 Interleukin-23
"Interleukin-23" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A heterodimeric cytokine that plays a role in innate and adaptive immune responses. Interleukin-23 is comprised of a unique 19 kDa subunit and 40 kDa subunit that is shared with INTERLEUKIN-12. It is produced by DENDRITIC CELLS; MACROPHAGES and a variety of other immune cells
| Descriptor ID |
D053759
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| MeSH Number(s) |
D12.644.276.374.465.759 D12.776.467.374.465.759 D23.529.374.465.759
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Interleukin-23".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-23".
This graph shows the total number of publications written about "Interleukin-23" by people in UAMS Profiles by year, and whether "Interleukin-23" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 | | 2015 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2012 | 0 | 1 | 1 | | 2009 | 0 | 2 | 2 | | 2008 | 0 | 1 | 1 | | 2006 | 0 | 1 | 1 |
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Below are the most recent publications written about "Interleukin-23" by people in Profiles over the past ten years.
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Gruver AM, Westfall MD, Ackermann BL, Hill S, Morrison RD, Bodo J, Lai KK, Gemperline DC, Hsi ED, Liebler DC, Schmitz J, Benschop RJ. Proteomic characterisations of ulcerative colitis endoscopic biopsies associate with clinically relevant histological measurements of disease severity. J Clin Pathol. 2022 Sep; 75(9):636-642.
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Berman HS, Villa NM, Shi VY, Hsiao JL. Guselkumab in the treatment of concomitant hidradenitis suppurativa, psoriasis, and Crohn's disease. J Dermatolog Treat. 2021 Mar; 32(2):261-263.
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Mangan PR, Su LJ, Jenny V, Tatum AL, Picarillo C, Skala S, Ditto N, Lin Z, Yang X, Cotter PZ, Shuster DJ, Song Y, Borowski V, Thomas RL, Heimrich EM, Devaux B, Das Gupta R, Carvajal I, McIntyre KW, Xie J, Zhao Q, Struthers M, Salter-Cid LM. Dual Inhibition of Interleukin-23 and Interleukin-17 Offers Superior Efficacy in Mouse Models of Autoimmunity. J Pharmacol Exp Ther. 2015 Aug; 354(2):152-65.
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Frazer LC, Scurlock AM, Zurenski MA, Riley MM, Mintus M, Pociask DA, Sullivan JE, Andrews CW, Darville T. IL-23 induces IL-22 and IL-17 production in response to Chlamydia muridarum genital tract infection, but the absence of these cytokines does not influence disease pathogenesis. Am J Reprod Immunol. 2013 Dec; 70(6):472-84.
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