 Caspase 3
"Caspase 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A short pro-domain caspase that plays an effector role in APOPTOSIS. It is activated by INITIATOR CASPASES such as CASPASE 9. Isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.
| Descriptor ID |
D053148
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| MeSH Number(s) |
D08.811.277.656.262.500.126.350.300 D08.811.277.656.300.200.126.350.300 D12.644.360.075.405.350.300 D12.776.476.075.405.350.300
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| Concept/Terms |
Procaspase-3- Procaspase-3
- Procaspase 3
- Pro-Caspase-3
- Pro Caspase 3
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Below are MeSH descriptors whose meaning is more general than "Caspase 3".
Below are MeSH descriptors whose meaning is more specific than "Caspase 3".
This graph shows the total number of publications written about "Caspase 3" by people in UAMS Profiles by year, and whether "Caspase 3" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2020 | 0 | 1 | 1 | | 2019 | 0 | 2 | 2 | | 2018 | 0 | 3 | 3 | | 2017 | 1 | 5 | 6 | | 2016 | 0 | 3 | 3 | | 2015 | 1 | 4 | 5 | | 2014 | 0 | 1 | 1 | | 2013 | 0 | 4 | 4 | | 2012 | 0 | 4 | 4 | | 2011 | 1 | 4 | 5 | | 2010 | 1 | 6 | 7 | | 2009 | 0 | 4 | 4 | | 2008 | 0 | 5 | 5 | | 2007 | 0 | 6 | 6 | | 2006 | 0 | 6 | 6 | | 2005 | 0 | 3 | 3 | | 2004 | 0 | 7 | 7 | | 2003 | 0 | 9 | 9 | | 2002 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 1999 | 0 | 2 | 2 | | 1998 | 0 | 3 | 3 | | 1997 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Caspase 3" by people in Profiles over the past ten years.
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Jin X, An C, Jiao B, Safirstein RL, Wang Y. AMP-activated protein kinase contributes to cisplatin-induced renal epithelial cell apoptosis and acute kidney injury. Am J Physiol Renal Physiol. 2020 12 01; 319(6):F1073-F1080.
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Sun Y, Nemec-Bakk AS, Mallik AU, Bagchi AK, Singal PK, Khaper N. Blueberry extract attenuates doxorubicin-induced damage in H9c2 cardiac cells 1. Can J Physiol Pharmacol. 2019 Sep; 97(9):880-884.
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de Lima-Seolin BG, Nemec-Bakk A, Forsyth H, Kirk S, da Rosa Araujo AS, Schenkel PC, Belló-Klein A, Khaper N. Bucindolol Modulates Cardiac Remodeling by Attenuating Oxidative Stress in H9c2 Cardiac Cells Exposed to Norepinephrine. Oxid Med Cell Longev. 2019; 2019:6325424.
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Choubey M, Ranjan A, Bora PS, Baltazar F, Martin LJ, Krishna A. Role of adiponectin as a modulator of testicular function during aging in mice. Biochim Biophys Acta Mol Basis Dis. 2019 02 01; 1865(2):413-427.
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Nafees S, Mehdi SH, Zafaryab M, Zeya B, Sarwar T, Rizvi MA. Synergistic Interaction of Rutin and Silibinin on Human Colon Cancer Cell Line. Arch Med Res. 2018 05; 49(4):226-234.
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Yu H, Harrison FE, Xia F. Altered DNA repair; an early pathogenic pathway in Alzheimer's disease and obesity. Sci Rep. 2018 04 04; 8(1):5600.
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Kendrick S, Muranyi A, Gokhale V, Hurley LH, Rimsza LM. Simultaneous Drug Targeting of the Promoter MYC G-Quadruplex and BCL2 i-Motif in Diffuse Large B-Cell Lymphoma Delays Tumor Growth. J Med Chem. 2017 08 10; 60(15):6587-6597.
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Fahmi T, Branch D, Nima ZA, Jang DS, Savenka AV, Biris AS, Basnakian AG. Mechanism of graphene-induced cytotoxicity: Role of endonucleases. J Appl Toxicol. 2017 Nov; 37(11):1325-1332.
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Ali N, Rashid S, Nafees S, Hasan SK, Shahid A, Majed F, Sultana S. Protective effect of Chlorogenic acid against methotrexate induced oxidative stress, inflammation and apoptosis in rat liver: An experimental approach. Chem Biol Interact. 2017 Jun 25; 272:80-91.
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Hadden C, Fahmi T, Cooper A, Savenka AV, Lupashin VV, Roberts DJ, Maroteaux L, Hauguel-de Mouzon S, Kilic F. Serotonin transporter protects the placental cells against apoptosis in caspase 3-independent pathway. J Cell Physiol. 2017 Dec; 232(12):3520-3529.
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Zhang Y, Jiao G, Song C, Gu S, Brown RE, Zhang J, Zhang P, Gagnon J, Locke S, Stefanova R, Pelletier C, Zhang Y, Lu H. An Extract from Shrimp Processing By-Products Protects SH-SY5Y Cells from Neurotoxicity Induced by Aß25-35. Mar Drugs. 2017 Mar 22; 15(3).
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Davis HM, Pacheco-Costa R, Atkinson EG, Brun LR, Gortazar AR, Harris J, Hiasa M, Bolarinwa SA, Yoneda T, Ivan M, Bruzzaniti A, Bellido T, Plotkin LI. Disruption of the Cx43/miR21 pathway leads to osteocyte apoptosis and increased osteoclastogenesis with aging. Aging Cell. 2017 06; 16(3):551-563.
