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Hypoxanthine Phosphoribosyltransferase

"Hypoxanthine Phosphoribosyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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An enzyme that catalyzes the conversion of 5-phosphoribosyl-1-pyrophosphate and hypoxanthine, guanine, or 6-mercaptopurine to the corresponding 5'-mononucleotides and pyrophosphate. The enzyme is important in purine biosynthesis as well as central nervous system functions. Complete lack of enzyme activity is associated with the LESCH-NYHAN SYNDROME, while partial deficiency results in overproduction of uric acid. EC 2.4.2.8.


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This graph shows the total number of publications written about "Hypoxanthine Phosphoribosyltransferase" by people in UAMS Profiles by year, and whether "Hypoxanthine Phosphoribosyltransferase" was a major or minor topic of these publications.
Bar chart showing 14 publications over 10 distinct years, with a maximum of 3 publications in 1997
To see the data from this visualization as text, click here.