothelium-dependent regulation of the mechanical properties of aortic valve cusps. J Am Coll Cardiol. 2009 Apr 21; 53(16):1448-55. PMID: 19371829.
      View in: PubMed
    34. Balachandran K, Sucosky P, Jo H, Yoganathan AP. Elevated cyclic stretch alters matrix remodeling in aortic valve cusps: implications for degenerative aortic valve disease. Am J Physiol Heart Circ Physiol. 2009 Mar; 296(3):H756-64. PMID: 19151254.
      View in: PubMed
    35. Sucosky P, Balachandran K, Elhammali A, Jo H, Yoganathan AP. Altered shear stress stimulates upregulation of endothelial VCAM-1 and ICAM-1 in a BMP-4- and TGF-beta1-dependent pathway. Arterioscler Thromb Vasc Biol. 2009 Feb; 29(2):254-60. PMID: 19023092.
      View in: PubMed
    36. Sucosky P, Padala M, Elhammali A, Balachandran K, Jo H, Yoganathan AP. Design of an ex vivo culture system to investigate the effects of shear stress on cardiovascular tissue. J Biomech Eng. 2008 Jun; 130(3):035001. PMID: 18532871.
      View in: PubMed
    37. Balachandran K, Konduri S, Sucosky P, Jo H, Yoganathan AP. An ex vivo study of the biological properties of porcine aortic valves in response to circumferential cyclic stretch. Ann Biomed Eng. 2006 Nov; 34(11):1655-65. PMID: 17031600.
      View in: PubMed
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