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Fry CS, Porter C, Sidossis LS, Nieten C, Reidy PT, Hundeshagen G, Mlcak R, Rasmussen BB, Lee JO, Suman OE, Herndon DN, Finnerty CC. Satellite cell activation and apoptosis in skeletal muscle from severely burned children. J Physiol. 2016 09 15; 594(18):5223-36.
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Park YH, Broyles HV, He S, McGrady NR, Li L, Yorio T. Involvement of AMPA Receptor and Its Flip and Flop Isoforms in Retinal Ganglion Cell Death Following Oxygen/Glucose Deprivation. Invest Ophthalmol Vis Sci. 2016 Feb; 57(2):508-26.
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Hassen S, Ali AA, Kilaparty SP, Al-Anbaky QA, Majeed W, Boman BM, Fields JZ, Ali N. Interdependence of DNA mismatch repair proteins MLH1 and MSH2 in apoptosis in human colorectal carcinoma cell lines. Mol Cell Biochem. 2016 Jan; 412(1-2):297-305.
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Singh P, Sharma R, McElhanon K, Allen CD, Megyesi JK, Beneš H, Singh SP. Sulforaphane protects the heart from doxorubicin-induced toxicity. Free Radic Biol Med. 2015 Sep; 86:90-101.
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Mohamed RH, Karam RA, Hagrass HA, Amer MG, Abd El-Haleem MR. Anti-apoptotic effect of spermatogonial stem cells on doxorubicin-induced testicular toxicity in rats. Gene. 2015 Apr 25; 561(1):107-14.
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Zawada WM, Mrak RE, Biedermann J, Palmer QD, Gentleman SM, Aboud O, Griffin WS. Loss of angiotensin II receptor expression in dopamine neurons in Parkinson's disease correlates with pathological progression and is accompanied by increases in Nox4- and 8-OH guanosine-related nucleic acid oxidation and caspase-3 activation. Acta Neuropathol Commun. 2015 Feb 03; 3:9.
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Fowler TW, Kamalakar A, Akel NS, Kurten RC, Suva LJ, Gaddy D. Activin A inhibits RANKL-mediated osteoclast formation, movement and function in murine bone marrow macrophage cultures. J Cell Sci. 2015 Feb 15; 128(4):683-94.
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Philchenkov AA, Zavelevich MP, Tryndyak VP, Kuiava LM, Blokhin DY, Miura K, Silvestri R, Pogribny IP. Antiproliferative and proapoptotic effects of a pyrrole containing arylthioindole in human Jurkat leukemia cell line and multidrug-resistant Jurkat/A4 cells. . 2015; 16(12):1820-9.
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Thummuri D, Jeengar MK, Shrivastava S, Areti A, Yerra VG, Yamjala S, Komirishetty P, Naidu VG, Kumar A, Sistla R. Boswellia ovalifoliolata abrogates ROS mediated NF-?B activation, causes apoptosis and chemosensitization in Triple Negative Breast Cancer cells. Environ Toxicol Pharmacol. 2014 Jul; 38(1):58-70.
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Eichhorn JM, Alford SE, Sakurikar N, Chambers TC. Molecular analysis of functional redundancy among anti-apoptotic Bcl-2 proteins and its role in cancer cell survival. Exp Cell Res. 2014 Apr 01; 322(2):415-24.
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Carpentieri A, Marchionatti A, Areco V, Perez A, Centeno V, Tolosa de Talamoni N. Antioxidant and antiapoptotic properties of melatonin restore intestinal calcium absorption altered by menadione. Mol Cell Biochem. 2014 Feb; 387(1-2):197-205.
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Ali N, Rashid S, Nafees S, Hasan SK, Sultana S. Beneficial effects of Chrysin against Methotrexate-induced hepatotoxicity via attenuation of oxidative stress and apoptosis. Mol Cell Biochem. 2014 Jan; 385(1-2):215-23.
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Eichhorn JM, Sakurikar N, Alford SE, Chu R, Chambers TC. Critical role of anti-apoptotic Bcl-2 protein phosphorylation in mitotic death. Cell Death Dis. 2013 Oct 03; 4:e834.
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Hodeify R, Megyesi J, Tarcsafalvi A, Mustafa HI, Hti Lar Seng NS, Price PM. Gender differences control the susceptibility to ER stress-induced acute kidney injury. Am J Physiol Renal Physiol. 2013 Apr 01; 304(7):F875-82.
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Bagchi AK, Sharma A, Dhingra S, Lehenbauer Ludke AR, Al-Shudiefat AA, Singal PK. Interleukin-10 activates Toll-like receptor 4 and requires MyD88 for cardiomyocyte survival. Cytokine. 2013 Jan; 61(1):304-14.
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Wang X, Lu J, Khaidakov M, Mitra S, Ding Z, Goyal T, Mehta JL. Delineation of the effects of angiotensin type 1 and 2 receptors on HL-1 cardiomyocyte apoptosis. Apoptosis. 2012 Aug; 17(8):908-15.
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Ni HM, Boggess N, McGill MR, Lebofsky M, Borude P, Apte U, Jaeschke H, Ding WX. Liver-specific loss of Atg5 causes persistent activation of Nrf2 and protects against acetaminophen-induced liver injury. Toxicol Sci. 2012 Jun; 127(2):438-50.
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McGill MR, Sharpe MR, Williams CD, Taha M, Curry SC, Jaeschke H. The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation. J Clin Invest. 2012 Apr; 122(4):1574-83.
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